Final Program

246 TUESDAY • MAY 17
415 Investigating mRNA and miRNA Alterations Induced by
Asthma-associated Cytokine Stimulation in a Human Airway
Model Using RNASeq/L.R. Bonser, S.A. Christenson, J. Pollack,
R. Barbeau, A. Barczak, L. Zlock, W. Finkbeiner, P.G. Woodruff, D.
Erle, San Francisco, CA, p.A4624
416 Lung Gene Expression Analysis: An Integrative Web Portal for
Comprehensive Gene Expression Data Analysis in Lung
Development/Y. Du, J.A. Kitzmiller, A. Sridharan, A.K. Perl, J.
Bridges, R.S. Misra, G.S. Pryhuber, T.J. Mariani, S. Bhattacharya,
M. Guo, S.S. Potter, P. Dexheimer, B. Aronow, J.A. Whitsett, Y. Xu,
Cincinnati, OH, p.A4625
417 A Comparative Transcriptomic Approach to Identify
Transcriptional Programs Regulating Primate Lung
Maturation/Y. Xu, Y. Du, J.A. Kitzmiller, A. Sridharan, S.S. Potter,
S.E. Wert, M. Guo, A. Jobe, S.G. Kallapur, C.A. Chougnet, J.A.
Whitsett, Cincinnati, OH, p.A4626
418 MicroRNA Array Analysis of Microvesicles (MVs) Derived from
Broncho-Alveolar Lavage Fluid (BALF) Indicates Potential
Novel Regulators of Lipopolysaccharide (LPS) Induced
Alveolar Macrophage Activation/D. Zhang, H. Lee, Y. Jin,
Boston, MA, p.A4627
419 Gene Expression Profiles Using RNA-Sequencing of
Formalin-Fixed, Paraffin-Embedded (FFPE) Lung Tissue
Predict Poor Outcomes in Idiopathic Pulmonary Fibrosis/J.
Herazo-Maya, M. Vukmirovic, X. Yan, B. Hu, R. Homer, B.
Juan-Guardela, Q. Li, A.E. Tzouvelekis, G. Yu, F. Ahangari, N.
Aurelien, G. Deluliis, K. Gibson, K.O. Lindell, S.A. Yousem, N.
Kaminski, New Haven, CT, p.A4628
420 Single Cell RNA Sequencing Reveals Smoking-Associated
Alterations in Bronchial Epithelial Subpopulations/G.E. Duclos,
J.D. Campbell, P. Autissier, Y.M. Dumas, R. Terrano, G. Liu, M.E.
Lenburg, A. Spira, J. Beane, Boston, MA, p.A4629
421 Obese Adipocyte-Derived Exosomal miRNAs Targeting TGF-ß
Signaling Are Associated with Poor Asthma Control/S.C.
Ferrante, S. Epstein, E. Nadler, M. Barberio, M. Goldberg, L. Maltz,
M. Hubal, R.J. Freishtat, Washington, DC, p.A4630
422 Corticosteroid Effects on Transcriptional Programs Regulating
Lung Maturation in the Fetal Primate/D.D. Lipps, A. Schmidt, A.
Jobe, J.A. Whitsett, Y. Xu, Cincinnati, OH, p.A4631
423 Non-Invasive Sub-Phenotyping of Asthma in the U-BIOPRED
Study by Analysis of Urinary Lipid Mediator Excretion
Patterns/C.E. Wheelock, J. Kolmert, D. Lefaudeux, M. Sjodin, D.
Balgoma, A.R. Sousa, J. Corfield, I. Pandis, R. Djukanovic, S.-E.
Dahlen, Stockholm, Sweden, p.A4632
424 Interrogation of an Exhaled microRNA Panel to Develop Risk
Biomarkers for Lung Cancer/S.D. Spivack, M. Shi, W. Han, L.
Rosa, Bronx, NY, p.A4633
C22
POSTER DISCUSSION SESSION
AIRWAY EPITHELIUM: MOLECULAR REGULATION
OF INFLAMMATION
9:00 a.m. - 11:00 a.m. MOSCONE CENTER
Room 133 (North Building, Lower Level)
Poster Viewing 9:00-9:45
Discussion 9:45-11:00
Chairing: R. Wu, PhD, Davis, CA
A. Haczku, MD, PhD, Davis, CA
A. Van Der Vliet, PhD, Burlington, VT
101 Allergen-Induced Unfolded Protein Response Regulates Lung
Inflammation and Fibrosis/V. Anathy, S. Mariswamy, E. Nakada,
B. Mihavics, S.M. Hoffman, D.G. Chapman, N.R. Bhakta, P.G.
Woodruff, C.G. Irvin, A.E. Dixon, M.E. Poynter, Burlington, VT,
p.A4634
102 Adaptive and Innate Lymphocytes Are Dispensable for House
Dust Mite Induced Airways Epithelial Endoplasmic Reticulum
(ER) Stress and Fibrosis in Mice/V. Anathy, S.M. Hoffman, J.
Ather, B. Mihavics, E. Nakada, K. Fortner, M.E. Poynter, Burlington,
VT, p.A4635
103 Proteome Profiling Reveals Cofilin-1 as a Candidate Mediator
of TGF-Beta1-Induced Glucocorticoid Resistance/A.G. Stewart,
C.R. Keenan, Y.C. Xia, S. Langenbach, M. Li, Parkville, Australia,
p.A4636
104 Respiratory Syncytial Virus or the TLR3 Ligand, Double
Stranded RNA, Induce Glucocorticoid Resistance in Human
Bronchial Epithelial Cells/A.G. Stewart, A. Radwan, Y.C. Xia, S.
Langenbach, R.C. Gualano, Parkville, Australia, p.A4637
105 Respiratory Syncytial Virus or the TLR3 Ligand Double
Stranded RNA Induce Glucocorticoid Resistance in Human
Bronchial Epithelial Cells/A. Radwan, Y.C. Xia, S. Langenbach,
R.C. Gualano, A.G. Stewart, Parkville, Australia, p.A4638
106 Distinct MUC5AC-Rich Domains in Mucus Tether to the
Epithelium and Impair Mucociliary Transport in Asthma/L.R.
Bonser, L. Zlock, W. Finkbeiner, D. Erle, San Francisco, CA,
p.A4639
107 Insulin Mediated Airway Remodeling Via ß Catenin Signaling/
P. Kolumam Parameswaran, M. Bodas, S. Singh, M.R. Freeman,
M.A. Thompson, N. Bhatraju, B. Patnaik, A. Gheware, U.
Mahabalirajan, R. Gosens, B. Ghosh, C. Pabelick, A. Linneberg,
Y.S. Prakash, A. Agarwal, Rochester, MN, p.A4640
108 An In Vivo Model of Human Airways for Investigating
Fibrosis/S.C. Ferrante, T.-L. Hackett, C.E. Hoptay, J. Engelhardt,
J.L. Ingram, S. Alcala, Y. Zhang, F. Shaheen, E. Matz, D.K. Pillai,
R.J. Freishtat, Washington, DC, p.A4641
109 SPLUNC1 Modulates Calcium Influx in Airway Smooth
Muscle/T. Wu, W. Walton, M. Redinbo, N.E. Alexis, R. Tarran,
Chapel Hill, NC, p.A4642
ATS 2016 • San Francisco