Final Program
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348 WEDNESDAY • MAY 18<br />
216 Simplifying the Cardiopulmonary Exercise Test Enables<br />
Pattern Recognition and Differentiation Between Diseases<br />
Causing Exertional Dyspnea/K.H. Melamed, B. Dolezal, X. Wang,<br />
C.B. Cooper, Los Angeles, CA, p.A6531<br />
217 Absolute Lung Volume and Breathlessness in Men and Women<br />
in the General Population/M. Ekstrom, L. Schioler, R. Gronseth,<br />
A. Johannessen, C. Janson, C. Svanes, B. Leynaert, D. Jarvis, K.<br />
Toren, Lund, Sweden, p.A6532<br />
218 Validation of the Objective Simplified Wells Score and<br />
Comparison with Clinical Judgement/J. Seashore, M. Farokhi,<br />
J.P. Wisnivesky, O. Epelbaum, Queens, NY, p.A6533<br />
219 Patient Reported Dyspnea on Standardized Questionnaires<br />
Does Not Correlate with Measurement Of maxVO2 During<br />
Cardio-Pulmonary Exercise Testing/D. Gaspard, S. Akers, J.<br />
Kass, M. Pratter, Camden, NJ, p.A6534<br />
220 Correlation of Self Reported Breathlessness with Post<br />
Exercise Dyspnea in Obesity/M. Agustin, H. Chang, J. Unterborn,<br />
A. Andoh-Duku, Boston, MA, p.A6535<br />
221 Interstitial Lung Disease Patient Diagnostic Journey<br />
(INTENSITY) Survey/P. Bianchi, D.J. Lederer, S. Danese, J.<br />
Loboda, G. Cosgrove, South San Francisco, CA, p.A7894<br />
D24<br />
POSTER DISCUSSION SESSION<br />
GRAM NEGATIVE PNEUMONIAS: FROM BENCH TO<br />
BEDSIDE<br />
9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />
Room 3014 (West Building, Level 3)<br />
Poster Viewing 9:00-9:45<br />
Discussion 9:45-11:00<br />
Chairing: J.E. Chastre, MD, Paris, France<br />
C.S. Dela Cruz, MD, PhD, New Haven, CT<br />
M.S. Niederman, MD, New York, NY<br />
901 Alterations in Pseudomonas Aeruginosa Pathogenicity in<br />
Response to Cigarette Smoke Exposure/M. Ahn, J.H. Hwang, E.<br />
McEachern, L.E. Crotty Alexander, San Diego, CA, p.A6536<br />
902 The Fermentation Product 2,3-butanediol Alters P. aeruginosa<br />
Virulence and the Lung Microbiome/A. Sharma, M. Nguyen, W.<br />
Wu, R. Gomi, L. Angenent, S. Worgall, New York, NY, p.A6537<br />
903 Chitinase 3-Like 1 (Chil1) Regulates Pseudomonas-Induced<br />
Inflammasome Activation Independent of the Inflammasome<br />
Nlrc4 Highlights Importance of Nlrp3 Mediated Lung<br />
Pathology/C.R. Marion, W. Liu, L. Sharma, R. Singh, J. Wang,<br />
C.G. Lee, J.A. Elias, B. Kazmierczak, C. Dela Cruz, New Haven,<br />
CT, p.A6538<br />
904 The Signaling Pathway Involved in MUC1 Mucin Upregulation<br />
in Macrophages During Pseudomonas Aeruginosa Infection/K.<br />
Kato, A. Hanss, N. Morgan, K.S. Knox, E.P. Lillehoj, K.C. Kim,<br />
Tucson, AZ, p.A6539<br />
905 Thrombocytopenia Impairs Host Defence in a Murine Model of<br />
Pulmonary Infection with Psuedomonas Aeruginosa/R.T.<br />
Amison, A. Rossi, S. Ranucci, S. Arnold, S.C. Pitchford, A.<br />
Bragonzi, C.P. Page, London, United Kingdom, p.A6540<br />
906 Interleukin 7 Immunotherapy Improves Survival in Sepsis<br />
Followed by Secondary Pseudomonas Aeruginosa<br />
Pneumonia/Y. Shindo, A.G. Fuchs, C.G. Davis, J. Unsinger, T.<br />
Eitas, C.-A. Burnham, J.M. Green, G.V. Bochicchio, R.S.<br />
Hotchkiss, St. Louis, MO, p.A6541<br />
907 Severity-of-Illness Scores Predict Failure of Antibiotic Therapy<br />
in Pseudomonas Aeruginosa Pneumonia/R.D. Shah, R.G.<br />
Wunderink, Chicago, IL, p.A6542<br />
908 Molecular Characteristics and Epidemiology of Clinically<br />
Tested Non-Extended-Spectrum b-Lactamase<br />
(ESBL)-Producing Klebsiella Pneumoniae Isolates in China/Z.<br />
Zhang, Y. Zhai, Y. Guo, D. Li, Z. Wang, Y. Chen, J. Wang, Q.<br />
Wang, Z. Gao, Beijing, China, p.A6543<br />
909 Promoter-Associated blaSHV Extended-Spectrum<br />
Beta-Lactamases (ESBLs) Phenotypic Silencing in Klebsiella<br />
Pneumoniae/Y. Zhai, Z. Zhang, Y. Guo, Y. Lv, Z. Wang, L. Liu, L.<br />
Xu, D. Yang, R. Li, Y. Xu, J. Yang, Y. Chen, Q. Wang, Z. Gao,<br />
Beijing, China, p.A6544<br />
910 Interleukin (IL)-1a and IL-1b Contribute to Host Defense<br />
Against Pulmonary Klebsiella Infection Via Different<br />
Mechanisms/S. Cai, P. Baral, L. Jin, S. Jeyaseelan, Baton Rouge,<br />
LA, p.A6545<br />
911 Diet-Induced Obesity Impairs Pulmonary Bacterial Clearance<br />
in Klebsiella Pneumonia/P. Mancuso, J.B. Weinberg, K. Singer,<br />
Ann Arbor, MI, p.A6546<br />
912 Epithelial IL-17R Is Required for Pulmonary Host Defense<br />
Against K. Pneumonaie/K. Chen, G. Trevejo-Nunez, E.E. Way,<br />
W. Elsegeiny, D.M. Ricks, A.V. Garg, S.L. Gaffen, J.K. Kolls,<br />
Pittsburgh, PA, p.A6547<br />
913 Effects of Carbapenemase-Producing K. Pneumoniae ST258<br />
on the Components of the Airway Epithelial Barrier/M.<br />
Wickersham, A.S. Prince, D. Ahn, New York, NY, p.A6548<br />
914 ST191 Belonging to CC92 Became Dominate<br />
Carbapenem-Resistant Acinetobacter Baumannii that Cause<br />
Nosocomial Pneumonia in Intensive Care Units in a Teaching<br />
Hospital in Central China/P. Pan, H. Tan, M. Li, X. Su, C. Hu,<br />
ChangSha, China, p.A6549<br />
915 Outcome and Prognostic Factors of Pneumonia Patients with<br />
Acinetobacter Baumannii Bacteremia/W.-C. Liao, C.-H. Chen,<br />
W.-C. Chen, B.-R. Wu, C.-Y. Chen, W.-C. Cheng, T.-C. Hsia, C.-Y.<br />
Tu, Taichung, Taiwan, p.A6550<br />
916 Multidrug Resistance in Acinetobacter Baumannii Pneumonia<br />
and Sepsis Increases the Risk of Receiving Inappropriate<br />
Empiric Treatment/M. Zilberberg, B.H. Nathanson, K. Sulham, W.<br />
Fan, A.F. Shorr, Goshen, MA, p.A6551<br />
917 Effectiveness of High Dose Sulbactam for the Treatment of<br />
Ventilator Associated Pneumonia Caused by Carbapenem<br />
Resistant Acinetobacter Baumanii/I. Jeong, J.W. Son, M.J. Na,<br />
S.J. Kwon, Daejeon, Korea, Republic of, p.A6552<br />
ATS 2016 • San Francisco