SLEEP 2011 Abstract Supplement

B. Clinical Sleep Science XIII. Sleep and Gender
Conclusion: Most salaried men and housewives have sleep disorders including
OSAS, PLMS, and PPI. Although OSAS is major sleep problem
in all salaried men and housewives, PLMS is more in housewives and
PPI is more in salaried men.
0911
THE RELATIONSHIP BETWEEN RESTLESS LEGS
SYNDROME AND HYPERTENSION IN MIDDLE-AGED
WOMEN
Batool-Anwar S 1,2 , Malhotra A 1 , Forman J 1,2 , Winkelman J 1 , Li Y 2,3 ,
Gao X 2,3
1
Sleep Medicine, Brigham and Women’s Hospital, Boston, MA, USA,
2
Channing Laboratory, Brigham and Women’s Hospital, Boston, MA,
USA, 3 Department of Nutrition and Epidemiology, Harvard School of
Public Health, Boston, MA, USA
Introduction: Limited research suggests a relationship between Restless
Legs Syndrome (RLS) and hypertension but no direct association
has been established. We, therefore, assessed the relationship between
RLS and hypertension among middle-aged women.
Methods: This is a cross-sectional observational study including 65,544
women (aged 41-58 years) participating in Nurses Health Study II. The
participants with diabetes and arthritis were excluded as these conditions
can mimic RLS. RLS was assessed by a self-administered questionnaire
based on the International Restless Legs Study Group criteria. Information
on diagnosis of hypertension and blood pressure values were collected
via questionnaires. Multivariable logistic regression models were
used to analyze the relation between RLS and hypertension, with adjustment
for age, race, body mass index (BMI), physical activity, menopausal
status, smoking, use of analgesics, oral contraceptive pills, alcohol,
caffeine, folate, and iron along with a score of dietary approaches to stop
hypertension (DASH).
Results: Women with RLS symptoms had higher prevalence of having
hypertension compared to those without symptoms (OR=1.43, 95%
CI: 1.33-1.53; P