PDF file: EURASNET Annual Report 2008

258 Prepare Annual Report for 2008period (month 38).250 Develop a stable cell line forevaluating the effect of chemicalinhibitors on pre-mRNA splicingin vivo (month 40).235 2009 Annual Meeting, Assisi,April, 2009 To be organized byparticipant G. Biamonti (month40)242 Pursue the possibility ofselecting one program for a 1-2day career developmentworkshop in which participantsget hands-on training in thechosen topic (eg writing the cv,giving a talk or an interview,making and presenting a poster)(month 41)93 Analyse the post-translationalmodifications of spliceosomalproteins at defined functionalstages of the spliceosome, withparticular emphasis onphosphorylation (month 30).149 Liaise with targeted audiencesand prepare appropriate content(month 42)150 Tools and resources repositoryupdated (month 42).151 Implementation of an improvedweb entry form for protocolsthat takes into account feedbackof EURASNET members andparticipants of the practicalcourses.152 The current filemaker basedsystem is slow and cumbersometo use. The pages will bereprogrammed using HTMLwith an easy to use interface(Month 36). As suggested bymany users, there will be astronger emphasis onbackground (why is thisprocedure done) as well as asearchable index.153 Publication of the protocols as apdf booklet on the EURASNETweb site and publishing of aprotocol book (Month 42)154 Fast DB already contains analgorithm that allows analysis ofAffymetrix splicearray datafiles.We will create an interface thatallows direct visualization ofsplicearray data in FAST DB(month 42).155 Integration of an algorithm thatcomputes the likelihood ofsequences to be single stranded(PU) values into FAST DB(month 42).22 38 39 Lührmann20 40 on target Lamond16 40 40 Beggs18 41 41 Kjems10 30 30 Cáceres1 42 ongoing (42) Brown1 42 ongoing (42) Brown2 42 36 Stamm2 36 36 Stamm2 42 on target Stamm4 42 36 Apweiler4 42 on target Apweiler96