Sažeci 2. Hrvatskog kongresa medicinske biokemije - Klinički zavod ...

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Sažeci 2. Hrvatskog kongresa medicinske biokemije
Rezultati dosadašnje procjene troponina T pokazali su da troponinT:
1. ima visoku osjetljivost i specifičnost poglavito u bolesnika s
pridruženom ozljedom skeletne muskulature,
2. pruža dijagnostičku vrijednost jednaku onoj koja se dobije
mjerenjem CK-MB u bolesnika u ranoj fazi srčanog infarkta (unutar
prva 24 sata) odnosno veću dijagnostičku vrijednost od vrijednosti CK-
MB u bolesnika koji su u bolnicu došli 48 i više sati nakon infarkta,
3. omogućuje dijagnozu srčanog infarkta i nakon 1-2 tjedna od
početka bolova,
4. omogućuje procjenu rizika za nastanak infarkta u bolesnika s
nestabilnom anginom pektoris,
5. neinvazivan je pokazatelj uspjeha trombolitičke terapije i
6. omogućuje procjenu nastanka srčanog infarkta tijekom i nakon
učinjenog operativnog zahvata aortokoronarnog premoštenja.
R3/1
LIPID DISORDERS: APO Al/B AND LP(a), SIMPLE
ROUTINE METHODS FOR THE MEASUREMENT OF
IMPORTANT RISK FACTORS
G. Giinther
Apolipoprotein(s) Al and B have been known for a long time as
important factors for the establishment of an individual's atherosclerotic
risk. Simple routine methods based on turbidimetric measurements
which can be used on routine photometric analvsers, are presented
and the performance data are discussed.
Lp(a) in contrast to Apo Al and Apo B has for quite awhile been
evaluated with respect to its value for atherosclerotic risk assessment.
Only a few years ago these studies showed quite clearlv that Lp(a) is
an independent risk factor for development of atherosclerotic lesions.
Structure and function of Lp(a) are shown and the correlation between
genetic variations and the assay response is discussed. The turbidimetric
routine method is presented and it is proved that this
methodologv, though simple is able to produce reliable results.
BIOCHEMIA MEDICA god. 6, br. 1, 1996 83