Medycyna Wieku Rozwojowego

Tissue markers of Epstein-Barr virus (EBV) infection in B-cell non-Hodgkin’s lymphomas
Fig. 3. Electrophoresis in 2% agarose of PCR-amplified EBV-DNA fragment of 480 bp length
(EBNA1) from the tumour of B-cell NHLs and controls
Legend:
KBL – kilo base label
1 – pUC 19 DNA/Msp I (Hpa II) size marker (KBL)
2 – PCR-amplified product of EBV-DNA (EBNA1)
(480 bp) using oligonucleotide primers EB1 and
EB2 in positive control material
3 – EBV-negative lymphoma; no product in PCR
reaction
Correlations between studied cellular markers of EBV in patients with B-cell NHLs
and non-neoplastic material and histological diagnosis
In children with B-cell NHLs, positive correlation was demonstrated between
expression of EBNA2 and LMP1, EBNA2 and EBER as well as between LMP1 and
EBERs (Spearman correlation coefficient of 0.627; 0.489; 0.512, respectively, p