Final Program

MONDAY • MAY 16 137
B5
BASIC • TRANSLATIONAL
BASIC SCIENCE CORE
CME Credits Available: 2.0
HARNESSING BREAKTHROUGHS IN CRISPR GENE
EDITING TECHNOLOGY FOR RESEARCH AND
THERAPY
Assemblies on Respiratory Cell and Molecular Biology; Allergy,
Immunology and Inflammation; Microbiology, Tuberculosis and Pulmonary
Infections; Respiratory Structure and Function; Thoracic Oncology
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Room 2009/2011 (West Building, Level 2)
Target Audience
Basic and translational researchers seeking to understand the most important
advance in biotechnology in the last decade and clinical investigators and
clinicians interested in learning more about this technology that is poised to
move into clinical application in the coming decade.
Objectives
At the conclusion of this session, the participant will be able to:
• learn new findings about the CRISPR system functions and how it can be
adapted to edit human and other animal genomes;
• improve lung research by learning new strategies for selectively turning
genes on and off, creating lung cancer models, performing genome-wide
screens, and imaging the genome;
• contribute to conversations that will shape scientific and ethical approaches
to the use of CRISPR technology to treat human disease.
The development of the CRISPR system for efficient and selective editing of the
human genome represents the most important scientific breakthrough of the
past decade. CRISPR-based systems are already being widely used for
inactivating or repairing individual genes in human cells and animal models and
for genome-wide studies of the functions of coding and non-coding RNAs. This
session will introduce the basic CRISPR/Cas9 system, explain how this
technology is being modified to allow selective inactivation, activation, and live
imaging of the genome, and illustrate how the technology can be applied to
study and treat lung diseases, including cancer.
Chairing: D. Erle, MD, San Francisco, CA
S. Albelda, MD, Philadephia, PA
N. Chandel, PhD, Chicago, IL
9:00 CRISPR: From Biology to Transformative Technology
J. Corn, PhD, Berkeley, CA
9:30 Genome-Scale CRISPR-Mediated Control of Gene Repression
and Activation
J. Weissman, PhD, San Francisco, CA
10:00 Dissecting the Role of Oxidative Homeostasis in Lung Cancer
Using CRISPR/Cas9 Genome Engineering
T. Papagiannakopoulos, PhD, New York, NY
10:30 CRISPR Tools for Complex Transcription Control and
Functional Study
S. Qi, PhD, Stanford, CA
This session and the International Conference are supported by an educational grant from
AstraZeneca LP.
All CME sessions have been planned and implemented in accordance with the Essential
Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME)
and are free of the control of commercial interests.
B6
BEHAVIORAL • CLINICAL
SCIENTIFIC SYMPOSIUM
CME Credits Available: 2.0
BUILDING E-BRIDGES: TOOLS AT OUR FINGERTIPS
FOR ENHANCING COLLABORATIVE CARE
Assemblies on Behavioral Science and Health Services Research;
Clinical Problems; Critical Care; Nursing; Thoracic Oncology
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Room 303/305 (South Building, Esplanade Level)
Target Audience
Clinicians and scientists seeking to understand developments in shared
decision-making and to explore cutting edge tools aimed at advancing
interdisciplinary, patient centered collaboration across pulmonary and critical care.
Objectives
At the conclusion of this session, the participant will be able to:
• present new findings about the complexity of shared decision-making to
enhance patient-centered care;
• apply novel, innovative tools to enrich risk communication and improve the
quality of life and health of patients;
• evaluate future directions in and barriers to collaborative, personalized care.
For most medical decisions, multiple options are available with each choice having
its own list of benefits and harms. Decisions inconsistent with patient preferences
may have unintended consequences to both patients and the health system. Shared
decision-making provides a model for personalized medicine to enhance
patient-centered care. This session will allow leading experts to discuss: (1) how
traditional communication has failed and why shared decision-making has evolved;
(2) the complexity of the decision-making process; (3) what tools are available,
across pulmonary and critical care, to enhance communication; (4) what future
directions and barriers may lie ahead in patient-centered risk communication.
Chairing: T.S. Valley, MD, Ann Arbor, MI
R.S. Wiener, MD, MPH, Boston, MA
C.E. Cox, MD, MPH, Durham, NC
9:00 A Patient’s Perspective
K. Erickson, Coral Gables, FL
9:05 Helping Me Help You: Making the Right Decision for Different
Patients
T.S. Valley, MD, Ann Arbor, MI
9:23 So You’re Telling Me There’s a Chance? Theories to Improve
Risk Communication
J.L. Hart, MD, Philadelphia, PA
MONDAY MORNING
ATS 2016 • San Francisco