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Dropout/<br />

missing<br />

data<br />

Method<br />

or technique<br />

Comparison<br />

method<br />

Outcome<br />

measure<br />

Results<br />

enamel<br />

caries<br />

Results<br />

dentine<br />

caries<br />

(CI)<br />

Study<br />

quality<br />

and relevance<br />

Comments<br />

Not<br />

reported<br />

VI<br />

Hemisection,<br />

histology<br />

Se, Sp, area<br />

under the<br />

ROC curve<br />

– Se: 72%<br />

Sp: 84%<br />

Medium<br />

Limited to<br />

3rd molars<br />

2 subjects VI Clinical<br />

excavation,<br />

sound/<br />

enamel,<br />

dentine<br />

ROC, Se, – Se: 4%<br />

Sp, A z Sp: 97%<br />

Medium<br />

Not<br />

reported<br />

VI<br />

Hemisection,<br />

histology<br />

Se, Sp,<br />

accuracy<br />

Se: 75%<br />

Sp: 58%<br />

Accuracy:<br />

0.68<br />

Se: 72%<br />

Sp: 84%<br />

Accuracy:<br />

0.72<br />

Medium<br />

Same<br />

material<br />

as Angnes<br />

et al<br />

2005 [13]<br />

VI<br />

52 surfaces<br />

Separation<br />

Se, Sp,<br />

PPV, NPV<br />

– Se: 34%<br />

(20–62)<br />

Sp: 98%<br />

(96–99)<br />

PPV: 0.56<br />

NPV: 0.96<br />

Medium<br />

Se varied<br />

between<br />

12 and 50%<br />

NPV = Negative predictive value; PPV = Positive predictive value; Se = Sensitivity;<br />

Sp = Specificity; VI = Visual inspection; VIP = Visual inspection and probing<br />

KAPITEL 4 • Diagnostik<br />

101

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