autologous blood and marrow transplantation - Blog Science ...

0.2 -I
0.0
0
Reece et al.
143
ii i tm II i +(-H H H-M-+ 50%
I
6
Years
95% CI (39 - 60%)
10 12
Figure 1. Progression-free survival after autoSCT in 100 Hodgkin's disease patients.
overall NRM is 19% (95% CI 12-30%) (Fig. 3). The specific causes of NRM are
listed in Table 3. Eight early deaths (100 days) in nine patients.
One patient succumbed to bacterial pneumonia 8 months after autoSCT, and another
died in an automobile accident 52 months after autoSCT. Four died of progressive
pulmonary fibrosis 4.5,6,24, and 24 months after autoSCT. Secondary malignancies
occurred in five patients, at a median of 120 months (range 84—177) after diagnosis
and 49 months (range 34—70) after autoSCT; the cumulative incidence of secondary
malignancies was 9%. 5
Tumor types included glioblastoma multiforme in one patient
1.0
0.8
1 0.4-1
0.2
0.0 4
0
4t-Kfi—I—H I III'—I I t I'
1
6
Years
I HH H—H M II ' I I 38%
95% CI (28-51%)
Figure 2. Relapse rate after autoSCT in 100 Hodgkin's disease patients.
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