Final Program

194 MONDAY • MAY 16
P1455
P1456
P1457
P1458
P1459
P1460
P1461
P1462
P1463
P1464
P1465
P1466
P1467
Support Vector Machine Identifies a Set of Metabolites in Plasma
that Predict Rapid FEV1 Decline in Humans and Mice/ H.
Petersen, J. Sui, S. Plis, Y. Tesfaigzi, Albuquerque, NM, p.A4068
Association of Plasma Levels of sRAGE with 2-Year
Radiographic Emphysema Progression/Y. Zhang, J.M. Bon, J.K.
Leader, D. Chandra, P. An, Y. Chu, D.O. Wilson, C. Fuhrman, F.C.
Sciurba, Pittsburgh, PA, p.A4069
Gender Differences in the Alteration of the Bronchoalveolar
Lavage Cell Proteome in Response to Smoking and COPD/M.
Yang, M. Kohler, H.K. Garberg, J. Grunewald, R. Karimi, F.S.
Berven, M.C. Skold, A.M. Wheelock, Stockholm, Sweden, p.A4070
Endothelial Function and Endothelial-Derived Microparticles
After Exercise in Patients with Chronic Obstructive Pulmonary
Disease/D. Nieri, T. Neri, L. Malagrina, D. Guarino, S. Santerini, S.
Antonelli, C. De Simone, G. De Cusatis, C. Spanu, C. Palombo, B.
Vagaggini, A. Celi, P. Paggiaro, Pisa, Italy, p.A4071
Airway Inflammatory Mediator Determinants of COPD
Exacerbation Severity and Resolution/R.V. Dy, C. Wrona, T.
Murphy, S. Sethi, Buffalo, NY, p.A4072
Genomic Profiling of DNA-Damage Response in Lung Tissue
Identifies Clinical Phenotypes of COPD/M. Sauler, J. Tedrow, J.
Herazo-Maya, F.C. Sciurba, N. Kaminski, P.J. Lee, J.L. Gomez,
New Haven, CT, p.A4073
Age, Sex and Genetic Factors Are Associated with Response
to Ipratropium Among Individuals with Mild COPD in the Lung
Health Study/M. Obeidat, N. Fishbane, N.N. Hansel, N. Rafaels,
R.A. Mathias, I. Ruczinski, T.H. Beaty, K. Barnes, P.D. Pare, D.D.
Sin, Vancouver, Canada, p.A4074
Transcriptomic Alterations Associated with Emphysematous
Lung Destruction in Centrilobular and Panlobular
Emphysema/J.J. Kantrowitz, D. Kinose, D.M. Vasilescu, T.-L.
Hackett, C. Stevenson, J.C. Hogg, M. Lenburg, A. Spira, Boston,
MA, p.A4075
Proteomics of Laser Capture Micro-Dissected Alveolar Tissue
During Lung Development/G. Clair, P. Piehowski, T. Nicola, J.A.
Kitzmiller, N. Ambalavanan, J. Carson, R. Corley, C. Ansong,
Richland, WA, p.A4076
Enhanced Mass Spectrometry-Based Proteomics Can Be Used
to Distinguish Differences in Protein Compositions of Acellular
Emphysematous Versus Normal Lungs/F.E. Uhl, B. Zvarova,
J.G. Fields, B. Deng, Y.W. Lam, D.J. Weiss, D.E. Wagner,
Burlington, VT, p.A4077
Mouse Lung Developmental Gene Expression Profiling Study
Identifies Novel Candidate Genes for Pulmonary Function/K.
Ganguly, L. George, M. Irmler, A. Mitra, T.A. Thimraj, J. Beckers, S.
Upadhyay, H. Schulz, G.D. Leikauf, Chennai, India, p.A4078
The Lung Connectivity Map: Characterizing Lung Specific
Responses to Compound Perturbation/S. Corbett, E. Moses, T.
Wang, J.D. Campbell, C. Perdomo, X. Lu, T. Natoli, R. Narayan, J.
Rosains, A. Subramanian, M.E. Lenberg, A. Spira, Boston, MA,
p.A4079
Proteomic Analysis Reveals Significant Epithelial Remodeling
After In Vitro Exposure to Diacetyl Vapor/M.W. Foster, W.M.
Gwinn, F.L. Kelly, D.M. Brass, J.W. Thompson, M.A. Moseley, D.L.
Morgan, S.M. Palmer, Durham, NC, p.A4080
P1468
P1469
B59
SENP1 and Polycythemia: A Human Experiment in Nature at
High Altitude/P. Azad, G.G. Haddad, La Jolla, CA, p.A7840
Epigenetic Modifications in Peripheral Blood of Human Infants
Born and Raised at High Altitude/S. Krishnan, K. Nephew, M.
Ivan, M.R. Martinez, F. Bonilla, C. Cabana, C.J. Llapur, R.S.
Tepper, Indianapolis, IN, p.A7841
THEMATIC POSTER SESSION
NOVEL GENES AND GENE EFFECTS IN COPD
9:00 a.m. - 4:15 p.m. MOSCONE CENTER
Viewing: Posters will be on display for entire session.
Area H, Hall D (North Building, Lower Level)
Discussion: 11:00-11:45: authors will be present for individual discussion
11:45-12:45: authors will be present for discussion with assigned facilitators
P1006
P1007
P1008
P1009
P1010
P1011
P1012
Association of XRCC5 Polymorphisms with COPD and
COPD-Related Phenotypes in Han Chinese: A Case-Control
Cohort Study/B. Wang, J. Yang, J. Xiao, B. Liang, H. Zhou, X. Ou,
Y. Feng, Chengdu, China, p.A4081
Molecular Characterization of Novel Rare Variants of
SERPINA1 Gene in Alpha-1 Antitrypsin Deficiency Patients
from Spain/B. Martinez-Delgado, N. Matamala, B. Lara, R. Saez,
S. Castillo, M. Molina, A. Texido, D. Retana, T. Fernandez, A.
Otero, L. Lopez, I. Blanco, Madrid, Spain, p.A4082
Linking the COPD Susceptibility Gene Iron-Responsive
Element Binding Protein 2 (IRP2) with Pathological Outcomes
in Experimental COPD/S.M. Cloonan, K. Glass, M.
Laucho-Contreras, A.R. Bhashyam, M. Cervo, M. Pabon, C.
Konrad, F. Polverino, I.I. Siempos, E. Perez, K. Mizumura, M.
Ghosh, H. Parameswaran, N. Williams, K.T. Rooney, Z.-H. Chen,
M.P. Goldklang, G.-C. Yuan, S. Moore, D.L. DeMeo, T.A. Rouault,
J.M. D'Armiento, E. Schon, G. Manfredi, J. Quackenbush, A.
Mahmood, E.K. Silverman, C.A. Owen, A.M.K. Choi, New York
City, NY, p.A4083
Decreased Histone Deacetylase 2 in Peripheral Blood
Monocytes of Patients with Chronic Obstructive Pulmonary
Disease/C. Tan, L. Xuan, S. Cao, G. Yu, H. Qi, H. Wang, Beijing,
China, p.A4084
Role of R213G Polymorphism in Cigarette Smoke-Induced
Acute Lung Injury/R. Gaurav, G.C. Mouradian, B.C. Hartman, J.
Varasteh, C. Fratelli, E. Grayck, R.P. Bowler, Denver, CO, p.A4085
Non-Canonical WNT-5A Compromises Endogenous Lung Repair
in COPD/H.A. Baarsma, W. Skronska-Wasek, K. Mutze, F. Ciolek,
G. John-Schuster, M. Dagouassat, A. Gunther, J. Boczkowski, R.
Smits, A.O. Yildirim, M. Konigshoff, Munich, Germany, p.A4086
Reduced Expression of the Epigenetic Regulator HMGN5
Enhances Susceptibility to Emphysema/T.M. Conlon, L. Merthan,
V. Gailus-Durner, H. Fuchs, M. Hrabe De Angelis, T. Furusawa, M.
Bustin, O. Eickelberg, A.O. Yildirim, Munich, Germany, p.A4087
ATS 2016 • San Francisco