PDF file: EURASNET Annual Report 2008

241 Evaluate available careerdevelopment training courseswithin the EURASNET networkfor appropriateness for our preandpostdocs (month 36)254 Prepare circulation list ofclinicians and scientists involvedin therapeutic approaches tosplicing diseases. The first yearreport suggested greaterinteraction with medicalscientists and clinicians to raiseawareness of alternativesplicing. Some members ofEURASNET interact withclinicians and medical scientistsand consult or act as experts togroups involved in developmentof therapies for splicing-relateddiseases. We will, via theseEURASNET contacts, establisha list of contacts for suchscientists. Information onupcoming meetings andworkshops organised byEURASNET will circulated tothis group. (month 36).255 Modify proforma for capturinginformation. The proforma usedto capture information onvarious activities in terms ofbroader outreach to the RNAcommunity will be modified onthe basis of feedback frommembers (month 36).146 Reorganization and re-siting ofwebsite (month 36)183 Replace low information contentArabidopsis AS events withother selected AS events andcharacterise novel events (month36)147 Design of new website with newfunctionality and transfer ofinformation (month 36)226 Proof of principle foridentification of proteininteraction surfaces by efficientmutagenesis (month 36)227 Set up a high-throughput cloningsystem for minigenes that allowsrapid analysis of alternativeexons (month 36)228 Development of FLIM-FRETfor mapping protein-proteininteractions at specificsubcellular (and subnuclear)locations in vivo (month 36)148 Database of substances thatchange alternative splicing(month 36)18 36 36 Kjems21 36 36 Brown21 36 36 Brown1 36 30 Brown8 36 34 Smith1 36 36 Brown15 36 36 Séraphin15 36 36 Séraphin15 36 36 Séraphin1 36 36 Brown95