UC Davis General Catalog, 2006-2008 - General Catalog - UC Davis
UC Davis General Catalog, 2006-2008 - General Catalog - UC Davis
UC Davis General Catalog, 2006-2008 - General Catalog - UC Davis
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Microbiology 373<br />
Ted Powers, Ph.D., Assistant Professor<br />
Irwin H. Segel, Ph.D., Professor<br />
Emeriti Faculty<br />
Paul Baumann, Ph.D., Professor Emeritus<br />
Robert E. Hungate, Ph.D., Professor Emeritus<br />
John L. Ingraham, Ph.D., Professor Emeritus<br />
JaRue S. Manning, Ph.D., Professor Emeritus<br />
Allen G. Marr, Ph.D., Professor Emeritus<br />
David Pratt, Ph.D., Professor Emeritus<br />
Merna R. Villarejo, Ph.D., Professor Emerita<br />
Affiliated Faculty<br />
Karen L. Gerhart, Ph.D., Lecturer<br />
Eric D. Mann, Ph.D., Lecturer<br />
The Major Program<br />
Microbiology is the branch of biology that deals<br />
with bacteria, yeasts and other fungi, algae, protozoa,<br />
and viruses. These microorganisms are ubiquitous<br />
in nature and play a crucial role in areas such<br />
as agriculture, biotechnology, ecology, medicine,<br />
and veterinary science. The field of microbiology<br />
contributes to areas of fundamental inquiry such as<br />
biochemistry, cell biology, evolution, genetics,<br />
molecular biology, pathogenesis, and physiology.<br />
The ease and power of simultaneous genetic and<br />
biochemical analysis of microbes led to the emergence<br />
of the new disciplines of molecular biology<br />
and molecular genetics, and spawned the new<br />
industry of biotechnology.<br />
The Program. Both undergraduate major programs<br />
provide a balance of studies in microbiology,<br />
with appropriate courses in mathematics and physical<br />
sciences. The A.B. degree program emphasizes<br />
the biology of bacteria, while the B.S. degree program<br />
includes more biochemistry and related course<br />
work. Either program, with judicious course selection,<br />
is appropriate for students contemplating a<br />
career in medicine or various allied health professions<br />
including medical technology, or teaching. The<br />
B.S. program is especially well suited for students<br />
who want a professional career in microbiology, or<br />
who wish to pursue graduate education in a biological<br />
science discipline. The choice of a major program<br />
and its suitability for particular career options<br />
should be discussed with a major adviser.<br />
Career Alternatives. A bachelor’s degree in<br />
microbiology is excellent preparation for a career in<br />
biotechnology, pharmacology, agriculture, and the<br />
food industry. It also provides a strong background<br />
for students wishing to continue on to professional<br />
studies in medicine and the other health sciences.<br />
A.B. Major Requirements:<br />
UNITS<br />
Preparatory Subject Matter.............. 43-57<br />
Biological Sciences 1A-1B-1C................ 15<br />
Chemistry 2A-2B.................................. 10<br />
Chemistry 8A-8B or 118A-118B-<br />
118C .............................................. 6-12<br />
Mathematics 16A-16B, 17A-17B or<br />
21A-21B............................................ 6-8<br />
Physics 1A-1B or 7A-7B-7C ................ 6-12<br />
Depth Subject Matter ....................... 37-45<br />
Biological Sciences 101, 102, 103........ 10<br />
Microbiology 102, 102L, 105, 105L,<br />
140.................................................... 16<br />
Microbiology 162 or Pathology,<br />
Microbiology, and Immunology 128...... 3-4<br />
Three additional courses from Food Science<br />
and Technology 104; Medical Microbiology<br />
115, 116, 130; Microbiology 100, 120,<br />
150, 155L, 160, 170; Molecular and<br />
Cellular Biology 120L; Pathology,<br />
Microbiology, and Immunology 127; Plant<br />
Pathology 120, 130, 148, 150; Soil Science<br />
111; Statistics 100, 102.................... 8-15<br />
Total Units for the Major ................ 80-102<br />
B.S. Major Requirements:<br />
UNITS<br />
Preparatory Subject Matter.............. 60-70<br />
Biological Sciences 1A-1B-1C................ 15<br />
Chemistry 2A-2B-2C............................. 15<br />
Chemistry 8A-8B or 118A-118B-<br />
118C ...............................................6-12<br />
Mathematics 16A-16B-16C or 17A-17B-<br />
17C .................................................9-12<br />
Physics 7A-7B-7C................................. 12<br />
Statistics 13, 32, 100 or 102................3-4<br />
Depth Subject Matter .......................47-51<br />
Biological Sciences 101, 102, 103,<br />
104 ................................................... 13<br />
Molecular and Cellular Biology 120L ....... 6<br />
Microbiology 102, 102L, 105, 105L .... 13<br />
Two courses from Microbiology 140, 150,<br />
or 170 ................................................. 6<br />
Microbiology 162 or Pathology,<br />
Microbiology, and Immunology 128 ......3-4<br />
Two courses from Food Science and<br />
Technology 104; Microbiology 120, 140,<br />
150, 155L, 160, 170, Pathology,<br />
Microbiology, and Immunology 127; Soil<br />
Science 111........................................6-9<br />
Total Units for the Major ..............107-121<br />
Master Adviser. M.L. Wheelis in 2033D Sciences<br />
Lab Building<br />
Honors and Honors Program. M.L. Wheelis<br />
Teaching Credential Subject Representative.<br />
M.L. Wheelis; see the Teaching Credential/M.A.<br />
Program on page 102.<br />
Graduate Study. The Graduate Group in Microbiology<br />
offers programs of study and research leading<br />
to the M.S. and Ph.D. degrees.<br />
Strong preference is given to doctoral applicants.<br />
The group offers study in general microbiology,<br />
microbial physiology, microbial genetics, molecular<br />
mechanisms of microbial regulation, molecular<br />
mechanisms of microbial pathogenesis, immunology,<br />
virology, and recombinant DNA technology. For<br />
information on the graduate study and undergraduate<br />
preparation for the program contact a graduate<br />
adviser or the Chairperson of the Group.<br />
Related Courses. The offerings of the Section of<br />
Microbiology are augmented by courses and faculty<br />
of Evolution and Ecology; Food Science and Technology;<br />
Land, Air, and Water Resources; Medical<br />
Microbiology; Medicine and Epidemiology; Molecular<br />
and Cellular Biology; Pathology, Microbiology,<br />
and Immunology; Plant Biology; Plant Pathology;<br />
Viticulture and Enology.<br />
Faculty of the Section of Microbiology also teach or<br />
participate in the following courses: Biological Sciences<br />
1A, 10, 101 and 104.<br />
Courses in Microbiology (MIC)<br />
Lower Division Courses<br />
10. Natural History of Infectious Diseases<br />
(3)<br />
Lecture—3 hours. Topics in the natural history of<br />
infectious diseases principally affecting humans.<br />
Introduction to infectious microbial agents, ecology,<br />
epidemiology, and induction of disease. Focus on<br />
diseases of a contemporary nature. For students not<br />
majoring in the biological sciences. GE credit: Sci-<br />
Eng.—II. (II.)<br />
98. Directed Group Study (1-5)<br />
Prerequisite: consent of instructor. Primarily for lower<br />
division students. (P/NP grading only.)<br />
99. Special Study for Undergraduates (1-5)<br />
(P/NP grading only.)<br />
Upper Division Courses<br />
100. Chemical and Biological Weapons (3)<br />
Lecture/discussion—3 hours. Prerequisite: upper<br />
division standing. Ancient and modern history of<br />
chemical and biological weapons; mechanism of<br />
action; tactical and strategic uses; riot-control<br />
agents; international legal constraints; disarmament<br />
and nonproliferation; genomics and the future. GE<br />
credit: SciEng or SocSci.—II. (II.) Wheelis<br />
102. <strong>General</strong> Bacteriology (4)<br />
Lecture—4 hours. Prerequisite: Biological Sciences<br />
1A and Chemistry 8B or Chemistry 118B (may be<br />
taken concurrently). Survey of the biology of bacteria<br />
and viruses, including bacterial structure, metabolism,<br />
physiology, genetics, and evolution; viral<br />
structure and replication; the role of bacteria in global<br />
element cycles; and the role of microbes in infectious<br />
disease.—I, II, III. (I, II, III.)<br />
102L. <strong>General</strong> Bacteriology Laboratory (3)<br />
Lecture/laboratory—7 hours. Prerequisite: course<br />
102 (may be taken concurrently) and consent of<br />
instructor. Introduction to principles and laboratory<br />
methods employed in working with microorganisms.<br />
For students planning to continue the study of microbiology<br />
or to use microorganisms as tools for the<br />
study of genetics and biochemistry.—I, II, III.<br />
105. Bacterial Diversity (3)<br />
Lecture—3 hours. Prerequisite: consent of instructor;<br />
courses 102 and 102L; Biological Sciences 102;<br />
Biological Sciences 103 recommended. Survey of<br />
the major groups of bacteria emphasizing diversity<br />
of energy metabolism, morphology and natural history.<br />
Not open for credit to students who completed<br />
course 105 in 2005 or earlier.—II. (II.) Parales,<br />
Wheelis<br />
105L. Bacterial Diversity Laboratory (3)<br />
Laboratory—9 hours. Prerequisite: consent of instructor;<br />
courses 102 and 102L; course 105 (may be<br />
taken concurrently); Biological Sciences 102; Biological<br />
Sciences 103 recommended. Laboratory—nine<br />
hours (eight hours scheduled lab periods; one hour<br />
during open laboratory). Isolation and characterization<br />
of bacterial strains from various habitats.<br />
Includes methods for determination of evolutionary<br />
relationships among groups. Not open for credit to<br />
students who completed course 105 in 2005 or earlier.—II.<br />
(II.) Nelson, Parales<br />
120. Microbial Ecology (3)<br />
Lecture—3 hours. Prerequisite: course 105, Biological<br />
Sciences 102. Interactions between non-pathogenic<br />
microorganisms and their environment,<br />
emphasizing physiological and metabolic characteristics<br />
of various groups and their adaptation to and<br />
modification of specific habitats.—III. (III.) Wheelis<br />
120L. Microbial Ecology Laboratory (2)<br />
Laboratory—6 hours; one optional overnight weekend<br />
field trip. Prerequisite: course 120 (may be<br />
taken concurrently); consent of instructor. Study of<br />
prokaryotic microorganisms from certain habitats.<br />
One-half of laboratory effort will consist of organized<br />
experiments on ecologically important microbial<br />
activities. For remaining one-half, research<br />
projects will be done on student selected specific<br />
habitats of microorganisms. Limited enrollment. Not<br />
offered every year.<br />
140. Bacterial Physiology (3)<br />
Lecture—3 hours. Prerequisite: Biological Sciences<br />
101, 102, 103 (may be taken concurrently); course<br />
102 recommended (may be taken concurrently).<br />
Fundamentals of bacterial growth and bacterial<br />
responses to environmental stresses. Topics will<br />
include carbon and nitrogen regulation, growth rate<br />
control, post-exponential growth, and motility and<br />
chemotaxis. Not open for credit to students who<br />
have completed course 130A.—I. (I.) Singer, Meeks<br />
150. Bacterial Genetics (3)<br />
Lecture—3 hours. Prerequisite: Biological Sciences<br />
101, 102, Biological Sciences 103 or course 140;<br />
course 102 recommended (may be taken concurrently).<br />
Molecular genetics of enterobacteria and<br />
their viruses. Isolation of mutants; genetic exchange<br />
and mapping; complementation; suppression; transposons;<br />
gene expression and regulation; and<br />
genomics. Examples illustrate applications to molecular<br />
cloning of recombinant DNA, and to the study<br />
of bacterial pathogenesis.—II. Roth, Stewart<br />
155L. Bacterial Physiology Lab (4)<br />
Lecture/discussion—1 hour; laboratory—8 hours.<br />
Prerequisite: course 140 or 150, 102L, consent of<br />
instructor. Physiology and genetics of bacteria. Isolation<br />
and characterization of mutant strains. Mapping<br />
Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2007-<strong>2008</strong> offering in parentheses<br />
<strong>General</strong> Education (GE) credit: ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Social-Cultural Diversity; Wrt=Writing Experience