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344 WEDNESDAY • MAY 18<br />

10:15 Plasma Metabolomics Analysis Identifies Candidate<br />

Biomarkers of Flavoring-Induced Bronchiolitis Obliterans/M.W.<br />

Foster, J.W. Thompson, D.M. Brass, M.A. Moseley, D.L. Morgan,<br />

S.M. Palmer, Durham, NC, p.A6452<br />

10:30 Metabolomic Profiling of Childhood Asthma Severity in a<br />

Costa-Rican Population: Insights into Disease<br />

Pathogenesis/R.S. Kelly, A. Dahlin, A.C. Wu, M. McGeachie, D.C.<br />

Croteau-Chonka, S.T. Weiss, J. Lasky-Su, Boston, MA, p.A6453<br />

10:45 Varying Effects of PM2.5, Genetic and Epigenetic Variations in<br />

iNOS Promoter on FeNO in Children/Y. Zhang, M. Salam, K.<br />

Berhane, S. Eckel, E. Rappaport, W. Linn, R. Habre, T. Bastain, F.<br />

Gilliland, Salt Lake City, UT, p.A6454<br />

D18<br />

MINI SYMPOSIUM<br />

CYSTIC FIBROSIS AND PRIMARY CILIARY<br />

DYSKINESIA: TWO SIDES OF THE SAME COIN?<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Chairing: A.J. Shapiro, MD, Montreal, Canada<br />

D. Hayes, MD, Columbus, OH<br />

Oral Presentations<br />

Room 3007/3009 (West Building, Level 3)<br />

9:00 Respiratory Microbiology in Primary Ciliary Dyskinesia:<br />

Comparisons to a Pediatric Cystic Fibrosis Cohort/M.C. Tracy,<br />

J.M. Zirbes, C. Hernandez, D.N. Cornfield, C.E. Milla, Palo Alto,<br />

CA, p.A6455<br />

9:15 Comparison of the Microbiota of the Airway in Children with<br />

Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis/R.J.<br />

Green, S. Vosloo, R. Masekela, S. De Beer, F. Venter, Pretoria,<br />

South Africa, p.A6456<br />

9:30 A Comparison of Anaerobic to Aerobic Power Ratio in Children<br />

with Primary Ciliary Dyskinesia and Healthy Controls/S.<br />

Simsek, D. Inal-Ince, A. Cakmak, E. Calik-Kutukcu, M. Saglam, N.<br />

Vardar-Yagli, N. Emiralioglu, H.U. Ozcelik, H. Sonbahar-Ulu, C.<br />

Bozdemir-Ozel, H. Arikan, N. Kiper, Ankara, Turkey, p.A6457<br />

9:45 In Vivo Cystic Fibrosis (CF) Nasal Epithelial Transcriptomic<br />

Studies Reveal non-CFTR Differential Gene Expression<br />

Associated with CF Lung Disease Severity/D. Polineni, H. Dang,<br />

R.G. Pace, J.R. Stonebraker, X.G. Guo, L.C. Jones, C.R. Esther,<br />

M.P. Boyle, J.F. Chmiel, P.R. Durie, P.J. Gallins, F.A. Wright, W.K.<br />

O’Neal, M. Knowles, Kansas City, KS, p.A6458<br />

10:00 The Influence of Secondhand Smoke Exposure on Arachidonic<br />

Acid Metabolism and Outcomes in Infants and Young Children<br />

with Cystic Fibrosis/B.T. Kopp, L.K. Rogers, A. Mejias, D. Hayes,<br />

Jr., D. Tumin, F. Woodley, R. Thompson, J. Groner, Columbus,<br />

OH, p.A6459<br />

10:15 Minorities with Cystic Fibrosis Are Underrepresented in<br />

Pharmacology Clinical Trials/M.E. McGarry, S.A. McColley, San<br />

Francisco, CA, p.A6460<br />

10:30 Age-Related Survival Disparity Associated with Lung<br />

Transplantation in Cystic Fibrosis: An International Study/<br />

D. Hayes, Jr., A.R. Glanville, D. McGiffin, J.D. Tobias, D. Tumin,<br />

Columbus, OH, p.A6461<br />

Featured Speaker<br />

10:45 Contrasting the CF and PCD Phenotypes/S.D. Davis, MD,<br />

Indianapolis, IN,<br />

D19<br />

MINI SYMPOSIUM<br />

CLINICAL STUDIES IN PH<br />

9:00 a.m. - 11:00 a.m. MOSCONE CENTER<br />

Chairing: R.T. Zamanian, MD, Stanford, CA<br />

R. Souza, MD, PhD, Sao Paulo, Brazil<br />

I. Lang, MD, Vienna, Austria<br />

Oral Presentations<br />

Room 3010/3012 (West Building, Level 3)<br />

9:00 Comprehensive Characterization of Insulin Resistance and Its<br />

Association with Ventricular Function in Pulmonary Arterial<br />

Hypertension/R.E. Wells, M. Cuttica, R. Dash, F. Abbasi, M. Van<br />

De Veerdonk, I.R. Preston, A.R. Hemnes, A.J. Sweatt, M.<br />

Gomberg-Maitland, R.T. Zamanian, Stanford, CA, p.A6462<br />

9:15 Sarcoidosis-Associated Pulmonary Hypertension in the Modern<br />

PAH-Targeted Therapy Era: Experience from the French<br />

Registry/A. Boucly, H. Nunes, X. Jais, V. Cottin, A. Tazi, O. Sanchez,<br />

G. Prevot, M. Reynaud Gaubert, C. Dromer, C. Viacroze, D. Horeau<br />

Langlard, C. Pison, E. Bergot, D. Montani, G. Simonneau, M. Humbert,<br />

O. Sitbon, L. Savale, Le Kremlin Bicêtre, France, p.A6463<br />

9:30 Serial Vasoreactivity Reassessment Is a Prognostic Tool in<br />

Pulmonary Arterial Hypertension/A.J. Sweatt, E.F.<br />

Spiekerkoetter, A. Hsi, Y. Sung, V. De Jesus Perez, K. Kudelko,<br />

R.T. Zamanian, Stanford, CA, p.A6464<br />

9:45 Extended Evaluation of emPHasis-10 Quality of Life<br />

Questionnaire in PH/I. Smith, C. Billings, D. Kiely, J. Yorke, I.<br />

Armstrong, Sheffield, United Kingdom, p.A6465<br />

10:00 Targeting the Prostacyclin Pathway in the Treatment of<br />

Connective Tissue Disease Associated Pulmonary Arterial<br />

Hypertension (PAH): Insights from the Randomized Controlled<br />

GRIPHON Trial with Selexipag/S.P. Gaine, R.N. Channick, L. Di<br />

Scala, N. Galie, H.-A. Ghofrani, M.M. Hoeper, I. Lang, V.<br />

McLaughlin, R. Preiss, L.J. Rubin, G. Simonneau, O. Sitbon, V.<br />

Tapson, K.M. Chin, Dublin, Ireland, p.A6466<br />

10:15 Comparative Effectiveness of Pharmacological Interventions for<br />

Pulmonary Arterial Hypertension: A Systematic Review and<br />

Network Meta-Analysis/S. Jain, R. Khera, Z. Wang, M.H. Murad, A.<br />

Blevins, G.A. Schmidt, S. Singh, A.K. Gerke, Iowa City, IA, p.A6467<br />

10:30 A Randomized Open Label Study Comparing First-Line<br />

Treatment with Bosentan or Sildenafil in Chronic<br />

Thromboembolic Pulmonary Hypertension/E. Gotti, M. Palazzini,<br />

A. Manes, C. Bachetti, G. Mazzanti, A. Rinaldi, F. Dardi, A. Albini, E.<br />

Monti, S. Fukui, D. Guarino, N. Galie, Bologna, Italy, p.A6468<br />

ATS 2016 • San Francisco

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