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256 TUESDAY • MAY 17<br />

P383<br />

P384<br />

P385<br />

P386<br />

P387<br />

P388<br />

C32<br />

The Group Which Elevated Exhaled Nitric Oxide Exists in<br />

Normal Population/M. Itoga, S. Takanashi, Y. Tanaka, H. Tanaka,<br />

K. Taima, T. Morimoto, K. Okumura, Hirosaki, Japan, p.A4847<br />

Identification of a Spleen Tyrosine Kinase (Syk) Inhibitor from<br />

Screening Brusatol Derivatives and Investigation of Its<br />

Anti-Airway Inflammatory Mechanisms/Q. Hou, Y. Ding, J. Bai,<br />

M. Lin, China, p.A4848<br />

Dermatophagoides Pteronyssinus 1 and Dermatophagoides<br />

Pteronyssinus 2 Specific Immunoblobulins E Curative Effect<br />

Evaluation for Specific Immunotherapy/P. Zheng, B. Sun,<br />

Guangzhou, China, p.A4849<br />

The Cardiomyocyte Protein Alpha-T-Catenin Contributes to<br />

Asthma Through Regulating Pulmonary Vein Inflammation/C.J.<br />

Gottardi, G.R.S. Budinger, P. Bryce, S.S. Folmsbee, Chicago, IL,<br />

p.A4850<br />

Preventative Administration of IL-27 Improves Airway<br />

Inflammation of Ovalbumin -Induced Asthma Mice Model Via<br />

Both STAT1 and GADD45g/p38MAPK Pathways/Z. Chen, X. Su,<br />

K. Xu, J. Pan, X. Wang, Shanghai, China, p.A4851<br />

A Microfluidic Small Airway-on-Chip Enables Analysis of<br />

Human Lung Inflammation and Therapeutic Responses In<br />

Vitro/R. Villenave, K. Benam, C. Lucchesi, A. Varone, C. Hubeau,<br />

H.H. Lee, S. Alves, M. Salmon, T. Ferrante, J. Weaver, A. Bahinski,<br />

G. Hamilton, D.E. Ingber, Boston, MA, p.A7869<br />

THEMATIC POSTER SESSION<br />

IMAGING INFLAMMATION IN THE LUNG<br />

9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />

Viewing: Posters will be on display for entire session.<br />

Area B, Hall D (North Building, Lower Level)<br />

Discussion: 11:00-11:45: authors will be present for individual discussion<br />

11:45-12:45: authors will be present for discussion with assigned facilitators<br />

Facilitator:<br />

P135<br />

P136<br />

P137<br />

A.J. Gow, PhD, Piscataway, NJ<br />

Use of Radiolabelled Autologous Neutrophils to Measure<br />

Neutrophil Clearance in the Lung in Patients with COPD and in<br />

Healthy Subjects Following Lipopolysaccharide/N.C. Tregay, N.<br />

Farahi, R. Simmonds, C. Loutsios, I. Cullum, D. Gillett, D. Carroll,<br />

K. McGlashan, L. Griffiths, S. Madhavan, M. Begg, A. Cahn, E.<br />

Hessell, K. Povey, C. Solanki, J. Buscombe, A.M. Peters, E.R.<br />

Chilvers, Cambridge, United Kingdom, p.A4852<br />

Mapping and Analysis of Human and Mouse Esophageal Nerve<br />

Plexuses Using Whole Mount Immunofluorence Imaging<br />

Reveals Differences in Neuropeptide Expression/B.J. Marsh,<br />

M.G. Drake, A.D. Fryer, D.B. Jacoby, Portland, OR, p.A4853<br />

Static 18F-FDG-PET Scans and Patlak Analysis of Dynamic<br />

18F-FDG-PET Scans for Quantification of Lung Inflammation in<br />

Experimental ARDS/A. Braune, L. Oehme, T. Kiss, T. Bluth, J.<br />

Kotzerke, M.G.D. Abreu, Dresden, Germany, p.A4854<br />

P138<br />

P139<br />

P140<br />

C33<br />

Ultrastructural Changes and Mitochondrial Dysfunction in<br />

Primary Human Airway Epithelial Cells (HBECs) from Subjects<br />

with Asthma/D.E. Winnica, M. Bueno, M. Sullivan, C. Corey, A.L.<br />

Mora, D. Stolz, S. Shiva, F. Holguin, Pittsburgh, PA, p.A4855<br />

Nitrogen Mustard-Induced Lung Fibrosis Visualized by MRI<br />

and CT Imaging Is Accompanied by Accumulation of Foamy<br />

Macrophages/A.J. Gow, A. Venosa, D. Adler, J. Laskin, E.<br />

Yurkow, D. Laskin, Piscataway, NJ, p.A4856<br />

Hyperleukocytic Acute Myeloid Leukemia: Radiographic<br />

Findings and Clinico-Radiological Correlation in a Large<br />

Series of Patients/M. Stefanski, C. Jamis-Dow, A. Van De Louw,<br />

Hershey, PA, p.A4857<br />

THEMATIC POSTER SESSION<br />

IMMUNE PATHOLOGY OF VIRAL INFECTIONS<br />

9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />

Viewing: Posters will be on display for entire session.<br />

Area B, Hall D (North Building, Lower Level)<br />

Discussion: 11:00-11:45: authors will be present for individual discussion<br />

11:45-12:45: authors will be present for discussion with assigned facilitators<br />

Facilitator:<br />

P144<br />

P145<br />

P146<br />

P147<br />

P148<br />

P149<br />

P150<br />

B.Y. Besecker, MD, Columbus, OH<br />

Role of Endogenous Hydrogen Sulfide in Airway<br />

Hyperresponsiveness (AHR) and Inflammation in a Mouse<br />

Model of Cigarette Smoke Exposure and Respiratory Syncytial<br />

Virus (RSV) Infection/R.P. Garofalo, Galveston, TX, p.A4858<br />

The Role of BRP-39 in RSV-Induced Airway Inflammation in<br />

Mice/M.J. Kim, D.H. Shim, I.S. Seol, S.H. Yoon, Y.H. Kim, M.N.<br />

Kim, J.Y. Hong, K.E. Lee, K.W. Kim, M.H. Sohn, K.-E. Kim, J.M.<br />

Lee, Seoul, Korea, Republic of, p.A4859<br />

Silver Nanoparticles Down-Regulate Retinoic Acid-Inducible<br />

Gen 1 (RIG-I) Signalling Pathway During Influenza Infection<br />

Resulting in Lower Activation of TANK-Binding Kinase 1<br />

(TBK1) and Reduced CCL5 Production/I. Garcia-Verdugo, A.<br />

Dieu, B. Villeret, B. Solhonne, J.-M. Sallenave, Paris, France,<br />

p.A4860<br />

HIV Infection Model of COPD in Mice/P. Geraghty, E. Hadas,<br />

B.-H. Kim, D. Volsky, R. Foronjy, New York, NY, p.A4861<br />

Immunopathology of the Airways in Severe Influenza A<br />

(H1N1)pdm Infection/M. Buttignol, R.C. Pires-Neto, R.C. Rossi E<br />

Silva, M. Ballarin, M. Dolhnikoff, T. Mauad, Sao Paulo, Brazil, p.A4862<br />

Cigarette Smoke Dampens Anti-Viral Responses in Human<br />

Small Airway Epithelial Cells Increasing Susceptibility to<br />

Influenza Viral Infections/P.F. Duffney, C.E. McCarthy, A.<br />

Nogales, T.H. Thatcher, L. Martinez-Sobrido, R.P. Phipps, P.J.<br />

Sime, Rochester, NY, p.A4863<br />

Detrimental Role of IL-1ß in a Mouse Model of Cigarette Smoke<br />

and H1N1 Influenza Infection/G. Vanderstocken, M.C. Morissette,<br />

P. Shen, A.B. Roos, A.J. Beaulieu, A. Tabuchi, W.M. Kuebler, M.R.<br />

Stampfli, Hamilton, Canada, p.A4864<br />

ATS 2016 • San Francisco

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