Final Program

MONDAY • MAY 16 197
P1033
P1034
P1035
P1036
P1037
B62
Connective Tissue Growth Factor that Promotes Pulmonary
Epithelial Cell Senescence Is a Severity-Dependent Biomarker
for COPD/J.-H. Jang, H. Chand, S. Bruse, M. Doyle-Eisele, C.
Royer, J. McDonald, Y. Lin, Y. Tesfaigzi, T. Nyunoya, Albuquerque,
NM, p.A4132
Little Evidence for Epithelial-Mesenchymal Transition in a
Murine Model of Airway Fibrosis Induced by Repeated
Naphthalene Exposure/T. Tsuji, M. Itoh, R. Kikuchi, T. Uruma, H.
Watanabe, K. Yamaguchi, H. Nakamura, K. Aoshiba, Tokyo, Japan,
p.A4133
Low Vitamin K Status Is Associated with COPD and
Accelerated Degradation of Mature Elastin/B. De Brouwer, M.
Spanbroek, N. Drummen, J. Van Den Ouweland, P. Zanen, C.
Vermeer, R. Janssen, Nijmegen, Netherlands, p.A4134
Relationship Between Pulmonary Matrix Metalloproteinases
and Emphysema Sub-Types/K. Ostridge, S. Harden, S. Bourne,
N. Coombes, R.S.J. Estepar, G. Washko, P. Elkington, K.J.
Staples, T.M.A. Wilkinson, Southampton Hampshire, United
Kingdom, p.A4135
Matrix Metalloproteinase 10 (MMP10) Is Highly Up-Regulated in
M2 Macrophages and Lymphoid Aggregates in Idiopathic
Pulmonary Fibrosis/C. Chima-Melton, H.D. Jones, W. Parks, Los
Angeles, CA, p.A7844
THEMATIC POSTER SESSION
THE BIOLOGY OF SCARRING. WHERE ARE WE
NOW
9:00 a.m. - 4:15 p.m. MOSCONE CENTER
Viewing: Posters will be on display for entire session.
Area M, Hall D (North Building, Lower Level)
Discussion: 11:00-11:45: authors will be present for individual discussion
11:45-12:45: authors will be present for discussion with assigned facilitators
P1498
P1499
P1500
P1501
Hypoxia Worsens Pulmonary Fibrosis Through Expression of
C/EBP Homologous Protein (CHOP)/A. Burman, W.E. Lawson,
T.S. Blackwell, H. Tanjore, Nashville, TN, p.A4136
Expression of the Relaxin Receptor RXFP1 Is Decreased in
Idiopathic Pulmonary Fibrosis: Implications for Relaxin-Based
Therapies in Fibrotic Lung Disease/J. Tan, J. Tedrow, Y. Chu, K.
Veraldi, Y. Zhang, D. Kass, Pittsburgh, PA, p.A4137
Low Input Ion Torrent RNA-Sequencing of Formalin-Fixed,
Paraffin-Embedded (FFPE) Lung Tissue from Patients with
Idiopathic Pulmonary Fibrosis/M. Vukmirovic, X. Yan, B. Hu, R.
Homer, G. Deluliis, K. Gibson, K.O. Lindell, S.A. Yousem, J.H.
Maya, N. Kaminski, New Haven, CT, p.A4138
Integrin-a6 Regulates Cellular Senescence and Pro-fibrotic
Gene Expression in IPF Fibroblasts/A.R. Kurundkar, J.S.
Deshane, Y. Zhou, D. Kurundkar, L. Hecker, S. Rangarajan, V.J.
Thannickal, Birmingham, AL, p.A4139
P1502
P1503
P1504
P1505
P1506
P1507
P1508
P1509
P1510
P1511
P1512
P1513
An Antagonistically Pleiotropic Role of miR-34a in the
Pathogenesis of Lung Fibrosis in Young and Aged Mice/H. Cui,
S. Banerjee, J. Ge, N. Xie, R.-M. Liu, V.B. Antony, V.J. Thannickal,
G. Liu, Birmingham, AL, p.A4140
Elderly-Onset Hereditary Pulmonary Alveolar Proteinosis and
CSF2RA Mutation/R. Tazawa, M. Ito, K. Nakagome, K. Akasaka,
H. Ohta, Y. Uchida, A. Shiono, T. Takada, M. Nagata, J. Tohyama,
K. Hagiwara, M. Kanazawa, K. Nakata, Niigata, Japan, p.A4141
FENDRR Is an Epigenetic Regulator of Cellular Senescence in
Pulmonary Fibroblasts/K. Sakamoto, B. Juan Guardela, G. Yu, J.
Herazo-Maya, F. Ahangari, A.E. Tzouvelekis, R. Homer, N.
Kaminski, New Haven, CT, p.A4142
Analysis of Long Non-Coding RNA Expression Profiles in the
Mouse Model of Pulmonary Fibrosis/H. Sun, J. Chen, W. Qian, J.
Kang, J. Wang, L. Jiang, L. Qiao, J. Zhang, Nanjing, China,
p.A4143
Identification of Paraquat Aerosolization-Induced Lung Injury
and Related Fibrosis in Mice/H. Sun, J. Kang, P. Huang, C.E.
Hennessy, L.A. Warg, S.K. Mathai, M.I. Schwarz, C.M. Evans, I.V.
Yang, D.A. Schwartz, J. Zhang, Nanjing, China, p.A4144
NEU1 Sialidase Is Elevated in the Lungs of Patients with IPF
and Contributes to Fibrosis/I.G. Luzina, V. Lockatell, S.W. Hyun,
Z. Noor, A. Liu, E.P. Lillehoj, C. Lee, A. Miranda-Ribera, N.W.
Todd, S.E. Goldblum, S.P. Atamas, Baltimore, MD, p.A4145
Interstitial Smooth Muscle Bundles Rather than Activated
Myofibroblasts Are Associated with Poor Clinical Outcomes in
Patients with Histologic Areas of Organization/I.G. Luzina, A.E.
Wyman, A.P. Burke, S.P. Atamas, N.W. Todd, Baltimore, MD,
p.A4146
Increased Alveolar Epithelial Cell Senescence in Pulmonary
Fibrosis/M. Lehmann, K. Mutze, H.B. Schiller, D.E. Wagner, M.
Konigshoff, Munich, Germany, p.A4147
Gene Expression Profiling in End-Stage IPF Lung Fibrotic
Microenvironment/J.E. McDonough, F. Ahangari, M. Vukmirovic,
G. Deluliis, N. Tanabe, S. Verleden, J. Herazo-Maya, X. Yang, B.
Hu, N. Aurelien, G.M. Verleden, B.M. Vanaudenaerde, W. Wuyts,
J.C. Hogg, N. Kaminski, Leuven, Belgium, p.A4148
Role of MAP Kinase Phosphatase 5 (MKP5) in Pulmonary
Fibrosis/A.E. Tzouvelekis, G. Yu, M. Kisuk, J. Herazo-Maya, T.
Woolard, N. Aurelien, M. Vukmirovic, K. Sakamoto, T. Adams, G.
DeIuliis, F. Ahangari, A. Bennett, N. Kaminski, New Haven, CT,
p.A4149
Disruption of Proximal-Peripheral Epithelial Differentiation and
Activation of Hippo/YAP Signaling in Idiopathic Pulmonary
Fibrosis/A. Sridharan, A.W. Lange, K.A. Wikenheiser-Brokamp, B.
Stripp, J.A. Whitsett, Cincinnati, OH, p.A4150
STAT3 IS a Critical Regulator of Myofibroblast Function and
Pulmonary Fibrosis/K.M. Choi, A.J. Haak, K.J. Smith, P.R.
Walters, M.A. Thompson, M.R. Freeman, L.J. Manlove, Y.S.
Prakash, R. Vassallo, D.J. Tschumperlin, Rochester, MN, p.A4151
MONDAY MORNING
ATS 2016 • San Francisco