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BOOKS OF RtfiDIfGS - PAHO/WHO

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- 370 -<br />

Application of Cost-Benefit Analysis to Health Setvices /<br />

in which people are so classified. From other studies it would appear that a host f(<br />

factor such as health insurance, earnings as an expression of the value of time, ae, arad<br />

the supply of providers, ae important determinants of the demand for physici a<br />

ei ices (1 2).<br />

The assertion that the supply of services for sick care is inelastic is not unique to<br />

Garfield. In the area of trends in the education of physicians, which ltakes longr and<br />

therefore responds more slowly than any other health occupation, my own readin<br />

indicates that even this system has been somewhat responsive, even while insiting that<br />

clas size in medical school must be kept small (18, p. 101), and still moro responsive<br />

after the policy decision to expand enrollment was made and implemented by funding.<br />

Whether the supply response has been sufficient to meet rising demand is, of course, a<br />

different issue.<br />

The most serious reservation I have about Garfield's position touches closely on the<br />

nature and function of cost-benefit analysis. If complete prepayment serves to create a<br />

condition of perpetual excessive demand, then some rationing or control measures are<br />

dearly indicated. Why assume, without c¿mparing alternatives, that automated<br />

multiphasic screening is the most appropriate instrumentality? It seems to me that wher<br />

the stated purposes of a program change, so should the menu of alternatives to be<br />

considered.<br />

Two reports by Collen (101, 102) on the cost of screening fil a real need. Two<br />

measures are presented-cost per test and cost per screening. Cost per test reflects only<br />

direct departmental costs, whde cost per screening incorporates an allocation of overhead<br />

expense. The article published in 1970 (102) offers a costing rule: in order to allow for all<br />

costs incurred, double the reported cost per test. The earlier article (101), which appears<br />

to present essentially the same data, suggests a blow-up of 50 per cent; I am unable to<br />

account for the difference.<br />

Since the screening process is automatic, the capital equipment is indivisible, and all<br />

procedures are schedulable, economies of scale are to be expected. The larger the scale of<br />

operation, the lower is the average unit cost. However, to achieve the lower cost, full<br />

utilization of existing facilities is essential. Accordingly, it is said to be advantageous to<br />

have available a source of stand-by patients, such as those awaiting admission to the<br />

hospital (103).<br />

Collen's second article (102) goes beyond cost per test or per screening, and reports<br />

cost per positive case. For manmmography a prevalence rate of 1.2 per cent converts the<br />

unit cost of S4.90 into a cost per positive case of $408. Since one-fifth of the women<br />

with positive mammograms have cancer of the breast, the screening cost per true positive<br />

case is 52,000. His doubling rule would raise the cost to S4,000. The cost of diagnosis for<br />

all five women and of treatment for one is still excluded.<br />

The proportion of false positives is a function not only of the accuracy of the<br />

screening test but also of the prevalence rate (113, 114). There are two reasons for aiming<br />

to keep down the number of false positives: to avoid neediess anxiety, and to prevent<br />

iatrogenic disease associated with the diagnostic process itself.<br />

The data reported to date from the Kaiser-Permanente laboratories indicate that<br />

automated multiphasic screening is both feasible and affordable. The quaetion is whether<br />

it if; worthwhile. One answer is in terms of its effects on health. The Advisory Committee<br />

on Automated Multiphasic Health Testing and Services (AMHTS) (1 15) states that much<br />

of disease uncovered by testing will be chronic or not reversible; it will not yield a saving

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