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SLEEP 2011 Abstract Supplement

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B. Clinical Sleep Science VI. Sleep Disorders – Hypersomnia<br />

0608<br />

DRIVING AND <strong>SLEEP</strong> DISORDERS: DOES MSLT OR MWT<br />

BETTER PREDICT DRIVING PERFORMANCE?<br />

Philip P, Capelli A, Sagaspe P, Raimondi M, Taillard J<br />

USR3413 CNRS, Bordeaux, France<br />

Introduction: The maintenance of wakefulness test (MWT) predicts<br />

simulated and real driving performance in non treated Obstructive Sleep<br />

Apnea Syndrome (OSAS) patients. Recently, epidemiological studies<br />

reported higher risk of road accidents for narcolepsy and hypersomnia<br />

comparing to OSAS. The aim of our study is to determine the ability of<br />

objective sleepiness measures (MWT or MSLT) to predict driving performance<br />

in patients suffering from OSAS and hypersomnia compared<br />

to healthy controls.<br />

Methods: 148 subjects (38 healthy controls, 42 narcolepsy-hypersomnia<br />

and 70 OSAS patients) performed a total of 96 MWT (4X40-minute<br />

trials) and 77 MSLT (5x20-minute trials). For each test, a 40 min driving<br />

session on real car driving simulator with monotonous driving scenario<br />

was performed. Participants were divided into 3 groups defined by their<br />

scores at MWT or MSLT (pathological (0-19 min for MWT and 0-8 min<br />

for MSLT), intermediate (20-33 min for MWT and 9-11 min for MSLT),<br />

and alert (34-40 min for MWT and 12-20 min for MSLT).<br />

Results: The results showed that only sleep latencies at MWT were correlated<br />

with number of inappropriate line crossings (r =- 0.31, p

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