Final Program

198 MONDAY • MAY 16
P1514
P1515
P1516
P1517
P1518
P1519
P1520
P1521
P1522
P1523
Proinflammatory Cytokines and Bronchoalveolar Lavage from
Idiopathic Pulmonary Fibrosis Patients Are Promoting the
Expression of Fibrogenic Factors Through the Stimulation of
Subepithelial Pneumonic Myofibroblasts. A Possible Role for
the Novel Fibrogenic Factor TL1A/c/E. Bouros, E. Filidou, K.
Arvanitidis, D. Mikroulis, P. Steiropoulos, G. Bamias, D. Bouros, G.
Kolios, Alexandroupolis, Greece, p.A4152
Cadmium Induces Vimentin Phosphorylation Through Both
AKT and Cdc2 Signaling in Lung Cells/F.J. Li, H. Li, R. Surolia,
Z. Wang, T. Kulkarni, G. Liu, V.J. Thannickal, V.B. Antony,
Birmingham, AL, p.A4153
Idiopathic Pulmonary Fibrosis Fibroblasts Exhibit
Matrix-Autonomous Upregulation in Non-Muscle Myosin II/
B.D. Southern, L.M. Grove, R.G. Scheraga, S. Abraham, K.A.
Niese, T.T. Egelhoff, M.A. Olman, Cleveland, OH, p.A4154
Evidence of Mesenchymal to Epithelial Transition in Human
Fibroblasts Obtained from Normal Lungs and from Idiopathic
Interstitial Pneumonias/C. Becerril, M. Montano, C. Ramos, J.
Cisneros, C. Mendoza-Milla, M. Checa, A. Pardo, M. Selman,
Mexico City, Mexico, p.A4155
Danaparoid Attenuates Bleomycin-Induced Pulmonary
Fibrosis in Mice/X. Wang, Y. Tanino, T. Nikaido, M. Kikuchi, Y.
Sato, N. Fukuhara, K. Misa, R. Togawa, Y. Suzuki, M. Uematsu, A.
Fukuhara, S. Sato, J. Saito, H. Yokouchi, M. Munakata, Fukushima,
Japan, p.A4156
The Role of p22phox-Dependent NADPH Oxidases in
Bleomycin-Induced Interstitial Lung Disease/B.M. Nagy, C.
Nagaraj, H. Olschewski, A. Olschewski, Graz, Austria, p.A4157
The Role of Bronchiolar Epithelial Cell Migration in Idiopathic
Pulmonary Fibrosis (IPF)/J. Fukumoto, R. Soundararajan, R.F.
Lockey, N. Kolliputi, Tampa, FL, p.A4158
Alveolar Epithelial Cells Release Pro-Fibrotic Mediators in
Response to Endoplasmic Reticulum Stress/K.E. Black, V.A.
Pace, A.M. Tager, Boston, MA, p.A4159
Whole Genome Sequencing Identifies Susceptibility Loci for
DPB/Y. Jin, D. Weng, Shanghai, China, p.A4160
Proteasome-Dependent Degradation of IL-33 in Primary Human
Pulmonary Fibroblasts/A. Clerman, Z. Noor, I.G. Luzina, S.P.
Atamas, Baltimore, MD, p.A4161
P1528
P1529
P1530
P1531
P1532
P1533
P1534
P1535
P1536
P1537
Electrophysiological and Pharmacological Characterization of
Primary K+-, Cl— and Ca2+-Conductances in Human
Pulmonary Fibroblasts/M. Rahman, S. Mukherjee, V. Sheng, L.
Janssen, Hamilton, Canada, p.A4166
Establishment of Non-Infectious Exacerbation Pulmonary
Fibrosis Model in Rat/S. Chen, D. Weng, Shanghai, China,
p.A4167
Identification of Novel Mediators in Lung Fibrosis/J. Verneau,
London, United Kingdom, p.A4168
Melatonin Attenuates TGFß1-Induced Epithelial-Mesenchymal
Transition in Lung Alveolar Epithelial Cells/Y. Na, J. Kang,
Shenyang City, China, p.A4169
Nintedanib Reduces Pulmonary Fibrosis in a Model of
Rheumatoid Arthritis Associated Interstitial Lung Disease/E.F.
Redente, M.A. Aguilar, L.P. Lalire, B.L. Edelman, L. Wollin, D.W.H.
Riches, Denver, CO, p.A4170
Involvement of PARK2-Mediated Mitophagy in Idiopathic
Pulmonary Fibrosis Pathogenesis/K. Kobayashi, J. Araya, H.
Hara, S. Minagawa, M. Yoshida, K. Tsubouchi, T. Kadota, N. Saito,
N. Sato, Y. Kurita, S. Ito, J. Kojima, T. Numata, Y. Kaneko, H.
Asano, M. Yamashita, M. Odaka, T. Morikawa, K. Nakayama, K.
Kuwano, Tokyo, Japan, p.A4171
Functional, Histological and Biochemical Endpoints for
Assessing Antifibrotic Efficacy in a Rat Model of Pulmonary
Fibrosis/H.G. Hoymann, D. Schaudien, T. Hansen, M. Niehof, A.
Braun, Hannover, Germany, p.A4172
Urokinase Plasminogen Activator (uPA) Is Increased in
Interstitial Lung Disease (ILD): A Potential Fibrogenic Mediator
and Biomarker in ILD/M. Schuliga, J. Jaffar, A. Berhan, S.
Langenbach, T. Harris, G. Westall, A.G. Stewart, Parkville,
Australia, p.A4173
Necroptosis Is Involved in Bleomycin Induced Experimental
Lung Injury/Fibrosis/S.W. Park, J.-M. Lee, M.W. Lee, H.J. Seo,
J.-H. Lee, A.S. Jang, D.-J. Kim, S.T. Uh, Y.H. Kim, C.-S. Park,
Bucheon, Korea, Republic of, p.A4174
How Basic Science Methodology Has Changed in the Context
of the Bleomycin Model of Pulmonary Fibrosis/P.S. Kolb, D.
Miller, J. Lee, C. Shimbori, P.-S. Bellaye, K. Ask, M.R.J. Kolb,
Hamilton, Canada, p.A4175
P1524
P1525
Analysis of Lung Injury Models by Using Human MUC1
Transgenic Mice/T. Kubota, M. Sakai, S. Akita, S. Kawase, H.
Ohnishi, A. Yokoyama, Nankoku City, Japan, p.A4162
Rapamycin Insensitive mTOR Signalling Promotes TGF-ß
Induced Pro-Fibrotic Gene Expression in Human Lung
Fibroblasts/H. Woodcock, J. Eley, S. Peace, C. Nanthakumar,
T.M. Maher, P. Mercer, R. Chambers, London, United Kingdom,
p.A4163
P1538
SFTPA1 Mutation in Familial Idiopathic Interstitial Pneumonia
and Lung Cancer/N. Nathan, V. Giraud, C. Picard, H. Nunes, F.
Dastot Le Moal, P. Duquesnoy, B. Copin, M. Reynaud-Gaubert, D.
Valeyre, L.-J. Couderc, T. Chinet, R. Borie, B. Crestani, V. Nau, S.
Tissier, L. Galeron, A. De Ligniville, N. Kuziner, M. Simansour, L.
Mansour Hendili, M. Legendre, C. Kannengiesser, A. Coulomb, L.
Gouya, S. Amselem, A. Clement, Paris, France, p.A7845
P1526
Lung Fibroblasts Derived from Patients with Idiopathic Pulmonary
Fibrosis Are Resistant to Alternaria Alternata-Mediated Cell
Death/J. Im, R.S. Nho, Minneapolis, MN, p.A4164
P1527
The Role of Histone Deacetylase 8 in Fibroblast-Myofibroblast
Differentiation/S. Saito, Y. Zhuang, G. Morris, J. Lasky, New
Orleans, LA, p.A4165
ATS 2016 • San Francisco