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World:<br />

Health, Education, Science and Welfare:<br />

Persistent pollutants slow <strong>the</strong> time to pregnancy in couples.<br />

Buck Louis, GM, R Sundaram, EF Schisterman, AM Sweeney, CD<br />

Lynch, RE Gore-Langton, J Maisog, S Kim, Z Chen and DB Barr.<br />

Context<br />

Human and animal studies suggest a link between exposure<br />

to persistent environmental chemicals and decreased fertility.<br />

These chemicals include a number <strong>of</strong> syn<strong>the</strong>tic compounds used<br />

in industrial and agricultural settings as insulators, lubricants,<br />

pesticides and fungicides.<br />

Many <strong>of</strong> <strong>the</strong> worst are called persistent organic pollutants<br />

(POPs). Most POPs were banned from use decades ago under<br />

<strong>the</strong> worldwide Stockholm Convention. These "dirty dozen"<br />

chemicals remain in <strong>the</strong> environment because <strong>the</strong>y degrade<br />

slowly, accumulate in fat tissues, and can biomagnify – or<br />

concentrate – in <strong>the</strong> food chain.<br />

O<strong>the</strong>r types <strong>of</strong> persistent chemicals are still used in<br />

products and industrial settings. Flame retardants – known as<br />

PBDEs – slow burning <strong>of</strong> clo<strong>the</strong>s, furniture, electronics and<br />

o<strong>the</strong>r household items. Perfluorinated compounds – commonly<br />

called PFCs – repel stains and water. Some chemicals in both<br />

groups are being voluntarily phased out because <strong>of</strong> health<br />

concerns.<br />

People, however, continue to be exposed to <strong>the</strong>se chemicals<br />

in daily life. In fact, <strong>the</strong>se persistent chemicals are routinely<br />

detected in human blood, urine and even within <strong>the</strong> reproductive<br />

tract (Jirsová et al. 2010; DeFelip et al. 2004).<br />

Couples exposed to high levels <strong>of</strong> certain persistent organic<br />

pollutants took about 20 percent longer to get pregnant than couples with<br />

lower exposures. This study, which followed couples from Michigan and

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