Final Program
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SUNDAY • MAY 15 123<br />
221 Acid and Non-Acid Reflux in Idiopathic Pulmonary Fibrosis/T.<br />
Lee, L. Liu, S. Shapera, T.K. Marras, J.H. Fisher, Toronto, Canada,<br />
p.A2709<br />
222 Effects of Emphysema on Physiologic and Prognostic<br />
Characteristics in Idiopathic Pulmonary Fibrosis/T. Kim, S.M.<br />
Lee, N. Kim, J.B. Seo, J.W. Song, Seoul, Korea, Republic of,<br />
p.A2710<br />
223 Prognostic Value of Plasma Leptin in Acute Exacerbation<br />
Idiopathic Pulmonary Fibrosis/M. Cao, J. Swigris, H. Cai,<br />
Nanjing, China, p.A2711<br />
224 Idiopathic Pulmonary Fibrosis in Patients with Possible Usual<br />
Interstitial Pneumonia Pattern on High-Resolution CT/Y.<br />
Kondoh, H. Taniguchi, T. Suda, T. Fujisawa, M. Arita, K. Ichikado,<br />
K. Kishi, T. Kishaba, O. Nishiyama, T. Ogura, S. Homma, Seto,<br />
Japan, p.A2712<br />
225 Reduction in Non-Elective Respiratory-Related Hospitalizations<br />
in Patients Treated with Pirfenidone: Pooled Analyses from<br />
Three Phase 3 Trials of Pirfenidone in Idiopathic Pulmonary<br />
Fibrosis/J. Swigris, B.J. Ley, B.-M. Day, J. Stauffer, W. Chou, K.<br />
Raimundo, H.R. Collard, Denver, CO, p.A2713<br />
A104<br />
POSTER DISCUSSION SESSION<br />
CRITICAL CARE: SEPSIS TRANSLATIONAL<br />
INSIGHTS<br />
2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />
Room 3001 (West Building, Level 3)<br />
Poster Viewing 2:15-3:00<br />
Discussion 3:00-4:15<br />
Chairing: M.M. Wurfel, MD, PhD, Seattle, WA<br />
W. Fang, MD, Kaohsiung, Taiwan<br />
E.P. Schmidt, MD, Aurora, CO<br />
701 Identifying Time-Dependent Mortality Signatures in Cases of<br />
Suspected Infection Using Scalable Predictive Models/M.B.<br />
Mayhew, A.P. Sales, J.D. Greene, J.M. Baker, A. Santucci, G.J.<br />
Escobar, V. Liu, T. Wasson, Livermore, CA, p.A2714<br />
702 Regulation of Creb-Binding Protein<br />
Ubiquitination-Deubiquitination Modulates Histone Acetylation<br />
and Systemic Inflammation/Y. Zhao, S. Dong, J. Wei, R.K. Boswer,<br />
A. Khoo, L. Zhang, A.M. Jacko, J. Zhao, Pittsburgh, PA, p.A2715<br />
703 Circulating Levels of Interleukin-17A Are Associated with<br />
Mortality and Organ Dysfunction in Sepsis/C. Mikacenic, S.<br />
Harju-Baker, V. Dmyterko, M.M. Wurfel, Seattle, WA, p.A2716<br />
704 Heterogeneous Treatment Effect of Recombinant Human<br />
Interleukin-1 Receptor Antagonist for Human Severe Sepsis/N.J.<br />
Meyer, T.G. Dunn, J.P. Reilly, J.A. Palakshappa, R. Feng, J.D.<br />
Christie, J.E. Palardy, S.M. Opal, Philadelphia, PA, p.A2717<br />
705 Reduced PCSK9 Function Is Associated with Improved Outcomes<br />
in Gram-Positive Septic Shock Patients/E. Topchiy, C. Fjell, J.A.<br />
Russell, J.H. Boyd, K.R. Walley, Vancouver, Canada, p.A2718<br />
706 Lipopolysaccharide Is Cleared from the Circulation by<br />
Hepatocytes Via the Low Density Lipoprotein Receptor/E. Topchiy,<br />
J.H. Boyd, J.A. Russell, K. Walley, Vancouver, Canada, p.A2719<br />
707 Inheritance of Loss-of-Function Tryptase Alleles Is Linked to<br />
Reduced Survival from Severe Sepsis/N. Trivedi, R. Ahuja, K.<br />
Walley, M. Babina, S. Guhl, G. Caughey, San Francisco, CA, p.A2720<br />
708 Modulation of Annexin A2 Expression in Human Sepsis/M.<br />
Bender, F. West, J. Lanfranco, H. Chen, D. Almeida, D. Berlin, K.A.<br />
Hajjar, New York, NY, p.A2721<br />
709 High Levels of Methylarginines Are Associated with Increased<br />
Mortality in Patients with Severe Sepsis/K.M. Mortensen, T.S.<br />
Itenov, N. Haase, R. Muller, S.R. Ostrowski, P.I. Johansson, N.V.<br />
Olsen, A. Perner, P. Soe-Jensen, M. Bestle, Hillerod, Denmark,<br />
p.A2722<br />
710 Plasma Asymmetric Dimethylarginine (ADMA) Association<br />
with Risk of Death in Septic Shock - Subgroup Analysis of<br />
Patients from the VANISH Trial/S. Lambden, J. Leiper, A.<br />
Gordon, London, United Kingdom, p.A2723<br />
711 Increased Receptor Interacting Serine/Threonine-Protein<br />
Kinase 3 Plasma Levels Is Associated with Severity of<br />
Sepsis/K.C. Ma, M. Pabon, E.J. Schenck, E. Finkelsztein, A.<br />
Hernandez, D. Berlin, K. Nakahira, A.M.K. Choi, New York, NY,<br />
p.A2724<br />
712 Impaired Immune Response and Lower Serum<br />
Monocyte/Neutrophil Ratio Can Predict Outcomes in Patients<br />
with Severe Sepsis/W.-F. Fang, H.-C. Kao, Y.-T. Fang, K.-T.<br />
Huang, Y.-H. Wang, C.-H. Huang, Y.-T. Chang, H.-L. Huang, C.-C.<br />
Wang, M.-C. Lin, Kaohsiung, Taiwan, p.A2725<br />
713 Early High Density Lipoprotein (HDL) Level Predicts the<br />
Development of Organ Dysfunction and Mortality in Patients<br />
Presenting with Suspected Sepsis/M. Cirstea, K. Walley, J.<br />
Russell, J. Boyd, Vancouver, Canada, p.A2726<br />
714 Randomised Controlled Trial of Granulocyte Macrophage<br />
Colony Stimulating Factor in Critically Ill Patients with<br />
Impaired Neutrophil Function/E.M. Pinder, A.J. Rostron, T.P.<br />
Hellyer, M.-H. Ruchaud-Sparagano, J. Scott, J.G. Macfarlane, S.<br />
Wiscombe, J.D. Widdrington, T. Allen, A.I. Roy, V.C. Linnett, S.V.<br />
Baudouin, S.E. Wright, T. Chadwick, A. Fouweather, S. Bowett, J.<br />
Parker, P.A. Corris, D.F. D. McAuley, A. Conway Morris, A.<br />
Simpson, Newcastle upon Tyne, United Kingdom, p.A2727<br />
715 Hydrocortisone Treatment Decreases Nitric Oxide Levels and<br />
Increases Blood Pressure and Survival Following B. anthracis<br />
Cell Wall Peptidoglycan Challenge in Rats/D.A. Suffredini, X.<br />
Cui, Y. Li, Y. Fitz, P. Eichacker, Bethesda, MD, p.A2728<br />
716 PCSK9 Loss-of-Function Genotype and Outcomes of Sepsis/K.<br />
Roveran Genga, M. Cirstea, C. Lo, K. Walley, J.A. Russell, J.H.<br />
Boyd, Vancouver, Canada, p.A2729<br />
717 Adipokines Early in Critical Illness/A.M. Ahasic, M. Pisani, New<br />
Haven, CT, p.A2730<br />
718 Acute Respiratory Distress Syndrome Does Not Independently<br />
Predict Mortality Among All Critically Ill Patients with<br />
Sepsis/C.L. Auriemma, H. Zhuo, T. Deiss, T. Liu, M. Lippi, K.R.<br />
Famous, E. Seeley, K.N. Kangelaris, A. Gomez, M. Matthay, K. Liu,<br />
C.S. Calfee, San Francisco, CA, p.A2731<br />
SUNDAY AFTERNOON<br />
ATS 2016 • San Francisco