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Fulltext - SBU

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Predictor<br />

variables<br />

Validating<br />

criteria<br />

Statistical<br />

methods<br />

Results*<br />

Sensitivity and<br />

specificity<br />

Study<br />

quality and<br />

relevance<br />

Comments<br />

2-step prediction<br />

1. Age 5: Cut-off<br />

for high risk ≥dmft<br />

2. 2 yrs after eruption<br />

of permanent<br />

1st molars: cutt of<br />

for high risk DFT occl<br />

≥1<br />

DMFT ≥3<br />

DMFS ≥4<br />

Proportion<br />

high risk:<br />

Not stated<br />

Se, Sp<br />

For ≥3 DMFT<br />

Se: 78%; Sp: 88%;<br />

PPV: 0.51; NPV:<br />

0.96; accuracy: 0.87<br />

For ≥4 DMFT<br />

Se: 85%; Sp: 85%;<br />

PPV: 0.37; NPV:<br />

0.98; accuracy: 0.85<br />

Low<br />

Heterogeneous<br />

sample.<br />

Incomplete<br />

data<br />

reporting<br />

Estimated no of new<br />

fillings after 1 yr =<br />

≥2 or caries experience<br />

= >1 DFS or<br />

>0 DFS approximal<br />

or salivary flow ≤0.7<br />

ml/min and buffer<br />

capacity =1 or<br />

combined MS and LB<br />

in saliva or combined<br />

DFS and MS, LB in<br />

saliva<br />

≥1 new DFS<br />

≥2 new DFS<br />

Proportion<br />

high risk: 1/3<br />

Se, Sp,<br />

PPV,<br />

NPV*<br />

For ≥1 new DFS<br />

Se: 54%; Sp: 70%;<br />

PPV: 0.71; NPV:<br />

0.52<br />

For ≥2 new DFS<br />

Se: 58%; Sp: 67%;<br />

PPV: 0.57; NPV:<br />

0.68*<br />

Low<br />

Bias from<br />

treatment<br />

likely. Effect<br />

of different<br />

predictors<br />

cannot be<br />

evaluated<br />

The table continues on the next page<br />

KAPITEL 5 • Riskbedömning<br />

257

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