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Table 6.3 continued Author Year, reference Country Study design Blinding Reproducibility test Patient population No Sex Age Baseline prevalence Type of lesions studied Diagnostic criteria Forsman 1974 [10] Sweden RCT school classes Double blind No reliability test N: 135 in each group Female/Male I1: 44/83 (after drop-out) I2: 77/49 (after drop-out) Age: 11–12 years at baseline Mean DMFS: 4–5 Approximal surfaces Own criteria Gisselsson et al 1994 [14] Sweden CCT Blinded Reliability test N: 233 (I: 59, C1: 58, C2: 116) Sex not stated Age: 4 years I: 2.59 C1: 4.53 C2: 4.20 Approximal surfaces, primary molars Gröndahl 1984, Peyron 1992 Heller et al 1995 [11] USA Retrospective follow-up No No reliability test Children in 8 schools All children with ≥1 erupted, not restored or sealed 1st permanent molar were included. All children who completed 5-year followup after fissure sealant N: 113 (I: 96, C: 17) Sex not stated. Age: 7 Mean DFS: 3.1 Occlusal surfaces permanent 1st molars Visual-tactile diagnosis; own criteria 340 Karies – diagnostik, riskbedömning och icke-invasiv behandling
Drop-out Intervention (I) Control (C) Observation time Endpoints Results Study quality and relevance Comments 17 (6%) I1: 0.2% NaF 10 ml rinsing 2 min 1 x/week I2: 0.025% NaF 10 ml rinsing 2 min 1 x/week 2 years Progression or no progression of enamel caries on BW No progression in enamel I1: 67 surfaces I2: 66 surfaces (NS). Significant effect in girls Low Aim of study was not to assess progression. No statistics on progression. Small sample 18 (8%) I: 1% CHX gel applied by flossing 4 x/year C1: Placebo gel applied by flossing 4 x/year C2: No gel treatment All groups F- tablet 0.25 mg 1 x 1 3 years Progression of approximal caries on BW after 2 years I (n=9): 11/28 lesions no progression C1 (n=18): 13/66 lesions no progression p
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Karies - diagnostik, riskbedömning
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Karies - diagnostik, riskbedömning
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Primärt urval av studier 63 Bedöm
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Resultat 176 FOTI 176 DiFOTI 176 DI
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Metodik 356 Litteratursökning 356
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SBU:s sammanfattning och slutsatser
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Bakgrund Karies är en kronisk sjuk
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Gradering av slutsatsernas evidenss
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Visuell-taktil diagnostik Studier s
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Hur kan kariesskador predikteras me
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Barn (1-3 år) som borstar tändern
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Kostnadseffektivitet för diagnosti
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undersöks. Frekvensen röntgenunde
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sönderfall av tanden, då patiente
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av tandhälsan och har inga symtom.
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ning. Riskbedömning görs rutinmä
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Betydelsen av effektiv tidig behand
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Validitet och reliabilitet Validite
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negativa prediktionsvärdet (NPV) b
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ytterligare i Faktaruta 1.6. Exempe
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Samhällsnivå Sociodemografi och v
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Faktaruta 1.1 Olika aspekter på va
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Faktaruta 1.3 Fyrfältstabell med k
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Faktaruta 1.4 Diagram som illustrer
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Faktaruta 1.6 Beräkning av likelih
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Faktaruta 1.7 Nomogram som visar hu
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Referenser 1. Fiske J, Davis DM, Fr
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2. Metodik för sökning och utvär
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Primärt urval av studier För att
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laget för slutsatserna. En metod s
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• Förklarat/analyserat bortfall
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Otillräckligt vetenskapligt underl
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3. Praxisundersökning avseende bit
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svenska och norska tonåringar unde
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Totalt antal undersökta Stockholm
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Østfold Totalt antal undersökta %
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4. Diagnostik 4.1 Visuell-taktil di
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Bakgrund Den primära metoden för
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undersökare och bedömdes ha ett m
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diagnostik av emaljkaries på tuggy
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Aktiv (pågående) och inaktiv (kro
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Tabell 4.1.1 Inklusionskriterier f
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Dropout/ missing data Method or tec
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Table 4.1.7 continued Author, year,
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Referenser 1. Rocha RO, Ardenghi TM
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tion compared with conventional rad
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63. Banerjee A, Watson TF, Kidd EA.
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93. Rosén B, Birkhed D, Nilsson K,
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4.2 Röntgendiagnostik Slutsatser G
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antingen med kabel eller via trådl
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Risker med röntgenstrålning Rönt
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När observatörerna skulle bestäm
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Faktaruta 4.2.2 Nomogrammet som byg
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Metodik för litteraturgenomgång E
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procent och specificiteten mellan 9
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0,1 99 0,2 LR+ LR- 0,5 Visuell insp
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Intern och extern validitet Diagnos
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Kommentarer Vilka tänder eller tan
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för att en tvådimensionell bild a
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Method Number of teeth and surfaces
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52 molars and 11 premolars with occ
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Method Comparison method Outcome me
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Referenser 1. Akdeniz BG, Grondahl
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33. Espelid I, Tveit AB. A comparis
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66. Caliskan Yanikoglu F, Östurk F
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in proximal surfaces versus direct
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131. Wenzel A, Hintze H. The choice
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4.3 Tilläggsmetoder för kariesdia
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kariesskada [81,82]. En diagnostisk
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(a) (b) (c) (d) (e) Figur 4.3.1 Eff
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scerar starkt, medan demineralisera
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förhållandet var tvärtom för pr
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Tabell 4.3.1 Inklusionskriterier f
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Dropout/ missing data Comparison me
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Number of individuals Number of tee
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Number of individuals Number of tee
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Referenser 1. Grossman ES, Cleaton-
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30. Hall AF, DeSchepper E, Ando M,
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of occlusal caries in children. Car
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4.4. Etiska aspekter Som det framg
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• Salivens flöde och/eller buffr
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för riskfaktorn ifråga innan sjuk
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medel vid beslutsfattande. I slutä
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55 procent). Karjalainen och medarb
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Kariesskador i primära tänder som
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som hade högst sockerkonsumtion fa
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Övriga inkluderade studier har lå
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områdena Aiken och Portland i Nort
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studier visar att låg- och mellanr
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Faktaruta 5.1 Inklusionskriterier f
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Table 5.1 Caries prediction in pre-
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Table 5.1 continued Author Year, re
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Table 5.2 Caries prediction in pre-
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Table 5.3 Caries prediction in scho
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Table 5.4 Caries prediction in scho
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Table 5.5 Caries prediction in adul
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Table 5.6 Caries prediction in adul
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Page 288 and 289: Table 5.6 continued Author Year, re
Page 290 and 291: Table 5.7 Tillförlitligheten hos t
Page 292 and 293: Table 5.8 Post-eruptive age as risk
Page 296 and 297: Table 5.9 Post-eruptive age as risk
Page 300 and 301: Table 5.10 Excluded studies. Author
Page 302 and 303: Table 5.10 continued Author, year,
Page 308 and 309: 19. Karjalainen S, Söderling E, Se
Page 310 and 311: social factors and diseases. Int De
Page 312 and 313: isk assessment program in an elderl
Page 314 and 315: 121. Demers M, Brodeur JM, Simard P
Page 316 and 317: study. Community Dent Oral Epidemio
Page 318 and 319: private practice. Community Dent Or
Page 320 and 321: 221. Schröder U, Granath L. Dietar
Page 322 and 323: groups. Oral Surg Oral Med Oral Pat
Page 324 and 325: 287. Ravald N, Birkhed D, Hamp SE.
Page 326 and 327: En nyss frambruten tand är mer mot
Page 328 and 329: Övriga produkter Ozon De syraprodu
Page 330 and 331: En studie, som undersökte effekten
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Page 334 and 335: Table 6.2 Treatment of early corona
Page 336 and 337: Table 6.3 Treatment of early corona
Page 342 and 343: Table 6.4 Treatment of early root s
Page 346 and 347: Table 6.5 Excluded studies. Author,
Page 348 and 349: Referenser 1. Abernathy JR, Graves
Page 350 and 351: composite resin restorations. Acta
Page 353 and 354: 7. Ekonomiska aspekter Slutsatser A
Page 355 and 356: Kostnaden för visuell-taktil under
Page 357 and 358: Faktaruta 7.1 Hur beräknas kostnad
Page 359 and 360: 7.1 7.1 1 800 Kronor Kronor 1 600 1
Page 361 and 362: 8. Tänkbara praxisförändringar T
Page 363: Referenser 1. Ekstrand K. Faglig vi
Page 366 and 367: DFS DFT dft DiFOTI Dikotomisering D
Page 368 and 369: Likelihood-kvot Lingual Makroskopis
Page 370 and 371: Rotcement Sensitivitet Specificitet
Page 372 and 373: Svante Twetman Professor, odontolog
Page 375 and 376: Bilaga 1. Sökstrategier Kapitel 4.
Page 377 and 378: Kapitel 5 fortsättning NOT Cariost
Page 379 and 380: Bilaga 2. Granskningsmallar Diagnos
Page 381 and 382: Studier om riskbedömning Första f
Page 383 and 384: Studier om behandling av tidiga kar
Page 385 and 386: Bilaga 3. Sensitivitet, specificite
Page 387 and 388: 9 8 8,0 8,0 LR+ emalj LR- emalj LR
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Sensitivitet och specificitet 2,0 1
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200 Procent 180 160 140 120 100 80
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180 160 140 120 100 80 60 40 20 0 8
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15. Lussi A. Comparison of differen
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49. Kordic A, Lussi A, Luder HU. Pe
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Ont i ryggen, ont i nacken (2000),
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Rapporter på engelska Obstructive
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