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Fulltext - SBU

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Drop-out<br />

Intervention<br />

(I)<br />

Control (C)<br />

Observation<br />

time<br />

Endpoints<br />

Results<br />

Study<br />

quality and<br />

relevance<br />

Comments<br />

– I1: Ozone +<br />

reductant<br />

I2: Reductant<br />

only<br />

I3: Ozone +<br />

reductant +<br />

fissure sealant<br />

I4: Reductant +<br />

fissure sealant<br />

6–12<br />

months<br />

DIAGNOdent<br />

ECM<br />

Reversal<br />

of caries<br />

Progression<br />

of<br />

caries<br />

1 study showed<br />

positive significant<br />

effects<br />

on clinical<br />

severity scores,<br />

diagnodent<br />

and ECM<br />

with ozone +<br />

reductant vs<br />

no ozone. 2<br />

studies showed<br />

no difference<br />

between<br />

groups<br />

Low<br />

The results<br />

are based on<br />

unpublished<br />

studies<br />

Only<br />

those who<br />

completed<br />

the study<br />

included<br />

I: Application<br />

of 2% NaF solution<br />

1 x/week<br />

for 3 weeks,<br />

repeated after<br />

3 months +<br />

application of<br />

NaF solution<br />

every 6 months<br />

C: Application<br />

of NaF solution<br />

every 6 months<br />

2 years,<br />

8 months<br />

New<br />

DFS on<br />

occlusal<br />

surfaces of<br />

permanent<br />

1st molars<br />

% not restored<br />

surfaces:<br />

I: 67%<br />

C: 64% (NS)<br />

Low<br />

The table continues on the next page<br />

KAPITEL 6 • Behandling av tidiga kariesskador<br />

339

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