Final Program

MONDAY • MAY 16 145
603 Asthma Susceptibility IL33 SNP rs4742165 Is an eQTL for
Asthmatic Serum sST2/O. Li, G. Jia, A. Dressen, B. Yaspan, R.
Beasley, J. Fingleton, C. Holweg, J. Matthews, J. Harris, H.
Scheerens, J. Arron, D. Choy, T. Staton, South San Francisco, CA,
p.A2917
604 Reduced Pulmonary Function Growth in Childhood Asthmatics
Shows High Additive Genetic Heritability/M. McGeachie, G.L.
Clemmer, D.C. Croteau-Chonka, P.J. Castaldi, M.H. Cho, J.E.
Sordillo, J. Lasky-Su, B.A. Raby, K. Tantisira, S.T. Weiss, Boston,
MA, p.A2918
605 Association of CD14 C-159t Promoter Polymorphism with
Regulatory Cytokine Response in Indian Children with Atopic
Asthma/A. Agarwal, M. Singh, A. Chauhan, N. Paul, Chandigarh,
India, p.A2919
606 Polymorphisms of IL4RA and ADAM33, Risk Variants in
Patients with Asthma Exacerbations with Type 2-Predominant
Condition/H. Sunadome, H. Matsumoto, G. Petrova, Y. Kanemitsu,
Y. Izuhara, Y. Tohda, T. Horiguchi, H. Kita, K. Kuwabara, K. Tomii,
K. Otsuka, M. Fujimura, N. Ohkura, K. Tomita, A. Yokoyama, H.
Ohnishi, Y. Nakano, T. Oguma, S. Hozawa, T. Nagasaki, I. Ito, H.
Inoue, T. Tajiri, T. Iwata, J. Ono, S. Ohta, M. Tamari, T. Hirota, T.
Yokoyama, A. Niimi, K. Izuhara, M. Mishima, Kyoto, Japan,
p.A2920
607 Genome Wide Association Study of Lung Function and Allergy
Related Traits in Subjects with Asthma/M.A. Portelli, N.D.
Bennett, I. Ntalla, A. Henry, C.K. Billington, D. Shaw, Z.E.K.
Pogson, A. Fogarty, T. McKeever, L. Jonker, A. Singapuri, L.
Heaney, A. Mansur, N.C. Thomson, R. Chaudhuri, J. Holloway, G.
Lockett, P. Howarth, J. Hankinson, R. Niven, A. Simpson, M.D.
Tobin, L.V. Wain, I.P. Hall, C.E. Brightling, I. Sayers, Nottingham,
United Kingdom, p.A2921
608 Determining the Contribution of IL33 and IL1RL1
Polymorphisms to Clinical and Immunological Features of
Asthma/M.A. Portelli, N.D. Bennett, J. Hankinson, I. Ntalla, A.
Henry, C.K. Billington, D. Shaw, Z.E.K. Pogson, A. Fogarty, T.
McKeever, L. Jonker, A. Singapuri, L. Heaney, A. Mansur, N.C.
Thomson, R. Chaudhuri, J. Holloway, G. Lockett, P. Howarth, R.
Niven, M.D. Tobin, L.V. Wain, I.P. Hall, C.E. Brightling, A. Simpson,
I. Sayers, Nottingham, United Kingdom, p.A2922
609 Where Next in Asthma Research? A Review of Current
Understanding and Future Focus to Prevent and Cure
Asthma/S. Johnston, M.R. Edwards, J. Schwarze, C. Skevaki, S.
Saglani, E.J. Kennington, J.L. Edwards, S. Walker, London, United
Kingdom, p.A2923
610 Exome Array Analysis Identifies IL27 as a Susceptibility Locus
for Chronic Obstructive Pulmonary Disease/B.D. Hobbs, M.M.
Parker, H. Chen, T. Lao, M.E. Hardin, D. Qiao, I. Hawrylkiewicz, P.
Sliwinski, J.J. Yim, W.J. Kim, D.K. Kim, P.J. Castaldi, C.P. Hersh,
J.D. Morrow, B.R. Celli, V. Pinto-Plata, G.J. Criner, N. Marchetti, R.
Bueno, A. Agusti, B.J. Make, J.D. Crapo, P. Calverley, C.F.
Donner, D.A. Lomas, E.F. Wouters, J. Vestbo, P.D. Pare, R.D.
Levy, S.I. Rennard, X. Zhou, N.M. Laird, X. Lin, T.H. Beaty, E.K.
Silverman, M.H. Cho, Boston, MA, p.A2924
611 DNA Co-Methylation Modules Associate with COPD in African
Americans/R. Busch, J.D. Morrow, J. Lasky-Su, W. Qiu, G.J.
Criner, D.L. DeMeo, Boston, MA, p.A2925
612 The Effect of Smoke Exposure on Gene Expression: From
Fetal Development to COPD/L.P. Hayden, S. Sharma, J.D.
Morrow, D. Chhabra, A. Kho, C.A. Vyhlidal, R. Gaedigk, J.S.
Leeder, G.J. Criner, R. Bueno, B. Celli, K. Tantisira, D.L. DeMeo,
S.T. Weiss, E.K. Silverman, C.P. Hersh, Boston, MA, p.A2926
613 Exome Array Analysis of Quantitative Lung Function
Measurements in the COPDGene Study/M.M. Parker, B.D.
Hobbs, R.A. Mathias, I. Ruczinski, S.M. Lutz, J.E. Hokanson, P.J.
Castaldi, J.D. Crapo, E.K. Silverman, M.H. Cho, T.H. Beaty,
Boston, MA, p.A2927
614 Genetic and Epigenetic Regulation of Myosin Light Chain
Kinase by Inflammatory Lung Disease Associated
Polymorphisms/X. Sun, V.R. Elangovan, Y. Shimizu, S.-F. Ma, T.
Wang, J.G.N. Garcia, Tucson, AZ, p.A2928
615 Greater Urban Tree Canopy Exposure May Be Linked to Asthma
and DNA Methylation of the IL4 Gene Promoter/S. Lovinsky-Desir,
G.S. Lovasi, X. Liu, D. Torrone, K.H. Jung, J. Jezioro, F.P. Perera, A.
Rundle, R.L. Miller, New York, NY, p.A2929
616 Risk Factors Associated with Irreversible Airway Obstruction
in Asthma: A Meta-Analysis and Systematic Review/L. Zhang,
Sichuan, China, p.A2930
617 The Role of Genes Identified in Genome-Wide Association
Studies of Asthma Susceptibility in the Developmental Origin
of Asthma/S. Sharma, A. Kho, C. Vyhlidal, R. Gaedigk, J.S.
Leeder, K. Tantisira, S.T. Weiss, Aurora, CO, p.A2931
618 Gene Expression Networks of Allergic Asthma as
Characterized by IgE Levels Among Costa Rican
Children/J.L.-S.A. Lasky-Su, Y. Virkud, R.S. Kelly, M. McGeachie,
D.C. Croteau-Chonka, S.T. Weiss, Boston, MA, p.A2932
619 Flow Cytometry to Generate Transcriptional Profiles from
Individual Myeloid Populations Isolated from Human Lung
Tissues/J. Walter, A.V. Misharin, A.C. Argento, A.C.
McQuattie-Pimentel, M. Chi, F.J. Gonzalez-Gonzalez, S.
Soberanes, P.A. Reyfman, V. Morgan, A. Bharat, S. Bhorade, H.R.
Perlman, J.I. Sznajder, N. Chandel, K.M. Ridge, G.S. Budinger,
Chicago, IL, p.A2933
620 Gene Expression Networks of Adult Asthma Modified by
Childhood Obesity/D.C. Croteau-Chonka, K. Tantisira, V.J. Carey,
S.T. Weiss, J. Lasky-Su, B.A. Raby, Boston, MA, p.A2934
621 Genome-wide Association Study of Asthma Susceptibility in
African American Children and Youth: The SAGE II Study/J.
Adams, M. White, O. Risse-Adams, S.S. Oh, P. Goddard, J.
Magana, M. Spear, D. Hu, S. Huntsman, C. Eng, E.G. Burchard,
San Francisco, CA, p.A2935
622 Children with an Acute Respiratory Illness Infected with
Human Rhinovirus (RV) Species C, that Have a CDHR3
rs6967330 A Allele, Are More Likely to Have a Recurrent
Wheezing Hospital Presentation/I.A. Laing, S.-K. Khoo, K.M.
Franks, F. Prastanti, J.E. Everard, S. Oo, J. Bizzintino, P.N. Le
Souef, Subiaco, Australia, p.A2936
623 Smoking-Associated Changes in DNA Methylation Are Widely
Abolished by Vitamin C Supplementation to Pregnant
Smokers/L.E. Shorey-Kendrick, C.T. McEvoy, L.J. Wilhelm, B.H.
Vuylsteke, K.F. Milner, E.R. Spindel, Beaverton, OR, p.A2937
MONDAY MORNING
ATS 2016 • San Francisco