SLEEP 2011 Abstract Supplement
SLEEP 2011 Abstract Supplement
SLEEP 2011 Abstract Supplement
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B. Clinical Sleep Science XII. Sleep and Aging<br />
0889<br />
PREVALENCE AND CORRELATES FOR <strong>SLEEP</strong><br />
COMPLAINTS IN OLDER ADULTS IN LOW AND MIDDLE<br />
INCOME COUNTRIES: A 10/66 DEMENTIA RESEARCH<br />
GROUP STUDY<br />
Mazzotti DR 1 , Guindalini C 1 , Sosa AL 2 , Ferri CP 2 , Tufik S 1<br />
1<br />
Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil,<br />
2<br />
Institute of Psychiatry, King’s College London, London, United<br />
Kingdom<br />
Introduction: Although it is well recognized that the prevalence of<br />
sleep complaints increases in older ages, estimations of this parameter<br />
in developing countries are still unknown. The present study aims to describe<br />
the prevalence and estimate prevalence ratios of sleep complaints’<br />
correlates in a large population of older adults from low and middle income<br />
countries (LAMIC).<br />
Methods: A cross-sectional survey was performed in 16,680 65 yearold<br />
or older residents in catchment areas of eight LAMIC (Cuba, Dominican<br />
Republic, Peru, Venezuela, Mexico, China, India and Puerto<br />
Rico) as part of the 10/66 Dementia Research Group research program.<br />
Information about socio-demographic factors, lifestyle and health status<br />
as well as questions regarding sleep complaints was obtained. The<br />
prevalence of sleep complaints was estimated based on the question:<br />
“Have you had trouble sleeping recently?”. The results (with robust 95%<br />
confidence intervals) were standardized by age group, sex, household<br />
clustering and residence site (urban or rural), for each studied country.<br />
Prevalence ratios were derived from Poisson regression models for each<br />
country and fixed or random effects meta-analyses was used to combine<br />
them.<br />
Results: Standardized prevalence of sleep complaints varied from 9.1%<br />
(China) to 37.7% (India). Overall, after correction for all other variables,<br />
the meta-analysis showed that female gender, urban residence, low educational<br />
level, low physical activity status, high scores in pain score,<br />
poor health condition, higher memory impairment score, presence of<br />
DSMIV major depression, mild cognitive impairment and high number<br />
of co-morbidities were associated with the presence of sleep complaints<br />
(p10: OR 1.98, 95% CI 1.35, 2.92) In<br />
age-adjusted models, the presence of RLS was associated with a higher<br />
likelihood of nighttime wakefulness >1.5 hours (OR 1.65, 95% CI 1.13,<br />
2.40) and frequent awakenings (>8 episodes) of 5 min or more (OR 1.53,<br />
95% CI 1.04, 2.25). In multivariable models, these associations were attenuated<br />
and were of borderline significance.<br />
Conclusion: RLS is common in very elderly women and is associated<br />
with increased subjective sleep complaints and, to a lesser degree, with<br />
increased objectively measured sleep fragmentation.<br />
Support (If Any): The Study of Osteoporotic Fractures (SOF) is supported<br />
by National Institutes of Health funding. The National Institute<br />
on Aging (NIA) provides support under the following grant numbers:<br />
AG05407, AR35582, AG05394, AR35584, AR35583, R01 AG005407,<br />
R01 AG027576-22, 2 R01 AG005394-22A1, and 2 R01 AG027574-<br />
22A1, AG05407, AR35582, AG05394, AR35584, AR35583, AG026720.<br />
0891<br />
PREDICTORS OF BRIGHT LIGHT EXPOSURE IN OLDER<br />
POST-ACUTE REHABILITATION PATIENTS<br />
Fung CH 1 , Martin JL 2,3 , Josephson KR 2 , Jouldjian S 2 , Alessi CA 2,3<br />
1<br />
Cedars-Sinai Sleep Medicine Fellowship Program, Cedars-Sinai<br />
Medical Center, Los Angeles, CA, USA, 2 Geriatric Research,<br />
Education and Clinical Center (GRECC), VA Greater Los Angeles<br />
Healthcare, North Hills, CA, USA, 3 David Geffen School of Medicine<br />
at UCLA, Los Angeles, CA, USA<br />
Introduction: Fragmented sleep is common among older patients undergoing<br />
inpatient post-acute rehabilitation (PAR). Prior research has<br />
demonstrated that most institutionalized older adults are never exposed<br />
to bright light (> 1,000 lux), and that bright light therapy consolidates<br />
sleep and improves rest/activity rhythms. We aimed to describe levels<br />
and predictors of bright light exposure in the PAR setting.<br />
Methods: We examined light data from wrist actigraphs for 1 week<br />
by 262 PAR patients (aged > 65 years) at 1 community and 1 Veterans<br />
Administration (VA) site. We assessed bivariate relationships between<br />
bright light exposure and frequency of naps, as well as minutes<br />
of daytime sleep. Using logistic regression, we modeled the relationship<br />
between bright light exposure (mean daily minutes > 1000 vs. < 1000<br />
lux) and demographics (gender, age, race, marital status), rehabilitation<br />
factors (bed near window, reason for admission, facility, admission functional<br />
status, Cumulative Illness Rating Scale-Geriatrics, Geriatric Depression<br />
Scale, Geriatric Pain Measure, Mini-Mental Status Exam, and<br />
Lubben Social Network Scale.<br />
Results: Twenty-six percent of patients had no bright light exposure.<br />
On average, patients were exposed to 15.7 (SD 24.6) minutes of light<br />
> 1000 lux/day and were exposed to no light > 1000 lux on 52.8% (SD<br />
36.1) of recorded days. The average maximum duration of bright light<br />
exposure on any one day was 44.4 minutes (SD 57.6). In regression<br />
analyses predicting bright light exposure, there was no association with<br />
daytime sleep (P>.05) or other measured variables. Patients at the VA<br />
site were exposed to less bright light (adjusted OR= 0.23, p