Final Program

196 MONDAY • MAY 16
P1487
P1488
P1489
P1490
The Imbanlance of Oxidant/Antioxidant Caused by Nitrate in
Particulate of Cigarette Smoke May Influence the Progress of
Chronic Obstructive Pulmonary Disease/L. Wang, Y. Hu, H. Li,
Hangzhou, China, p.A4109
Proteasome-Dependent MHC I Antigen Presentation Is Altered
by Cigarette Smoke/I.E. Keller, A. Dann, C. Lukas, D. Brech, O.
Vosyka, E. Noessner, O. Eickelberg, S. Meiners, Munchen,
Germany, p.A4110
Quercetogetin Protects Cigarette Smoke Extract (CSE)-Induced
Mitophagic Cell Death in Pulmonary Epithelial Cells/J.-W. Park,
S. Eun Sook, Incheon, Korea, Republic of, p.A4111
Cigarette Smoke-Induced Accumulation of Oxidized
Phosphatidylcholine in COPD Primary Human Lung
Fibroblasts: Inhibition by Simvastatin/M.H. Ryu, A.D. Desautels,
A. Jha, T.H. Mahood, R. Chaudhary, H. Unruh, C. Carlsten, A.
Ravandi, A.J. Halayko, Vancouver, Canada, p.A4112
P1491 Cigarette Smoke Decreases NALP3 Protein Levels/S. Han, J.
Jerome, R. Mallampalli, Pittsburgh, PA, p.A4113
P1492
P1493
P1494
P1495
P1496
B61
Mechanisms of Uptake/Egress and Intracellular Fate of
Nanoparticles in Primary Rat Alveolar Epithelial Cell
Monolayers (RAECM)/E.D. Crandall, A. Sipos, J. Peti-Peterdi,
R.H. Chow, Z. Borok, K.-J. Kim, Los Angeles, CA, p.A4114
Toxicants, Salicylic Acid and Toluene Diisocyanate, Enhance
Carbachol-Induced Bronchoconstriction in Human
Precision-Cut Lung Slices (hPCLS)/J.A. Jude, C. Koziol-White,
G. Cao, D. Botelho, W. Jester, R.A. Panettieri, Jr., Philadelphia,
PA, p.A4115
Determination of Asbestos Body-Associated Proteins by Laser
Scanning Micro-Dissection and Mass Spectrometry/T.N.
Perkins, E. Toftgaard Poulsen, J.J. Enghild, A. Ghio, V. Roggli, T.D.
Oury, Pittsburgh, PA, p.A4116
Synthesis of a Cross-Linked Hyaluronan Matrix by the Airway
Epithelium in Experimental Bronchiolitis Obliterans/D.M. Brass,
F.L. Kelly, W.M. Gwinn, C. Brinkley, A. Nagler, D.L. Morgan, M.W.
Foster, S.M. Palmer, Durham, NC, p.A4117
Preclinical Development of an Antibody Against EMAP II to
Treat Cigarette-Smoke (CS)-Induced Emphysema/K. Koike, E.
Beatman, M. Justice, B. Johnstone, M. Clauss, K. Schweitzer, I.
Petrache, Denver, CO, p.A7843
THEMATIC POSTER SESSION
FIBROBLASTS AND MATRIX IN COPD
9:00 a.m. - 4:15 p.m. MOSCONE CENTER
Viewing: Posters will be on display for entire session.
Area H, Hall D (North Building, Lower Level)
Discussion: 11:00-11:45: authors will be present for individual discussion
11:45-12:45: authors will be present for discussion with assigned facilitators
P1019
Combination of Glycopyrronium and Indacaterol Suppressed
Carbachol-Induced Fibrotic Responses in Lung Fibroblasts/Y.
Namba, S. Togo, M. Traf, K. Kadoya, K.Y. Nagahama, H. Taka, N.
Kaga, A. Orimo, X. Liu, K. Takahashi, Tokyo, Japan, p.A4118
P1020
P1021
Role of Growth Differentiation Factor 11 in the Pathogenesis of
Chronic Obstructive Pulmonary Disease/K. Onodera, H.
Sugiura, M. Yamada, A. Koarai, S. Togo, T. Numakura, R. Tanaka,
K. Sato, Y. Hashimoto, K. Abe, Y. Kyogoku, M. Ichinose, Sendai,
Japan, p.A4119
The Association Between Emphysema and Genetic Variations
of LTBP4, a Protein Related to the Formation of Elastic Fiber
Assembly/T. Ishii, S. Chubachi, M. Sasaki, T. Arai, T. Betsuyaku,
A. Gemma, K. Kida, Tokyo, Japan, p.A4120
P1022 Fibroblast Growth Factor 23-Mediated FGF Receptor 4
Signaling in Bronchial Epithelial Cells Contributes to
Inflammation in COPD Patients/S. Krick, N. Baumlin, S. Dennis,
M. Campos, C. Faul, M. Salathe, Miami, FL, p.A4121
P1023
P1024
P1025
P1026
P1027
P1028
P1029
P1030
P1031
P1032
Extracellular Matrix Components Affect Myoblast Proliferation
and Differentiation/X. Liu, Z. Song, J. Ren, A. Nelson, F. Makino,
H. Basma, S. Swanson, I. Pipinos, S.I. Rennard, Omaha, NE,
p.A4122
Extracellular Vesicles (EVs) from Normal Human Lung
Fibroblasts Cells (NHLF) and COPD/Pulmonary Emphysema
Cells Stimulated by IL-b/TNF-a Mediate Divergent Effects/
F. Makino, J. Ikari, M. Makino, A. Nelson, H. Basma, X. Liu, S.I.
Rennard, Omaha, NE, p.A4123
Prenyltransferase Expression and Function in Lung
Fibroblasts from Moderate COPD Patients/T.H. Mahood, M.H.
Ryu, A. Desautels, O.O. Ojo, G.L. Stelmack, H. Unruh, A.J.
Halayko, Winnipeg, Canada, p.A4124
Role of Transforming Growth Factor -b1 and Smad Signaling
Pathways in EMT Associated COPD Pathegenesis in
Smokers/M.Q. Mahmood, D. Reid, H.K. Muller, D.A. Knight, S.S.
Sohal, E.H. Walters, Hobart, Australia, p.A4125
Differential Expression of mRNAs in COPD Lung Fibroblasts
Varies with Cell Passage and Inflammatory Stimulation In
Vitro/J. Ikari, A. Nelson, L. Smith, T.D. LeVan, S. Iwasawa, Y.
Gunji, F. Makino, K. Ikari, M. Farid, X. Wang, H. Basma, X. Liu,
D.L. DeMeo, C. Feghali-Bostwick, K. Tatsumi, S.I. Rennard,
Omaha, NE, p.A4126
Regulation of Non-Canonical WNT-5A by Primary Human Lung
Fibroblasts/F. Ciolek, M. Konigshoff, H.A. Baarsma, Munich,
Germany, p.A4127
Priming Adipose Stromal Cells for Enhanced Paracrine
Anti-Elastase Activity/K. Ni, M.U. Mukhtar, C. Meador, D. Cao, M.
Justice, K. Schweitzer, K.L. March, I. Petrache, Denver, CO,
p.A4128
Elastin Degradation of Lung Matrix in Advanced COPD
Compared to Normal Lung/Y.Y. Lin, J. He, S. Ma, J. Cantor, T.
Usuki, G.M. Turino, New York, NY, p.A4129
PPARg and TGF-b1 Signaling Are Involved in Airway Repair in
Cigarette Smoke-Associated Chronic Bronchitis/J. Sailland, N.
Baumlin, S. Dennis, S. Krick, M. Salathe, A. Schmid, Miami, FL,
p.A4130
Epigenetic Changes in CSE-Exposed Human Lung Fibroblasts/
H. Basma, G. Blankenau, A. Nelson, F. Makino, X. Liu, L. Smith,
S.I. Rennard, Omaha, NE, p.A4131
ATS 2016 • San Francisco