28.02.2013 Views

autologous blood and marrow transplantation - Blog Science ...

autologous blood and marrow transplantation - Blog Science ...

autologous blood and marrow transplantation - Blog Science ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

oba<br />

Q.<br />

1.0<br />

0.9<br />

Dicke et al.<br />

Stage IV Breast Cancer<br />

CAT C Survival<br />

'"I..<br />

n = 34<br />

Alive = 2<br />

0.8 1 . Med Survival = 13 months<br />

0.7<br />

0.6<br />

0.5<br />

0.4<br />

—<br />

0.3 —<br />

0.2<br />

—<br />

0.1 —<br />

"I<br />

L,<br />

L,<br />

n<br />

_ _<br />

] u<br />

! 1<br />

1 .<br />

, 1<br />

0.0 1 1 1<br />

1 1 1 1 1 1 1<br />

20<br />

Months From HD To FU<br />

40<br />

337<br />

Median<br />

Figure 5. Survival of category C metastatic breast cancer. On the horizontal axis, the tim<br />

from onset of high dose (HD) to last follow-up has been plotted. N, number of patients un<br />

study; Med Survival, median survival.<br />

breast cancer: Who should be offered alternative initial therapies? Breast Cancer Res Treat<br />

13:33-38, 1989.<br />

3. Spitzer G, Deisseroth A, Ventura G, Jagannath S, Fogel B, Taylor K, Huan S, Dunphy F,<br />

Dicke K, Souza L: Use of recombinant human hematopoietic growth factors <strong>and</strong> autolo­<br />

gous bone <strong>marrow</strong> <strong>transplantation</strong> to attenuate the neutropenic trough of high-dose ther­<br />

apy. Int J Cell Cloning 1:249-261, 1990.<br />

4. Dunphy FR, Spitzer G, Buzdar AU, Hortobagyi GN, Horwitz LJ, Yau JC, Spinolo JA,<br />

Jagannath S, Holmes F, Wallerstein RO, Bohannan PA, Dicke KA: Treatment of estro­<br />

gen receptor-negative or hormonally refractory breast cancer with t<strong>and</strong>em high dose<br />

chemotherapy intensification <strong>and</strong> bone <strong>marrow</strong> support. J Clin Oncol 8:1207-1216,1990.<br />

5. Hood DL, Dicke KA, Donneil PJ, Sowell LK, Fulbright LK: Cytokeratin labeling with<br />

flow cytometry analysis to detect minimal disease in the <strong>marrow</strong> <strong>and</strong> <strong>blood</strong> of breast <strong>and</strong><br />

lung cancer patients (Abstract). T<strong>and</strong>em BMT Meeting, Keystone, CO, February<br />

28-March 3, 1999.<br />

6. Philip T, Armitage JO, Spitzer G, Chauvin F, Jagannath S, Cahn JY, Colombat P, Goldstone<br />

AH, Gorin NC, Flesh M, LaPorte JP, Maraninchi D, Pico J, Bosly A, Anderson C, Schots<br />

R, Biron P, Cabanillas F, Dicke KA: High dose therapy <strong>and</strong> <strong>autologous</strong> bone <strong>marrow</strong> trans­<br />

plantation after failure of conventional chemotherapy in adults with intermediate grade or<br />

high grade non-Hodgkin's lymphoma. N Engl J Med 316:1493-1498, 1987.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!