SLEEP 2011 Abstract Supplement

B. Clinical Sleep Science XIII. Sleep and Gender
(for all cases, t = 12.3 years because of violation of the proportional hazards assumption.
Results: Insomnia with short sleep duration was associated with increased
cardiovascular mortality (adjusted HR: 1.38 (95% CI 1.18,
1.63)) within 12.3 years of follow-up. However, this association was
similar in magnitude to that of sleep duration < 6 hours alone (1.37(1.09,
1.73)). Baseline diabetes increased the risk for cardiovascular disease
associated with insomnia with short sleep duration. The association between
insomnia with short sleep duration did not vary by incident hypertension
or diabetes status. Insomnia with short sleep duration was
not related to cardiovascular mortality beyond 12.3 years of follow-up.
Conclusion: Short sleep duration may drive the relationship between
insomnia with short sleep duration and increased cardiovascular mortality
in women.
Support (If Any): Dr. Tom, a UTMB BIRCWH Scholar, is supported
by a research career development award (K12HD052023, PI: Berenson),
that is co-funded by the Eunice Kennedy Shriver National Institute
of Child Health & Human Development (NICHD), the Office of
Research on Women’s Health, and the National Institute of Allergy &
Infectious Diseases (NIAID). The content is solely the responsibility of
the authors and does not necessarily represent the official views of the
Eunice Kennedy Shriver National Institute of Child Health & Human
Development or the National Institutes of Health. This project was also
supported by the National Institute on Aging (T32 AG027677).
0901
PREVALENCE OF ALVEOLAR HYPOVENTILATION IN
MENOPAUSAL WOMEN PRESENTING FOR EVALUATION
OF A SLEEP COMPLAINT
Bogan R 1,2 , Turner J 1
1
SleepMed of SC, SleepMed, Columbia, SC, USA, 2 School of
Medicine, University of SC, Columbia, SC, USA
Introduction: In a group of menopausal women ages 40-65 presenting
for sleep evaluation with PSG, an effort is made to examine prevalence
of alveolar hypoventilation syndrome (AH) and review demographics
as well as sleepiness. Epworth Sleepiness Scale (ESS) is a validated tool
measuring excessive daytime sleepiness (EDS).
Methods: Records of 21362 women undergoing baseline PSGs from
2009-2010 at SleepMed were reviewed. ESS was administered prior to
each study. Oxygen desaturation index (ODI) was measured at equal to
or greater than the 4% level during the total sleep time as well as saturation
index time less than 90%. Patients were selected with low RDI but
sustained desaturation. Comparison was made with patients RDI >15
without regard to ODI.
Results: Of 21362 women that were studied, 12063 (56%) women
were 40-65. Of the 12063 women, 5447(45%) were identified to have
sleep disordered breathing (AH+OSA=SDB). AH group accounted for
686/12063 (6%) of the total and 686/5447 SDB (13%) of women ages
40-65. AH was characterized by RDI< 10, nadir oxygen less than 85%,
time below 90% > 10 minutes, ODI