322 TUESDAY • MAY 17 2:45 Long-Term Exposure to Ozone and Accelerated Progression of Percent Emphysema and Decline in Lung Function: The MESA Air and Lung Studies/M. Wang, R.G. Barr, E.A. Hoffman, J. Madrigano, C.P. Aaron, P.D. Sampson, L. Sheppard, S. Vedal, J. Kaufman, Seattle, WA, p.A6163 3:00 Genetic Ancestry is Associated with Baseline Lung Function, CT-Scan Emphysema, and COPD Risk in African Americans and Hispanics from SPIROMICS/V.E. Ortega, E.A. Hoffman, E.J. Ampleford, G.A. Hawkins, R.G. Barr, D.J. Couper, M.K. Han, R. Kanner, E. Kleerup, F.J. Martinez, S.I. Rennard, P.G. Woodruff, D.A. Meyers, E.R. Bleecker, Winston-Salem, NC, p.A6164 3:15 Associations Between Smoking, Telomere Length and Lung Function Decline: Findings from a Population-Based Longitudinal Study/P. Andujar, D. Courbon, E. Bizard, E. Marcos, S. Adnot, P. Demoly, I. Pin, G. Thabut, J. Boczkowski, B. Leynaert, Creteil, France, p.A6165 3:30 Lung Cancer-Specific Mortality Reduction With CT Screening: Outcomes According to Airflow Limitation in the ACRIN NLST Sub-Study (N=18,475)/R.P. Young, F. Duan, E. Greco, R.J. Hopkins, C. Chiles, G.D. Gamble, D. Aberle, Auckland, New Zealand, p.A6166 3:45 Microalbuminuria Predicts the Incidence of Severe Chronic Lower Respiratory Disease Exacerbations in Older Adults: The Multi-Ethnic Study of Atherosclerosis (MESA)-Lung Study/E.C. Oelsner, M.E. Grams, D.R. Jacobs, Jr., R. Kronmal, G.T. O’Connor, D. Rabinowitz, R.P. Tracy, R.G. Barr, New York, NY, p.A6167 4:00 Blood Eosinophils Poorly Correlate with Sputum Eosinophils, and Have Few Associations with Spirometry, Clinical and Quantitated Computed Tomography Measures Compared to Sputum Eosinophils in the SPIROMICS Cohort/A.T. Hastie, N.E. Alexis, C. Doerschuk, N.N. Hansel, S. Christenson, N. Putcha, V.E. Ortega, S.P. Peters, MD, PhD, R.G. Barr, D.J. Couper, E.A. Hoffman, R. Kanner, E. Kleerup, F.J. Martinez, P.G. Woodruff, M.K. Han, D.A. Meyers, J.L. Curtis, E.R. Bleecker, Winston-Salem, NC, p.A6168 C98 MINI SYMPOSIUM AIRWAY REMODELING IN COPD AND ASTHMA 2:15 p.m. - 4:15 p.m. MOSCONE CENTER Room 2016/2018 (West Building, Level 2) Chairing: T. Hackett, PhD, Vancouver, Canada H. Meurs, PhD, Groningen, Netherlands A.L. James, MD, MBBS, PhD, Nedlands, Australia Oral Presentations 2:15 Investigating the Features of Small Airway Obstruction in COPD: Obstructed Small Airways Are an Early Feature of Mild and Moderate Disease/S. Booth, H.-K. Koo, D.M. Vasilescu, L. Mostaco-Guidolin, J.C. Hogg, T.-L. Hackett, Vancouver, Canada, p.A6169 2:30 Brain Derived Neurotrophic Factor Effects on Asthmatic Airway Smooth Muscle: A Profile of Epigenetic Regulation/ L.J. Manlove, G.R. Saint-Croix, M. Freeman, M.A. Thompson, C. Pabelick, Y.S. Prakash, Rochester, MN, p.A6170 2:45 Quantitative Assessment of Airway Remodeling with Birefringence Microscopy: Phenotyping Asthma/M.J. Suter, D.C. Adams, L.P. Hariri, A.J. Miller, J.A. Holz, M.V. Szabari, R.S. Harris, J.L. Cho, J.W. Griffith, D.L. Hamilos, A.D. Luster, B.D. Medoff, Boston, MA, p.A6171 3:00 Heterogeneity of Airway Remodeling Contributes to Airway Hyperresponsiveness in Asthma/C.D. Pascoe, P.D. Pare, G.M. Donovan, Winnipeg, Canada, p.A6172 3:15 Novel Non-Linear Optical Imaging to Understand the Composition of Fibrilar Collagen and Elastin in Remodeled Asthmatic Airways/L.B. Mostaco-Guidolin, E.T. Osei, S. Hajimohammadi, J. Ullah, T.-L. Hackett, Vancouver, Canada, p.A6173 3:30 Mast Cell Tryptase Activates Matrix Metalloproteinase-1 Causing Matrix Remodelling, Airway Smooth Muscle Growth and Airway Obstruction During Asthma Exacerbations/S. Naveed, D.J. Jackson, D. Clements, C. Reynolds, D. Shaw, S.L. Johnston, S.R. Johnson, Nottingham, United Kingdom, p.A6174 3:45 Fibulin-1 Plays Critical Roles in the Pathogenesis of Pulmonary Diseases/P.M. Hansbro, G. Liu, M.A. Cooley, A.G. Jarnicki, A.C.-Y. Hsu, P.M. Nair, T.J. Haw, M. Fricker, S.L. Gellatly, R.Y. Kim, M.D. Inman, G. Tjin, P.A. Wark, J.C. Horvat, B.G. Oliver, W.S. Argraves, D.A. Knight, J.K. Burgess, New Lambton Heights, Australia, p.A6175 4:00 MMP-13 is a Critical Driver of Lung Destruction in a Viral Exacerbation Model of COPD/M.P. Goldklang, F. Cvetkovski, D. Turner, R. Xiao, T. Zelonina, K. Stearns, J. Trischler, P. Sklepkiewicz, P. Elkington, D. Farber, J. D’Armiento, New York, NY, p.A6176 C99 MINI SYMPOSIUM BEYOND THE NATIONAL LUNG SCREENING TRIAL 2:15 p.m. - 4:15 p.m. MOSCONE CENTER Chairing: C.G. Slatore, MD, Portland, OR M.K. Gould, MD, MS, Pasadena, CA Featured Speaker Room 306/308 (South Building, Esplanade Level) 2:15 The Future of Lung Cancer Screening/R.S. Wiener, MD, MPH, Boston, MA, Oral Presentations 2:30 Using Electronic Health Records to Assess Eligibility for Lung Cancer Screening: An Examination of Capture and Reliability of Smoking History Data/L. Sakoda, G. Minowada, G. Mogel, V. Lee, N. Gordon, P. Doria-Rose, L. Kushi, L. Habel, Oakland, CA, p.A6177 2:45 Airflow Limitation and Lung Cancer Risk in a Large Prospective Screening Study (NLST-ACRIN Cohort Analysis, N=18, 714)/R.J. Hopkins, R.P. Young, F. Duan, C. Chiles, E. Greco, G.D. Gamble, D. Aberle, Auckland, New Zealand, p.A6178 ATS 2016 • San Francisco
TUESDAY • MAY 17 323 3:00 Racial and Gender Disparities for Curative Lung Cancer Surgery in the National Lung Screening Trial/A.A. Balekian, Los Angeles, CA, p.A6179 3:15 Estimating the Benefit of CT Screening for Metachronous Lung Cancer/K.L. Hamlington, C.M. Kinsey, J.C. O’Toole, R.D. Stapleton, J.H.T. Bates, Burlington, VT, p.A6180 3:30 Impact of a Bronchial Genomic Classifier on Clinical Decision Making in Patients Undergoing Diagnostic Evaluation for Lung Cancer/J.S. Ferguson, R. Van Wert, Y. Choi, M. Rosenbluth, J. Huang, A. Spira, Madison, WI, p.A6181 3:45 Cost-Effectiveness of the Percepta Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer: An Analytical Framework Based on the AEGIS Studies/D.J. Feller-Kopman, S. Liu, A.M. Garner, M. Decamp, J.B. Pietzsch, Baltimore, MD, p.A6182 4:00 Diagnostic Evaluation of the Indeterminate Pulmonary Nodule Among Military and Veteran Personnel with Suspect Lung Cancer: The DECAMP Consortium/E. Billatos, M. Muse, A. Jiwani, I. Mahon, E. Maple, C.W. Atwood, C. Apgar, J.T. Battaile, R. Browning, E. Garshick, R.H. Goldstein, R.L. Keith, K. More, M. Morris, J.S. Parrish, M. Reid, C. Gatsonis, D. Elashoff, F. Duan, S.M. Dubinett, M. Lenburg, P.P. Massion, D. Remick, I.I. Wistuba, M. Schnall, A. Vachani, A. Spira, Boston, MA, p.A6183 C101 SARCOIDOSIS POSTER DISCUSSION SESSION 2:15 p.m. - 4:15 p.m. MOSCONE CENTER Room 3014 (West Building, Level 3) Poster Viewing 2:15-3:00 Discussion 3:00-4:15 Chairing: M.A. Judson, MD, Albany, NY A.S. Morgenthau, MD, New York, NY E.S. Chen, MD, Baltimore, MD 901 The Foundation for Sarcoidosis Research Sarcoidosis Advanced Registry for Cures/L. Serchuck, G. Spitzer, M. Rossman, R.P. Baughman, D.A. Culver, M. Drent, C. Lipset, B. Stern, Chicago, IL, p.A6184 902 Comparison of Cardiac Magnetic Resonance Imaging and 18F-Fluoro-2-Deoxyglucose Positron Emission Tomography Used for Diagnostic Assessment of Cardiac Involvement in Suspected Cardiac Sarcoidosis Patients/V. Kouranos, R. Sharma, M. Kokosi, J. Baksi, S. Prasad, R. Khattar, K. Wechalekar, A.U. Wells, London, United Kingdom, p.A6185 903 Pulmonary Sarcoidosis Phenotypes: Using Cluster Analysis/M.M. Banoei, N. Sweiss, R.P. Baughman, B.W. Winston, Calgary, Canada, p.A6186 904 The Impact of Age and Left Ventricular Function on Survival in Cardiac Sarcoidosis/Y. Zhou, H. Li, E. Lower, A. Costea, M. Attari, R.P. Baughman, Shanghai, China, p.A6187 905 Clinical Characteristics of Sarcoidosis Patients in America and China/Y. Zhou, H. Li, E. Lower, Shanghai, China, p.A6188 906 A Novel In Vitro Human Model of Sarcoidosis/E.D. Crouser, E. Guirado, M.W. Julian, W. Sadee, A. Papp, A. Friedman, P. White, L. Schlesinger, Columbus, OH, p.A6189 907 Stepwise Approach to Bronchoscopic Diagnosis of Sarcoidosis in Patients with Intrathoracic Adenopathy Employing EBUS, ROSE, and Histology Needles/C. Oberg, T.J. Harkin, New York, NY, p.A6190 908 The Complimentary Role of Transbronchial Cryobiopsy Versus Endobronchial Utrasound (EBUS) for Diagnosing Pulmonary Sarcoidosis/S. Benzaquen, A. Aragaki, T.S. Sripasart, D. Tanase, G. Khana, M. Kirschner, R.P. Baughman, Cincinnati, UT, p.A6191 909 Predicting the Course of Sarcoidosis in the Initial Evaluation/M. Castro, P. Gomes, R.C. Tibana, B. Beraldo, A. Gimenez, C. Fukuda, R. Ferreira, M.R. Soares, C.A. Pereira, Sao Paulo, Brazil, p.A6192 910 The Use of Registry for Sarcoidosis Associated Pulmonary Hypertension (ReSAPH) in the Design of the Riociguat for Sarcoidosis Associated Pulmonary Hypertension (RioSAPH)/R.P. Baughman, S.D. Nathan, P. Engel, J.B. Barney, M.B. Scholand, D.A. Culver, Cincinnati, OH, p.A6193 911 Can the Sarcoidosis Health Questionnaire Predict the Shortand Long-Term Outcomes of Patients with Chronic Sarcoidosis?/K. Tanizawa, T. Handa, S. Nagai, T. Oga, T. Kubo, Y. Ito, K. Aihara, K. Ikezoe, A. Sokai, Y. Nakatsuka, T. Hirai, K. Chin, M. Mishima, T. Izumi, Kyoto, Japan, p.A6194 912 Quality of Life Impairment and Fatigue Are Not Correlated with Mean Pulmonary Artery Pressure in Patients with Sarcoidosis Associated Pulmonary Hypertension/E.M. Carmona, S. Kalra, J.B. Barney, O.A. Shlobin, D.A. Culver, M.B. Scholand, K. Vasilis, E.H. Alhamad, F. Cordova, B. Van Den Blink, R.P. Baughman, Rochester, MN, p.A6195 913 Correlation Between Serum Biomarkers (ACE and Chitotriosidase) and 18F-FDG PET/CT )-Follow Up Study/V. Mihailovic-Vucinic, S. Filipovic-Stepic, J.L. Videnovic Ivanov, M. Stjepanovic, B. Gvozdenovic, Z. Sumarac, Belgrade, Serbia, p.A6196 914 Relation of Neutrophil/Lymphocyte Ratio with Radiological Extent in Pulmonary Sarcoidosis/N. Ocal, D. Dogan, R. Ocal, E. Tozkoparan, O. Deniz, E. Ucar, S. Gumus, C. Tasci, A. Taskin, U. Turhan, Ankara, Turkey, p.A6197 915 The Morphological Feature of Alveolar Macrophage Form on Bronchoalveolar Lavage Fluid in Patients with Sarcoidosis/M. Ishida, H. Ishii, S. Wada, T. Koide, T. Saraya, R. Tazawa, K. Nakata, H. Takizawa, Mikata, Japan, p.A6198 916 Sarcoidosis in Patients with Previous Malignancy/R. Kuint, N. Arish, E. Sapir, L. Levy, A. Abutbul, Z.G. Fridlender, U. Laxer, N. Berkman, Jerusalem, Israel, p.A6199 917 A Novel Method to Quantitate Fluorodeoxyglucose by Positron Emission Tomography (PET) in the Lung Parenchyma of Sarcoidosis Patients/R. Keijsers, N. Sweiss, L.A. Saketkoo, E. Lower, R.P. Baughman, Utrecht, Netherlands, p.A6200 TUESDAY AFTERNOON ATS 2016 • San Francisco
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American Thoracic Society Internati
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TABLE OF CONTENTS ATS 2016 INTERNAT
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2 FRIDAY • MAY 13 PG2A CLINICAL P
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4 FRIDAY • MAY 13 Target Audience
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6 FRIDAY • MAY 13 11:15 Case Disc
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8 FRIDAY • MAY 13 Chairing: H.B.
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10 FRIDAY • MAY 13 10:25 Advanced
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12 FRIDAY • MAY 13 Objectives At
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14 SATURDAY • MAY 14 Abdominal Ul
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16 SATURDAY • MAY 14 PG17 BASIC
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18 SATURDAY • MAY 14 1:05 In What
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20 SATURDAY • MAY 14 10:30 Practi
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22 SATURDAY • MAY 14 Objectives A
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24 SATURDAY • MAY 14 10:10 Is My
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26 SUNDAY • MAY 15 Chairing: D.M.
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28 SUNDAY • MAY 15 Chronic Cough:
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30 SUNDAY • MAY 15 • understand
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32 SUNDAY • MAY 15 Target Audienc
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34 SUNDAY • MAY 15 Oral Presentat
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36 SUNDAY • MAY 15 9:15 Hyperpola
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38 SUNDAY • MAY 15 310 A Smartpho
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40 SUNDAY • MAY 15 103 Immunosupp
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42 SUNDAY • MAY 15 A26 POSTER DIS
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44 SUNDAY • MAY 15 822 Incidence
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46 SUNDAY • MAY 15 519 Maternal H
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106 SUNDAY • MAY 15 L1 U.S. FOOD
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112 SUNDAY • MAY 15 clinician and
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114 SUNDAY • MAY 15 A86 BASIC •
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116 SUNDAY • MAY 15 Chairing: M.J
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118 SUNDAY • MAY 15 3:30 High Pre
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120 SUNDAY • MAY 15 102 Toll-Like
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122 SUNDAY • MAY 15 A103 POSTER D
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124 SUNDAY • MAY 15 719 Lactate R
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126 SUNDAY • MAY 15 1014 Determin
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128 SUNDAY • MAY 15 611 Plasma Mi
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130 SUNDAY • MAY 15 412 Daytime S
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132 SUNDAY • MAY 15 6:30 p.m. - 8
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134 MONDAY • MAY 16 SS111 SS112 S
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136 MONDAY • MAY 16 Target Audien
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138 MONDAY • MAY 16 9:40 Empoweri
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140 MONDAY • MAY 16 9:28 Endotoxi
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142 MONDAY • MAY 16 10:15 Adaptiv
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144 MONDAY • MAY 16 Oral Presenta
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146 MONDAY • MAY 16 624 Neonatal
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148 MONDAY • MAY 16 118 Compariso
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150 MONDAY • MAY 16 912 Should Pa
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152 MONDAY • MAY 16 1015 Resverat
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154 MONDAY • MAY 16 718 Health Re
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158 MONDAY • MAY 16 B35 THEMATIC
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210 MONDAY • MAY 16 encourage tra
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212 MONDAY • MAY 16 B82 BEHAVIORA
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214 MONDAY • MAY 16 B86 BASIC •
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216 MONDAY • MAY 16 and a number
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218 MONDAY • MAY 16 2:30 Mortalit
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220 MONDAY • MAY 16 3:00 Simultan
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222 MONDAY • MAY 16 525 Clinical
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224 MONDAY • MAY 16 320 Sensitivi
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226 MONDAY • MAY 16 113 COPD Subt
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228 MONDAY • MAY 16 1004 Health C
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230 MONDAY • MAY 16 609 Skeletal
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232 MONDAY • MAY 16 5:00 p.m. - 7
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234 TUESDAY • MAY 17 Chairing: D.
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236 TUESDAY • MAY 17 CLINICAL YEA
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238 TUESDAY • MAY 17 This session
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240 TUESDAY • MAY 17 bronchiectas
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242 TUESDAY • MAY 17 Target Audie
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244 TUESDAY • MAY 17 C18 MINI SYM
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246 TUESDAY • MAY 17 415 Investig
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248 TUESDAY • MAY 17 207 Survival
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250 TUESDAY • MAY 17 906 Phenotyp
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252 TUESDAY • MAY 17 807 The Vali
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254 TUESDAY • MAY 17 515 Roles of
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392 WEDNESDAY • MAY 18 12:15 Upda
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394 WEDNESDAY • MAY 18 This sessi
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396 WEDNESDAY • MAY 18 1:30 The B
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398 WEDNESDAY • MAY 18 D88 BEHAVI
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Where today’s science meets tomor