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412 WEDNESDAY • MAY 18<br />

404 Intermittent Hypoxia Augments Mesangial Matrix Expansion by<br />

Increasing Glomerular Expression of TGF-b and CTGF<br />

Proteins/B.H. Abuyassin, M. Badran, N. Ayas, I. Laher, Vancouver,<br />

Canada, p.A7725<br />

405 nmMLCK: A Key Player in Intermittent Hypoxia-Induced<br />

Inflammatory Vascular Remodeling?/C. Arnaud, S. Recoquillon,<br />

S. Bouyon, E. Lemarie, S. Cachot, M. Toral, C. Martinez, R.<br />

Andriantsitohaina, J.L. Pepin, Grenoble, France, p.A7726<br />

406 Circulating Plasma Exosomes and CardioMetabolic Function<br />

in Mice Exposed to Long-Term Alternating Dark-Light Cycles<br />

Mimicking Shift Work/A. Khalyfa, Z. Qiao, V. Poroyko, A.<br />

Gileles-Hillel, A.A. Khalyfa, M. Akbarpour, D. Gozal, Chicago, IL,<br />

p.A7727<br />

407 Activation of Integrated Stress Response (ISR) and<br />

Intermittent Hypoxia (IH)-Induced Metabolic Dysfunction in a<br />

Mouse Model of Sleep Apnea/A. Khalyfa, Z. Qiao, A.<br />

Gileles-Hillel, A.A. Khalyfa, M. Akbarpour, B. Popko, B, D. Gozal,<br />

Chicago, IL, p.A7728<br />

408 Activation of Integrated Stress Response (ISR) By Sleep<br />

Fragmentation During Late Gestation (LG-SF) in Mouse Is<br />

Critical to Emergence of Metabolic Phenotype in Adult<br />

Offspring/A. Khalyfa, Z. Qiao, A.A. Khalyfa, A. Gileles-Hillel, M.<br />

Akbarpour, B. Poroyko, D. Gozal, Chicago, IL, p.A7729<br />

409 Endoplasmic Reticulum Stress as a Novel Inducer of Hypoxia<br />

Inducible Factor-1 Activity: Its Role in the Susceptibility to<br />

Myocardial Ischemia-Reperfusion Induced by Chronic<br />

Intermittent Hypoxia/E. Belaidi, A. Thomas, G. Bourdier, S.<br />

Moulin, E. Lemarie, R. Tamisier, P. Levy, J.L. Pepin, I. Korichneva,<br />

D. Godin-Ribuot, C. Arnaud, Grenoble, France, p.A7730<br />

410 High-Intensity Training Reduces Intermittent Hypoxia-Induced<br />

ER Stress and Myocardial Infarct Size/G. Bourdier, P. Flore, H.<br />

Sanchez, J.L. Pepin, E. Belaidi, C. Arnaud, Grenoble, France,<br />

p.A7731<br />

411 NF-kB Pathway Plays a Critical Role in Intermittent Hypoxia<br />

Induced Macrophage Foam Cell Formation/T. Imamura, G.G.<br />

Haddad, La Jolla, CA, p.A7732<br />

412 Endothelial Dysfunction in Diabetic Mice Is Exacerbated by<br />

Chronic Intermittent Hypoxia (CIH)/M. Badran, N. Ayas, I. Laher,<br />

Vancouver, Canada, p.A7733<br />

413 Low Frequency Intermittent Hypoxia Reduces<br />

Endothelium-Dependent Contraction in C57 Mice with<br />

Diet-Induced Obesity/M.Y.K. Lee, J.C.W. Mak, M.S.M. Ip, Hong<br />

Kong, Hong Kong Prc, p.A7734<br />

414 Hepatocyte Knockout of HIF-1a Accentuates Metabolic<br />

Improvement in Sustained Hypoxia/O. Mesarwi, M.-K. Shin, S.<br />

Bevans-Fonti, C.P. O’Donnell, V.Y. Polotsky, Baltimore, MD,<br />

p.A7735<br />

415 Various Degrees of Intensities of Intermittent Hypoxia on<br />

Adipogenesis in Diet-Induced Obese Mouse Model/Y. Wang,<br />

M.Y.K. Lee, J.C.W. Mak, M.S.M. Ip, Hong Kong, Hong Kong Prc,<br />

p.A7736<br />

416 Late Gestational Intermittent Hypoxia Leads to Metabolic and<br />

Epigenomic Alterations in Adult Offspring/R. Cortese, A.<br />

Khalyfa, R. Bao, J. Andrade, D. Gozal, Chicago, IL, p.A7737<br />

417 Role of COX-2 in Intermittent Hypoxia-Induced Tumor Growth<br />

in a Murine Model of Obstructive Sleep Apnea/I. Almendros, N.<br />

Campillo, M. Torres, D. Gozal, J.M. Montserrat, C. Picado, R.<br />

Farre, D. Navajas, Barcelona, Spain, p.A7738<br />

418 Intermitent Hypoxia Increases Tumor Angiogenesis in a<br />

Mouse Model of Heterotropic Kidney Cancer/M. Torres, A.<br />

Vilaseca, N. Campillo, M. Musquera, J.M. Montserrat, A. Alcaraz,<br />

R. Farre, I. Almendros, Barcelona, Spain, p.A7739<br />

419 Progression of Tumor Growth in Intermittent Hypoxia is<br />

Associated with Decreased Number of Granzyme B Expressing<br />

CD8+ T Cell Lymphocytes/M. Akbarpour, A. Khalyfa, Q.<br />

Zhuanhong, A.A. Khalyfa, A. Gileles-Hillel, I. Almendros, R. Farre,<br />

D. Gozal, Chicago, IL, p.A7740<br />

420 Antioxidant Tempol Ameliorates Intermittent Hypoxia-Induced<br />

Melanoma Lung Metastasis in a Mouse Model of OSA/L. Li, M.<br />

Liang, Y. Fang, J. Cao, B. Chen, Tianjin, China, p.A7741<br />

421 A Membrane Progesterone Receptor Agonist Reduces Apnea<br />

Frequency in Newborn Male and Female Rats/N. Uppari, H.<br />

Kouchi, V. Joseph, A. Bairam, Quebec, Canada, p.A7742<br />

422 Severe Chronic Intermittent Hypoxia Could Mask the Severity<br />

of Lung Cancer, in Terms of Plasmatic Tumor Markers/T.<br />

Gallego-Martin, E. Gonzalez-Obeso, E. Olea, S. Yubero, I. Docio,<br />

A. Obeso, Valladolid, Spain, p.A7743<br />

D110<br />

POSTER DISCUSSION SESSION<br />

UNUSUAL TUMORS OF THE CHEST<br />

1:30 p.m. - 3:30 p.m. MOSCONE CENTER<br />

Room 309 (South Building, Esplanade Level)<br />

Poster Viewing 1:30-2:15<br />

Discussion 2:15-3:30<br />

Chairing: D.E. Ost, MD, MPH, Houston, TX<br />

L.T. Tanoue, MD, New Haven, CT<br />

301 Atypical Multifocal Pulmonary Carcinoid Tumor: A Case<br />

Report of a Very Rare Neoplasm/C.A. Celis Preciado, P. Gil, C.<br />

Zuluaga, L. Jaramillo, Bogota, Colombia, p.A7744<br />

302 Bilateral Synchronous Pulmonary Carcinoid Tumors Treated<br />

with Staged Segmentectomy/A. Attili, J. Shaw, Brooklyn, NY,<br />

p.A7745<br />

303 Atypical Large Hydropneumothorax in the Setting of an<br />

Uncommon Lung Neuroendocrine Tumor/J.M. Sosa, L.<br />

Carrasco, F. Hafeez, M. Abdullahi, R. Ayinla, New York, NY,<br />

p.A7746<br />

304 A Rare Case of Mucoepidermoid Carcinoma of the Lung/A.<br />

Rajagopal, A.P. Maskey, Lexington, KY, p.A7747<br />

305 Endobronchial Leiomyoma Presenting with Asthma-Like<br />

Symptoms: Successfully Treated by Sleeve Resection/R.<br />

Hurezeanu, A. Kaell, L. Cardinal, Port Jefferson, NY, p.A7748<br />

ATS 2016 • San Francisco

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