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SLEEP 2011 Abstract Supplement

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B. Clinical Sleep Science XIV. Instrumentation and Methodology<br />

0945<br />

DURABILITY, SAFETY, EASE OF USE AND RELIABILITY OF<br />

A TYPE 3 PORTABLE MONITOR AND A SHEET-STYLE TYPE<br />

4 PORTABLE MONITOR<br />

Kadotani H 1,2 , Nakayama-Ashida Y 2 , Nagai Y 1<br />

1<br />

Center for Genomic Medicine, Kyoto University Graduate School of<br />

Medicine, Kyoto, Japan, 2 Horizontal Medical Research Organization,<br />

Kyoto University Graduate School of Medicine, Kyoto, Japan<br />

Introduction: To examine durability, safety, ease of use and reliability<br />

to monitor obstructive sleep apnea syndrome with a type 3 (cardio-respiratory)<br />

and a sheet-style type 4 portable monitors (PMs) in unattended<br />

home settings.<br />

Methods: A cross-sectional survey was conducted to male employees<br />

of a wholesale company in Osaka, Japan (n=139, 44.4 ± 8.36 years).<br />

Participants used either of the two PM on the second and third nights and<br />

both of the PMs on the fourth nights. Ease of use was conducted by a<br />

self-administered questionnaire. Results from the type 3 PM were manually<br />

scored; while those form the type 4 PM were automatically scored.<br />

Results: No safety problems were reported. A few repayments were<br />

needed only for the type 3 PMs. The type 4 PM was more inconvenient<br />

to bring home (type 3: 15.1%; type 4: 68.3%). The type 3 PM was more<br />

inconvenient to use (type 3: 71.2%; type 4: 0.7%) and more uncomfortable<br />

to use (type 3: 81.3%; type 4: 9.4%). Data from 107 and 133 out of<br />

139 participants were comprehensible for both of two recorded nights<br />

with the type 3 and the type 4 PMs, respectively. Blant- Altman plot and<br />

scattered plot revealed high night-to-night reliability of these PMs<br />

Conclusion: The type 3 and the type 4 PMs were durable, safe, easy<br />

to use and reliable. Both the PMs can be used to monitor OSA in unattended<br />

home settings.<br />

Support (If Any): This work was supported by Special Coordination<br />

Funds for Promoting Science and Technology, grants in aid from Ministry<br />

of Health, Labor and Welfare of Japan, and research grants from<br />

PRESTO JST, Suzuken Memorial Foundation, Takeda Science Foundation,<br />

Mitsui Life Social Welfare Foundation, Chiyoda Kenko Kaihatsu<br />

Jigyodan Foundation, and Health Science Center Foundation. We are<br />

grateful to the participants, their family, and their company. Participants<br />

of this study were employees of a company, which has financial interaction<br />

with Kenzmedico.<br />

0946<br />

EVALUATING A NOVEL <strong>SLEEP</strong> DIAGNOSTIC SYSTEM<br />

Verma N 2 , Zheng A 1 , Black J 3 , Ryder P 1<br />

1<br />

Huneo, LLC, Fremont, CA, USA, 2 Washington Township Center for<br />

Sleep Disorders, Fremont, CA, USA, 3 Stanford University, Stanford,<br />

CA, USA<br />

Results: Visual comparison of the raw signals between PSG and the<br />

new system revealed equivalent signal quality in all instances. AHI<br />

scores (according to AASM guidelines) from the first 5 PSG studies<br />

are tabulated below. (Results of the subsequent 7 PSGs are pending.)<br />

Study/AHI (PSG)/AHI (new system) 1/34.7/33.4 2/2.0/2.0 3/4.8/3.8<br />

4/53.4/49.4 5/112.5/103.1<br />

Conclusion: We introduce a novel sleep data collection system with<br />

real-time data viewing, transmitting and analysis capacity. The results<br />

of a limited number of sleep studies from an on-going trial suggest that<br />

data collected from this new system are equivalent to those from the<br />

sleep-lab PSG.<br />

0947<br />

VALIDATION OF A NOVEL <strong>SLEEP</strong> EEG SLOW WAVE<br />

AUTOMATED DETECTION ALGORITHM<br />

Picot A, Van Cauter E, Chapotot F<br />

University of Chicago, Chicago, IL, USA<br />

Introduction: EEG slow waves (SW) are key components of deep<br />

NREM sleep. A previous method to detect SW during sleep stages 3<br />

and 4 has been proposed by Massimini et al. Here we propose a novel<br />

algorithm to detect SW regardless of sleep/wake stages.<br />

Methods: We first detected SW in filtered EEG signals (0.2-4Hz) with<br />

criteria similar to previous methods using the PRANA biosignal processing<br />

environment (PhiTools, France). Next, we introduced an additional<br />

processing stage of the unfiltered signal to discard false positives.<br />

We used a central EEG channel from a total of 191 PSG recordings<br />

collected in young and middle-aged adults using portable or laboratory<br />

systems. Sleep stages were visually score in 20-30s epochs as follows:<br />

29357 wake, 11810 stage 1, 104357 stage 2, 13552 stage 3, 14909 stage<br />

4 and 97164 REM. Non-parametric statistics were performed on the SW<br />

temporal density to assess differences between algorithms, sleep stages<br />

and recording equipments.<br />

Results: Our algorithm detected a total of 230981 SW, as compared to<br />

a total of 302000 using the Massimini method. Ninety-seven percent of<br />

SW were detected in NREM sleep (2.79, 9.78 and 21.39 SW per min<br />

for stages 2, 3 and 4, respectively), with a significant difference between<br />

stages (chi2=602.46, p

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