Final Program

226 MONDAY • MAY 16
113 COPD Subtype Identification in the International COPD
Genetics Consortium: Collaborative Subtyping Results Across
Ten Cohorts/P.J. Castaldi, M. Benet-Mora, H. Petersen, M. Preethi
Boorgula, J. Finigan, M. Paoletti, M. Boezen, J.M. Vonk, R.P.
Bowler, A. Agusti, M. Pistolesi, M.A. Puhan, G. Ter Riet, E.
Wauters, J. Anto, M.H. Cho, C.P. Hersh, K. Barnes, S.I. Rennard,
N. Rafaels, J.D. Crapo, Y. Tesfaigzi, E.K. Silverman, J.
Garcia-Aymerich, Boston, MA, p.A4439
114 TH17 Cytokine Expression Within the First 6 Months Post WTC
Exposure Is Associated with Accelerated FEV1 Decline Over
the Subsequent 13 Years/J. Weakley, C.B. Hall, R. Zeig-Owens,
T. Schwartz, M.P. Webber, M. Vossbrinck, H.W. Cohen, T.K.
Aldrich, A. Nolan, D.J. Prezant, M.D. Weiden, Brooklyn, NY,
p.A4440
115 Validation of Metabolic Syndrome Biomarkers of Particulate
Induced Lung Injury in World Trade Center Exposed Firefighters/
S. Kwon, E.J. Caraher, S.H. Haider, T. Schwartz, R. Zeig-Owens, M.P.
Webber, D. Prezant, A. Nolan, New York, NY, p.A4441
116 Traffic Related Particulate Matter and Elevated CRP in
COPD/E. Garshick, S. Grady, J.E. Hart, M.L. Moy, B. Coull, J.
Schwartz, F. Laden, P. Koutrakis, West Roxbury, MA, p.A4442
117 Smoking Duration Alone Predicts Emphysema and Lung
Function Better than Pack-Years/S.P. Bhatt, Y.-I. Kim, K.F.
Harrington, J.M. Wells, J.E. Hokanson, S.M. Lutz, M.H. Cho, D.L.
DeMeo, B.J. Make, S.I. Rennard, D.P. Tashkin, R.A. Wise, M.T.
Dransfield, W.C. Bailey, Birmingham, AL, p.A4443
118 A Population Based Assessment of Asthma and the Asthma
Chronic Obstructive Pulmonary Disease Overlap Syndrome
(ACOS): A Canadian Perspective/R. Nantel-Smith, R. Olivenstein,
J.G. Martin, J.M. FitzGerald, W.C. Tan, S.D. Aaron, J. Road, D.E.
O’Donnell, F. Maltais, P. Hernandez, R. Cowie, K.R. Chapman, D.
Marciniuk, J. Bourbeau, Montreal, Canada, p.A4444
119 Inflammatory Bowel Disease and Risk of Mortality in Chronic
Obstructive Pulmonary Disease (COPD) and Asthma-COPD
Overlap Syndrome (ACOS)/P. Brassard, M. Vutcovici, P. Ernst, A.
Kezouh, S. Suissa, A. Bitton, Montreal, Canada, p.A4445
120 Associations Between Household Air Pollution and
Cardiopulmonary Outcomes May Differ by Type of Pollutant/B.
Wills, E. Klasen, N. Naithani, R.H. Gilman, J.M. Tielsch, M. Chiang,
S. Khatry, P. N Breysse, D. Menya, C. Apaka, J. Carter, C. B
Sherman, W. Checkley, Baltimore, MD, p.A4447
121 Gender Differences by Age In Symptoms, Airflow Limitation,
Exacerbation Risk and GOLD Combined Assessment Among
Subjects with COPD in COPDGene Cohort/D.L. DeMeo, M.K. Han,
E.A. Regan, A. Yadao, A. Kavati, A. Vegesna, D. Keininger, T.K.
Wilcox, S. Ramagopalan, M. Pereira, B.J. Make, Boston, MA, p.A4448
122 Reproductive and Hormone-Related Factors Are Associated
with Lower Lung Function in COPDGene/D.L. DeMeo, M.G.
Foreman, E.A. Regan, S.P. Bhatt, M.K. Han, J. Hokanson, J.D.
Crapo, E.K. Silverman, B.J. Make, Boston, MA, p.A4449
123 Morbidity, Mortality and Lung Function in 14 Extracellular
Superoxide Dismutase R213G Homozygotes Among 95,873
Individuals from the General Population/C.J. Kobylecki, S. Afzal,
B. Nordestgaard, Herlev, Denmark, p.A4450
124 Circulating Biomarkers of Smoking and Lung Function
Deficits/M.M. Vasquez, M. Zhou, M. Imboden, D. Keidel, M.W.
Gerbase, N.M. Probst-Hensch, D.L. Sherrill, F.D. Martinez, M.
Halonen, S. Guerra, Tucson, AZ, p.A7854
B106
POSTER DISCUSSION SESSION
CELLULAR/MOLECULAR MECHANISMS AND
TRANSLATIONAL ASPECTS OF RESPIRATORY
TRACT INFECTIONS
2:15 p.m. - 4:15 p.m. MOSCONE CENTER
Room 3014 (West Building, Level 3)
Poster Viewing 2:15-3:00
Discussion 3:00-4:15
Chairing: J.P. Mizgerd, ScD, Boston, MA
D.J. Marchant, PhD, Edmonton, Canada
S. Awasthi, PhD, Oklahoma City, OK
901 Peroxisome Proliferator-Activated Receptor Gamma Activation
Attenuates Alcohol-Induced Alveolar Macrophage
Mitochondrial Derangements and Phagocytic Dysfunction via
miR-92a/b Up-Regulation/S.M. Yeligar, F.L. Harris, L.A.S. Brown,
C.M. Hart, Decatur, GA, p.A4451
902 Next Generation Sequencing of Respiratory Fluids Accurately
Distinguishes Bacterial from Viral Lower Respiratory Tract
Infection by Both Microbial and Host Transcriptional
Profiling/C. Langelier, S. Christenson, B. O’Donovan, S. Nerella,
M.K. Sontag, K. Harris, P.M. Mourani, J. DeRisi, San Francisco,
CA, p.A4452
903 Use of Bronchoalveolar Lavage Fluid as Culture Medium:
Bacterial Growth is Enhanced in Lavage Fluid Acquired from
Patients with Advanced Lung Disease/D.G. Dunlap, N.
Falkowski, E. Hunter, J.R. Erb-Downward, N. Walker, V. Lama,
G.B. Huffnagle, R.P. Dickson, Ann Arbor, MI, p.A4453
904 Synergistic Toll-Like Receptor Signaling-Induced Resistance
Protects Mice Against Pneumonia in the Presence of Acute
Leukemia and Cytotoxic Chemotherapy/M.M. Leiva-Juarez, H.H.
Ware, V.V. Kulkarni, C.T. Kirkpatrick, Y. Wang, S.E. Evans,
Houston, TX, p.A4454
905 The Role of Pellino-1 in Modulating Signalling Pathways
Controlling the Inflammatory Response to Viral Stimuli in
Airway Epithelial Cells/E.K. Marsh, E.C. Prestwich, H.M. Marriott,
C. Paiva, J.A. Bennett, M.R. Jonker, W. Timens, I.H. Heijink, L.C.
Parker, D.H. Dockrell, I. Sabroe, Sheffield, United Kingdom,
p.A4455
906 Lung Epithelial Cell Mitochondrial Reactive Oxygen Species
Are Required for Antiviral Resistance Induced by Synergistic
Toll-Like Receptor Signaling/C.T. Kirkpatrick, Y. Wang, V.V.
Kulkarni, H.H. Ware, A.K. Plumer, M.M. Leiva-Juarez, S.E. Evans,
Houston, TX, p.A4456
ATS 2016 • San Francisco