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UC Davis General Catalog, 2006-2008 - General Catalog - UC Davis

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268 Evolution and Ecology<br />

medicine, including outbreak investigation, infectious<br />

disease epidemiology, properties of tests, and<br />

an introduction to epidemiologic study design and<br />

surveillance. (Same course as Preventive Veterinary<br />

Medicine 405.)—I. (I.)<br />

205B. Integration of Epidemiologic<br />

Concepts (2)<br />

Discussion—2 hours. Prerequisite: Preventive Veterinary<br />

Medicine 405/course 205A can be taken concurrently.<br />

In-depth analysis and integration of basic<br />

epidemiologic concepts and approaches to epidemiologic<br />

research presented in Preventive Veterinary<br />

Medicine 405/course 205A, with more mathematical<br />

and theoretical basis and examples from veterinary<br />

and human medicine, including outbreak<br />

investigation, infectious disease epidemiology, properties<br />

of diagnostic tests, study design, and surveillance.—I.<br />

(I.)<br />

206. Epidemiologic Study Design (3)<br />

Lecture—1.5 hours; discussion—0.9 hours; laboratory—1.8<br />

hours. Prerequisite: Preventive Veterinary<br />

Medicine 405/course 205A, course 205B. Builds<br />

on concepts presented in course 205A. Concepts of<br />

epidemiologic study design—clinical trials, observational<br />

cohort studies, case control studies—introduced<br />

in course 205A are covered in more depth,<br />

using a problem-based format. Discussion of published<br />

epidemiologic studies. (Same course as Preventive<br />

Veterinary Medicine 406A.)—II. (II.)<br />

207. Advanced Concepts in Epidemiologic<br />

Study Design (4)<br />

Lecture/discussion—4 hours. Prerequisite: course<br />

205B and 206. In-depth integration of advanced<br />

concepts in study design, with theory and examples,<br />

including confounding, effect modification under<br />

additive and multiplicative models, internal and<br />

external validity, bias, misclassification, alternate<br />

designs, source populations, statistical power and<br />

sample size, causation, and genetic epidemiology.—III.<br />

Gold, Kass<br />

208. Analysis and Interpretation of<br />

Epidemiologic Data (3)<br />

Lecture—16 sessions; laboratory—21 sessions;<br />

project. Prerequisite: course 204 (may be taken concurrently)<br />

and 207, and either Statistics 144 or Population<br />

Health and Reproduction 202 and entry level<br />

skill in standard statistical software (e.g., SPSS,<br />

BMDP, SAS, Stata, MinTab, S-Plus). Application of<br />

theory and concepts of statistics and epidemiology<br />

to analysis and interpretation of data typically found<br />

in veterinary and human epidemiologic research.—<br />

III. Beckett<br />

210A. Analytic Epidemiology I: Case-<br />

Control Studies (3)<br />

Lecture—2 hours; laboratory/discussion—3 hours.<br />

Prerequisite: Statistics 130B and Preventive Veterinary<br />

Medicine 406 (or the equivalent), or consent of<br />

instructor. Theory and practice of epidemiologic<br />

data analysis. Topics include confounding, stratification,<br />

matching, interaction, and logistic regression.<br />

(Same course as Population Health and Reproduction<br />

210A.)—II. (II.) Kass<br />

210B. Analytic Epidemiology II: Cohort<br />

Studies (3)<br />

Lecture—3 hours. Prerequisite: course 210A. Theory<br />

and practice of epidemiologic data analysis. Topics<br />

include rates, rate standardization, cohort analysis,<br />

Poisson regression, and survival/failure-time methods.<br />

(Same course as Population Health and Reproduction<br />

210B.)—III. (III.) Kass<br />

220. Problems in Epidemiologic Study<br />

Design (4)<br />

Lecture—3 hours; term paper. Prerequisite: Preventive<br />

Veterinary Medicine 405 and 406 or the equivalent;<br />

Population Health and Reproduction 207<br />

concurrently; Statistics 102 and 106 or the equivalent.<br />

Design and development of research protocols<br />

and funding applications for peer review. Application<br />

of research methods data collection and management<br />

and statistical analysis in research<br />

proposals. Methods of evaluating research proposals,<br />

mechanisms of funding, specifying human subjects<br />

considerations.—III. (III.) Gold<br />

222. Epidemiological Modeling (3)<br />

Lecture—2 hours; laboratory—3 hours. Prerequisite:<br />

Preventive Veterinary Medicine 405. Techniques of<br />

model building and simulation of infectious diseases<br />

will be explored. Epidemiologic modeling philosophy,<br />

construction and validation will be emphasized.<br />

Offered in alternate years.—II. Carpenter<br />

223. Spatial Epidemiology (3)<br />

Lecture—2 hours; laboratory—3 hours. Prerequisite:<br />

Preventive Veterinary-Medicine 405 or Environmental<br />

Studies 126 or Veterinary Medicine 409. Geographic<br />

Information Systems (GIS) and spatial<br />

statistics. Students are expected to complete a term<br />

project based on their graduate research. Offered in<br />

alternate years.—II. Carpenter<br />

224. Health and Ecological Risk Analysis<br />

(3)<br />

Lecture—2 hours; laboratory—3 hours. Prerequisite:<br />

Preventive Veterinary Medicine 406 or consent of<br />

instructor; background in statistics, including multivariable<br />

techniques; a course in differential equations.<br />

A methodological approach to risk analysis for<br />

human and animal-related health and ecological<br />

issues. Basic principles of risk analysis, including<br />

perception, communication, assessment and management.<br />

Emphasis on the assessment of risk.—III.<br />

(III.) Carpenter<br />

225. Advanced Topics in Epidemiology<br />

Methods (2)<br />

Discussion—2 hours. Prerequisite: courses 205B,<br />

206, and 207 (or equivalents, with consent of<br />

instructor). An in-depth study of topics in epidemiology<br />

theory and methods, selected from: causal inference,<br />

confounding, study design, or other related<br />

areas, with year to year variation. Readings are<br />

assigned and students are expected to lead discussions<br />

on them. May be repeated for credit when<br />

topic differs. Not offered every year.—II, III. (II, III.)<br />

Hertz-Picciotto<br />

228. Quantitative Methods for<br />

Epidemiology (4)<br />

Lecture—3 hours; lecture/discussion—1 hour. Prerequisite:<br />

Mathematics 16A-B or Mathematics 17A-B<br />

or Mathematics 21A-B or equivalent; basic knowledge<br />

of the principles of linear algebra, such as<br />

those taught in mathematics 22A or the equivalent,<br />

is assumed. The application of calculus and linear<br />

algebra techniques to epidemiological problems.<br />

Topics include applications of derivatives, integration,<br />

exponentials and logarithms, multivariable calculus,<br />

infinite series, and vector and matrix algebra,<br />

with examples and problems taken from epidemiology<br />

and related subjects.—I. (I.) Harvey<br />

240. Principles of Injury Epidemiology (3)<br />

Lecture/discussion—3 hours. Overview of the epidemiology<br />

of human injury, including general principles,<br />

surveillance methods, behavioral factors,<br />

environmental factors, treatment issues and engineering<br />

and legal interventions related to vehicular injuries,<br />

drownings, falls, fires and burns, poisonings,<br />

firearm injuries, and other intentional injuries.—I. (I.)<br />

Romano<br />

250. Introduction to Clinical Research<br />

Design and Epidemiology (1)<br />

Lecture—1 hour. Prerequisite: graduate standing or<br />

medical/nursing personnel. For medical personnel<br />

who are or will be involved in medical research.<br />

Review of basics of clinical study design and analysis<br />

of clinical data. (S/U grading only.)—I. (I.)<br />

McCurdy, Romano<br />

251. Environmental Epidemiology (3)<br />

Lecture—3 hours. Prerequisite: Preventive Veterinary-Medicine<br />

405 (may be taken concurrently);<br />

upper division undergraduates who have completed<br />

Environmental Studies 126; or the equivalent. Examination<br />

of the human health effects and the risk of<br />

disease from community, occupational, and personal<br />

exposure to toxic substances. Offered in alternate<br />

years.—I. Gold<br />

260. Epidemiology of Chronic Diseases and<br />

Aging (3)<br />

Lecture/discussion—3 hours. Overview of the epidemi-ology<br />

of chronic disease in old age. Topics<br />

include biology of aging, epidemiology of cardiovascular<br />

disease, neoplasms, osteoporosis and fractures,<br />

psychosocial factors and health in old age,<br />

dementias, functional status and prevention of disease.—II.<br />

(II.)<br />

270. Research Methods in Occupational<br />

Epidemiology (3)<br />

Laboratory/discussion—3 hours. Prerequisite: Environmental<br />

Studies 126 or Preventive Veterinary-Medicine<br />

405; and Statistics 102 or Epidemiology and<br />

Preventive Medicine 402. Methods used in epidemiologic<br />

research on occupational hazards. Topics<br />

include design and analysis of cohort and case-control<br />

studies, sample size, measuring dose, choosing<br />

a control group, validation of employment and<br />

health data, interpreting negative studies, and analysis<br />

software. Offered in alternate years.—III. Beaumont<br />

272. Cancer Epidemiology (2.0)<br />

Recitation—1 hour; discussion—1 hour. Prerequisite:<br />

must have basic understanding of epidemiologic<br />

and statistical concepts that are covered in courses<br />

205A, 205B, 206 (may be taken concurrently), and<br />

Statistics 102. We will cover the underlying concepts<br />

essential to understanding cancer epidemiology,<br />

such as trends in incidence and survival, epidemiologic<br />

methods used to assess cancer etiology, prevention<br />

and control, and an introduction to the<br />

cancerinitiation and progression multi-stage<br />

model.—II. (II.) Butler, Cress<br />

290. Seminars in Epidemiology (1)<br />

Seminar—1 hour. Students will actively participate<br />

in presentation and discussion of ongoing or published<br />

research projects in epidemiology. (S/U grading<br />

only.)—III. (III.)<br />

291. Seminars in Human Health Services<br />

Research and Clinical Epidemiology (1)<br />

Seminar—1 hour. Critical review, evaluation, and<br />

discussion of research in health services and clinical<br />

epidemiology. Presentation of statistical, epidemiologic,<br />

and econometric methods. Students present<br />

their own research and critique the work of others.<br />

May be repeated for credit. (Same course as <strong>General</strong><br />

Medicine 291.) (S/U grading only.)—I, II, III. (I,<br />

II, III.)<br />

298. Group Study (1-5)<br />

Seminar—1-5 hours. Group study in selected areas<br />

of epidemiology.<br />

299. Research (1-12)<br />

Research in selected areas of epidemiology.<br />

(S/U grading only.)<br />

Evolution and Ecology<br />

(College of Biological Sciences)<br />

Maureen Stanton, Ph.D., Chairperson of the Section<br />

Section Office. 2320 Storer Hall<br />

(530) 752-1272; http://www.eve.ucdavis.edu<br />

Faculty<br />

David J. Begun, Ph.D., Professor<br />

James A. Doyle, Ph.D., Professor<br />

Jonathan A. Eisen, Ph.D., Professor<br />

(Medical Microbiology and Immunology)<br />

Brian P. Gaylord, Ph.D., Assistant Professor<br />

Richard K. Grosberg, Ph.D., Professor,<br />

Academic Senate Distinguished Teaching Award<br />

Artyom V. Kopp, Ph.D., Assistant Professor<br />

Charles H. Langley, Ph.D., Professor<br />

Sergey V. Nuzhdin, Ph.D., Professor<br />

Gail L. Patricelli, Ph.D., Assistant Professor<br />

Bruce H. Rannala, Ph.D., Professor<br />

Marcel Rejmanek, Ph.D., Professor<br />

Michael J. Sanderson, Ph.D., Professor<br />

Eric D. Sanford, Ph.D., Assistant Professor<br />

Thomas W. Schoener, Ph.D., Professor<br />

Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2007-<strong>2008</strong> offering in parentheses<br />

<strong>General</strong> Education (GE) credit: ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Social-Cultural Diversity; Wrt=Writing Experience

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