142 MONDAY • MAY 16 10:15 Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure: Results of the SERVE-HF On-Treatment Analysis/H. Woehrle, M. Cowie, C. Zu Eulenburg, C. Angermann, M.-P. D’Ortho, E. Erdmann, P. Levy, A. Simonds, F. Zannad, H. Teschler, V. Somers, K. Wegscheider, Martinsried, Germany, p.A2867 10:30 Fluticasone Furoate, Alone or in Combination with Vilanterol, Decreases the Rate of FEV1 Decline in Patients with Moderate Airflow Obstruction: SUMMIT Study/B. Celli, F.J. Martinez, J. Anderson, R. Brook, C. Crim, S. Kilbride, D.E. Newby, J. Vestbo, J. Yates, P.M.A. Calverley, Boston, MA, p.A2868 10:45 Efficacy of Endobronchial Coil Implantation in Patients with Advanced Emphysema: Results of the RENEW Trial/F.C. Sciurba, G. Criner, C.B. Strange, P.L. Shah, G.C. Michaud, A.C. Mehta, D.-J. Slebos, Pittsburgh, PA, p.A2869 B15 MINI SYMPOSIUM HEALTH EFFECTS OF INDOOR/OUTDOOR POLLUTION IN CHILDHOOD 9:00 a.m. - 11:00 a.m. MOSCONE CENTER Chairing: K.E. Pinkerton, PhD, Davis, CA R.J. Laumbach, MD, MPH, Piscataway, NJ I. Jaspers, PhD, Chapel Hill, NC Oral Presentations Room 2006/2008 (West Building, Level 2) 9:00 Innate Lymphoid Cells Mediate Type-2 Immunity in the Lungs of Ozone-Exposed Mice/J.R. Harkema, K. Kumagai, D.N. Jackson-Humbles, R.P. Lewandowski, N. Li, J.G. Wagner, East Lansing, MI, p.A2870 9:15 Proximity to Roadway, Lifetime Pollution Exposure and Asthma Risk in a Pediatric Cohort/M.B. Rice, S.L. Rifas-Shiman, A.A. Litonjua, E. Oken, M.W. Gillman, I. Kloog, H. Gibson, B. Coull, J. Schwartz, P. Koutrakis, M.A. Mittleman, D.R. Gold, Boston, MA, p.A2871 9:30 Effects of Wood Smoke Exposure on Nasal Mucosal Host Defense Responses After Infection with Live-Attenuated Influenza Virus/I. Jaspers, E.P. Pawlak, K. Addo, C. Diamond, A. Speen, C. Robinette, T.L. Noah, Chapel Hill, NC, p.A2872 9:45 Exposure to Transition Metals in Particulate Matter Air Pollution and Children’s Lung Function in the Southern California Children’s Health Study/R. Urman, R. Habre, S. Fruin, J. Gauderman, F. Lurmann, F. Gilliland, R. McConnell, Los Angeles, CA, p.A2873 10:00 Dung Biomass Smoke Attenuates Innate Immune Responses to a Viral Mimetic and Influenza A Virus in Human Small Airway Epithelial Cells/C.E. McCarthy, P.F. Duffney, T.H. Thatcher, R.P. Phipps, P.J. Sime, Rochester, NY, p.A2874 10:15 Short-Term Nitrogen Dioxide Exposure Increases Rescue Medication Use in Children with Asthma/L.M. Paulin, E. Matsui, J. Curtin-Brosnan, R. Peng, G. Diette, M.C. McCormack, P. Breysse, D. Williams, N.N. Hansel, Baltimore, MD, p.A2875 10:30 Inhaled Diesel Exhaust Alters Allergen-Induced Bronchial Secretome in Humans/N. Mookherjee, P. Ezzati, V. Spicer, J.A. Hirota, C. Carlsten, Winnepeg, Canada, p.A2876 10:45 Early Life Indoor Inflammatory Exposures and Asthma Risk at Three Years of Age in the Canadian Healthy Infant Longitudinal Development (CHILD) Birth Cohort/T.K. Takaro, Y. Joffres, H. Shu, J. Brook, A.B. Becker, K. McLean, A.J. Wheeler, J.A. Scott, D.L. Lefebvre, H. Sbihi, P.J. Mandhane, P. Subbarao, S.E. Turvey, M.R. Sears, Burnaby, Canada, p.A2877 B16 MINI SYMPOSIUM CYSTIC FIBROSIS (CF) AND NON-CF BRONCHIECTASIS 9:00 a.m. - 11:00 a.m. MOSCONE CENTER Chairing: M.L. Metersky, MD, Farmington, CT A. O’Donnell, MD, Washington, DC Oral Presentations Room 3016/3018 (West Building, Level 3) 9:00 Identifying Modifiable Risk Factors for Rapid Lung Function Decline in Bronchiectasis/T. Fardon, S.M. Finch, M. Crichton, A.J. Dicker, S. Marshall, J.D. Chalmers, Dundee, United Kingdom, p.A2878 9:15 Altered Lung Microbiota Profiles Are Associated with Disease Severity, Exacerbation Frequency and Neutrophilic Inflammation in Bronchiectasis/A.J. Dicker, C. Fong, M. Crichton, A. Cassidy, G. Suarez-Cuartin, O. Sibila, G.G. Einarsson, W. Ibrahim, J.S. Elborn, C.N.A. Palmer, T. Fardon, S. Marshall, J.D. Chalmers, Dundee, United Kingdom, p.A2879 9:30 Neutrophil Elastase Activity During Episodes of Pseudomonas Infection in Early Cystic Fibrosis/L.W. Garratt, A. Kicic, S. Ranganathan, S. Stick, Subiaco, Australia, p.A2880 9:45 SPLUNC1 Dysregulation in the Sputum of Stable Adult Cystic Fibrosis Subjects/C.J. Britto, N. Niu, E. Bruscia, C. Barone, M. Egan, L.E. Cohn, New Haven, CT, p.A2881 10:00 Anti-Pseudomonas Aeruginosa IgG Antibodies and Chronic Airway Infection in Non-Cystic Fibrosis Bronchiectasis/G. Suarez-Cuartin, O. Sibila, A. Smith, H. Abo-Leyah, A. Rodrigo-Troyano, S. Vidal, V. Plaza, T.C. Fardon, J.D. Chalmers, Barcelona, Spain, p.A2882 10:15 Erythromycin Inhibits Expression of P. Aeruginosa Quorum Sensing Genes in the Airways of Non-CF Bronchiectasis Subjects Recruited to the BLESS Randomised Controlled Trial/L.D. Burr, G.B. Rogers, A.C.-H. Chen, S. Taylor, S. Bowler, D. Serisier, M. McGuckin, South Brisbane, Australia, p.A2883 10:30 Gentamicin Induces the Formation and Alters the Composition of Gram Negative Rod Biofilms. This Process is Blocked by Erythromycin Co-Treatment/Y.E. Wang, N. Gonella, R. Devries, D. Witt, S. Prasad, Stanford, CA, p.A2884 10:45 Short-Term and Long-term Effects of Ivacaftor Treatment on Sputum Microbiota in CF Patients with the G551D CFTR Mutation/L. Hoffman, C. Pope, P. Jorth, K.B. Hisert, M. Welsh, P.K. Singh, E.F. McKone, Seattle, WA, p.A2885 ATS 2016 • San Francisco
MONDAY • MAY 16 143 B17 MINI SYMPOSIUM TUBERCULOSIS: SUSCEPTIBILITY AND IMMUNE RESPONSE 9:00 a.m. - 11:00 a.m. MOSCONE CENTER Room 3020/3022 (West Building, Level 3) Chairing: S. Schwander, MD, PhD, Piscataway, NJ P.C. Karakousis, MD, Baltimore, MD H. Koziel, MD, Boston, MA R.N. van Zyl-Smit, MBChB, PhD, Cape Town, South Africa Featured Speaker 9:00 Impact of Smoke on TB Pathogenesis/R.N. van Zyl-Smit, MBChB, PhD, Cape Town, South Africa, Oral Presentations 9:15 Comparison of Bronchoalveolar Lavage (BAL) Cells in Human Subjects and Cynomolgus Macaques Prior to and Following Infection with Mycobacterium Tuberculosis/R.F. Silver, A. Fraser, J.R. Jarvela, T.L. Bonfield, T. Rutledge, J. Flynn, P.L. Ling, Cleveland, OH, p.A2886 9:30 Histone H3K14 Hypoacetylation and H3K27 Hyermethylation Along with HDAC1 Up-Regulation and KDM6B Down-Regulation Are Associated with Active Pulmonary Tuberculosis Disease/Y.-C. Chen, M.-C. Lin, T.-Y. Chao, S.-Y. Leung, C.-C. Wu, W.-F. Fang, Kaohsiung, Taiwan, p.A2887 9:45 Up Regulation of TLR4 Expression in Leukocytes of Co-Infected HIV/TB Patients/E. Mortaz, J. Garssen, M. Marjani, M. Varahram, A.A. Velayati, I.M. Adcock, P. Tabarsi, Utrecht, Netherlands, p.A2888 10:00 Serum Short Chain Fatty Acids Increase the Risk of Tuberculosis in HIV Patients on Antiretroviral Therapy and Inhibit Th1 and Th17 Immune Response/M.D. Weiden, J.C. Clemente, Y. Li, E. Friedman, C. Ruan, J. Cao, A. Pooran, M. Davids, G. Calligaro, R. Dawson, R.N. Van Zyl-Smit, K. Dheda, W.N. Rom, L. Segal, New York, NY, p.A2889 10:15 Cigarette Smoke Impairs Alveolar Macrophage Migration to Mycobacterium Tuberculosis/S.M. O’Leary, S. Levitte, L. Ramakrishnan, M.P. O’Sullivan, J.M. Keane, Dublin, Ireland, p.A2890 10:30 Smokers’ Alveolar Macrophages Demonstrate Impaired Glycolytic Reprogramming in Response to Mycobacterium Tuberculosis Infection/L.E. Gleeson, F.J. Sheedy, D. Triglia, S.M. O’Leary, J.M. Keane, Dublin, Ireland, p.A2891 10:45 Nicotine Impairs Macrophage Control of Mycobacterium Tuberculosis by Binding to Nicotinic Acetylcholine Receptor, Activating Nfkappab and Inhibiting Autophagy/E.D. Chan, J. Stitzel, A. Bai, M. Phillips, X. Bai, Denver, CO, p.A2892 B18 MINI SYMPOSIUM SYMPTOM ASSESSMENT: THE PRACTICAL REALITY 9:00 a.m. - 11:00 a.m. MOSCONE CENTER Room 307 (South Building, Esplanade Level) Chairing: V.M. McDonald, PhD, RN, New Lambton Heights, Australia M. Hodson, MSC, RN, London, United Kingdom Oral Presentations 9:00 Routine Dyspnea Assessment Every Shift: Feasibility and Acceptance of by Nurses/K. Baker, S. Desanto-Madeya, M. Gauthier, M. Mahoney, R. Martinez, R. Banzett, Boston, MA, p.A2893 9:15 Use of Validated Dyspnea Scales Increases Nurses’ Confidence in Their Assessment and Treatment of Dyspnea in Palliative Care Patients/M. Yannacone, V. Carrieri-Kohlman, S. Barbour, San Francisco, CA, p.A2894 9:30 Daily Measure of Quality and Intensity of Dyspnea Throughout Acute Hospitalizations/J.P. Stevens, K. Baker, C.R. O’Donnell, R. Lansing, R. Schwartzstein, R. Banzett, Boston, MA, p.A2895 9:45 Patients with COPD Prioritise Symptoms Experience Differently to Respiratory Nurse Specialists/S. Prigmore, A. Caress, J. Yorke, Manchester, United Kingdom, p.A2896 10:00 Dyspnoea-12 Scores Reported “These Days” Are Greater than Those Reported “Today”: Differences in People with COPD, Asthma and ILD/A.-M. Russell, K.N. Johnston, J. Yorke, M.T. Williams, London, United Kingdom, p.A2897 10:15 Evaluation of Individual Activity Descriptors of the MRC Dyspnoea Scale: Do They Add Up?/J. Yorke, C. Gibons, A. Garrow, S. Tyson, J. Vestbo, D. Singh, N. Khan, P.W. Jones, Manchester, United Kingdom, p.A2898 10:30 A Structural Equation Modeling Analysis of the Relationships Between Symptoms and Physical Performance in Patients with COPD/J. Lee, V.S. Fan, S. Borson, K.C. Pike, M.E. Jarrett, H.Q. Nguyen, Seattle, WA, p.A2899 10:45 Fear of Dyspnea Independently Predicts ER Visits and Self-Management Abilities in COPD Patients/B. Abascal-Bolado, R.P. Benzo, Santander, Spain, p.A2900 B19 MINI SYMPOSIUM BEST OF PEDIATRICS 9:00 a.m. - 11:00 a.m. MOSCONE CENTER Room 3006/3008 (West Building, Level 3) Chairing: M. Rosenfeld, MD, MPH, Seattle, WA A.C. Koumbourlis, MD, MPH, Washington, DC MONDAY MORNING ATS 2016 • San Francisco
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American Thoracic Society Internati
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TABLE OF CONTENTS ATS 2016 INTERNAT
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2 FRIDAY • MAY 13 PG2A CLINICAL P
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4 FRIDAY • MAY 13 Target Audience
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6 FRIDAY • MAY 13 11:15 Case Disc
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8 FRIDAY • MAY 13 Chairing: H.B.
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10 FRIDAY • MAY 13 10:25 Advanced
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12 FRIDAY • MAY 13 Objectives At
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14 SATURDAY • MAY 14 Abdominal Ul
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16 SATURDAY • MAY 14 PG17 BASIC
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18 SATURDAY • MAY 14 1:05 In What
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20 SATURDAY • MAY 14 10:30 Practi
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22 SATURDAY • MAY 14 Objectives A
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24 SATURDAY • MAY 14 10:10 Is My
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26 SUNDAY • MAY 15 Chairing: D.M.
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28 SUNDAY • MAY 15 Chronic Cough:
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30 SUNDAY • MAY 15 • understand
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32 SUNDAY • MAY 15 Target Audienc
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34 SUNDAY • MAY 15 Oral Presentat
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36 SUNDAY • MAY 15 9:15 Hyperpola
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38 SUNDAY • MAY 15 310 A Smartpho
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40 SUNDAY • MAY 15 103 Immunosupp
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42 SUNDAY • MAY 15 A26 POSTER DIS
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44 SUNDAY • MAY 15 822 Incidence
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46 SUNDAY • MAY 15 519 Maternal H
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48 SUNDAY • MAY 15 P14 P15 P16 P1
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50 SUNDAY • MAY 15 P1545 P1546 Fa
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52 SUNDAY • MAY 15 P60 P61 Facili
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54 SUNDAY • MAY 15 P149 P150 Faci
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56 SUNDAY • MAY 15 P749 P750 P751
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58 SUNDAY • MAY 15 Facilitator: P
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60 SUNDAY • MAY 15 P1243 P1244 P1
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62 SUNDAY • MAY 15 P1295 P1296 P1
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64 SUNDAY • MAY 15 P1358 P1359 P1
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66 SUNDAY • MAY 15 P91 Facilitato
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68 SUNDAY • MAY 15 P616 P617 P618
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70 SUNDAY • MAY 15 P914 P915 P916
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72 SUNDAY • MAY 15 P556 P557 P558
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74 SUNDAY • MAY 15 Facilitators:
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76 SUNDAY • MAY 15 P997 P998 P999
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78 SUNDAY • MAY 15 P256 P257 P258
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80 SUNDAY • MAY 15 A61 THEMATIC P
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82 SUNDAY • MAY 15 P824 Facilitat
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84 SUNDAY • MAY 15 P1055 P1056 P1
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86 SUNDAY • MAY 15 P1101 P1102 P1
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88 SUNDAY • MAY 15 P1423 P1424 P1
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90 SUNDAY • MAY 15 P1474 P1475 P1
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192 MONDAY • MAY 16 P1408 Enhance
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194 MONDAY • MAY 16 P1455 P1456 P
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196 MONDAY • MAY 16 P1487 P1488 P
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198 MONDAY • MAY 16 P1514 P1515 P
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200 MONDAY • MAY 16 Facilitator:
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202 MONDAY • MAY 16 P559 P560 P56
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204 MONDAY • MAY 16 WS3 CLINICAL
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206 MONDAY • MAY 16 Satellite ear
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208 MONDAY • MAY 16 Objectives At
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210 MONDAY • MAY 16 encourage tra
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212 MONDAY • MAY 16 B82 BEHAVIORA
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214 MONDAY • MAY 16 B86 BASIC •
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216 MONDAY • MAY 16 and a number
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218 MONDAY • MAY 16 2:30 Mortalit
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220 MONDAY • MAY 16 3:00 Simultan
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222 MONDAY • MAY 16 525 Clinical
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224 MONDAY • MAY 16 320 Sensitivi
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226 MONDAY • MAY 16 113 COPD Subt
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228 MONDAY • MAY 16 1004 Health C
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230 MONDAY • MAY 16 609 Skeletal
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232 MONDAY • MAY 16 5:00 p.m. - 7
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234 TUESDAY • MAY 17 Chairing: D.
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236 TUESDAY • MAY 17 CLINICAL YEA
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238 TUESDAY • MAY 17 This session
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240 TUESDAY • MAY 17 bronchiectas
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242 TUESDAY • MAY 17 Target Audie
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244 TUESDAY • MAY 17 C18 MINI SYM
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246 TUESDAY • MAY 17 415 Investig
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248 TUESDAY • MAY 17 207 Survival
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250 TUESDAY • MAY 17 906 Phenotyp
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252 TUESDAY • MAY 17 807 The Vali
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254 TUESDAY • MAY 17 515 Roles of
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256 TUESDAY • MAY 17 P383 P384 P3
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258 TUESDAY • MAY 17 Facilitator:
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260 TUESDAY • MAY 17 P199 P200 P2
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262 TUESDAY • MAY 17 P620 Facilit
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264 TUESDAY • MAY 17 P428 P429 P4
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266 TUESDAY • MAY 17 P442 P443 P4
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268 TUESDAY • MAY 17 P318 P319 P3
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270 TUESDAY • MAY 17 P474 P475 Fa
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272 TUESDAY • MAY 17 Facilitator:
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274 TUESDAY • MAY 17 P727 P728 P7
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276 TUESDAY • MAY 17 P774 P775 Fa
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278 TUESDAY • MAY 17 C53 THEMATIC
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280 TUESDAY • MAY 17 C55 THEMATIC
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282 TUESDAY • MAY 17 P1095 P1096
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284 TUESDAY • MAY 17 P1167 P1168
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286 TUESDAY • MAY 17 P632 P633 P6
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288 TUESDAY • MAY 17 P546 P547 P5
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290 TUESDAY • MAY 17 Facilitator:
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292 TUESDAY • MAY 17 C65 THEMATIC
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294 TUESDAY • MAY 17 P659 P660 P6
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296 TUESDAY • MAY 17 P1506 P1507
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298 TUESDAY • MAY 17 C70 THEMATIC
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300 TUESDAY • MAY 17 P1363 P1364
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302 TUESDAY • MAY 17 P928 P929 P9
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304 TUESDAY • MAY 17 P973 P974 Fa
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306 TUESDAY • MAY 17 Facilitator:
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308 TUESDAY • MAY 17 C80 THEMATIC
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310 TUESDAY • MAY 17 P98 P99 P100
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312 TUESDAY • MAY 17 • become a
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314 TUESDAY • MAY 17 The topics a
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316 TUESDAY • MAY 17 C85 BASIC
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318 TUESDAY • MAY 17 C89 BASIC
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320 TUESDAY • MAY 17 3:20 Pediatr
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322 TUESDAY • MAY 17 2:45 Long-Te
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324 TUESDAY • MAY 17 918 Sarcoido
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326 TUESDAY • MAY 17 410 Effectiv
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328 TUESDAY • MAY 17 710 Follista
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330 TUESDAY • MAY 17 509 A Mechan
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332 TUESDAY • MAY 17 806 Upper Ai
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334 WEDNESDAY • MAY 18 6:45 Acute
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336 WEDNESDAY • MAY 18 CLINICAL Y
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338 WEDNESDAY • MAY 18 Objectives
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340 WEDNESDAY • MAY 18 D9 BASIC
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342 WEDNESDAY • MAY 18 Oral Prese
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344 WEDNESDAY • MAY 18 10:15 Plas
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346 WEDNESDAY • MAY 18 419 A Nove
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348 WEDNESDAY • MAY 18 216 Simpli
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350 WEDNESDAY • MAY 18 815 Multip
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352 WEDNESDAY • MAY 18 D28 POSTER
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354 WEDNESDAY • MAY 18 720 Repeat
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356 WEDNESDAY • MAY 18 P389 Facil
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358 WEDNESDAY • MAY 18 P439 P440
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360 WEDNESDAY • MAY 18 P10 P11 P1
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362 WEDNESDAY • MAY 18 P52 P53 Fa
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364 WEDNESDAY • MAY 18 P95 P96 P9
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366 WEDNESDAY • MAY 18 P698 P699
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368 WEDNESDAY • MAY 18 D42 THEMAT
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370 WEDNESDAY • MAY 18 P748 Funge
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372 WEDNESDAY • MAY 18 P353 P354
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374 WEDNESDAY • MAY 18 P172 P173
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376 WEDNESDAY • MAY 18 P808 Facil
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378 WEDNESDAY • MAY 18 P526 P527
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380 WEDNESDAY • MAY 18 P579 P580
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382 WEDNESDAY • MAY 18 P944 P945
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384 WEDNESDAY • MAY 18 P991 P992
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386 WEDNESDAY • MAY 18 P1036 P103
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388 WEDNESDAY • MAY 18 P1062 P106
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390 WEDNESDAY • MAY 18 11:45 Intr
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392 WEDNESDAY • MAY 18 12:15 Upda
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394 WEDNESDAY • MAY 18 This sessi
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396 WEDNESDAY • MAY 18 1:30 The B
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398 WEDNESDAY • MAY 18 D88 BEHAVI
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400 WEDNESDAY • MAY 18 3:00 Accel
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402 WEDNESDAY • MAY 18 D96 MINI S
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404 WEDNESDAY • MAY 18 604 CARMA3
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406 WEDNESDAY • MAY 18 702 Potent
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408 WEDNESDAY • MAY 18 803 ICU Ac
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410 WEDNESDAY • MAY 18 Chairing:
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412 WEDNESDAY • MAY 18 404 Interm
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Where today’s science meets tomor