SLEEP 2011 Abstract Supplement

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B. Clinical Sleep Science XI. Pediatrics (POMS), inquiring about the past 3 days. Paired t-tests compared the 6 validated POMS subscales across SR versus ES. Results: Of 43 subjects, one was nonadherent to the sleep regimen and one failed to complete the POMS. The remaining 41 averaged 6.2 hours of nightly sleep during SR and 8.6 hours during ES (p
B. Clinical Sleep Science XI. Pediatrics examine whether sleep latency is a physiological marker of the severity of the disorder predicting its medical and psychiatric morbidity. 0856 A TEMPORAL RELATION BETWEEN PUBERTAL MATURATION AND THE ADOLESCENT DECLINE IN DELTA ELECTROENCEPHALOGRAM POWER Campbell IG, de Bie E, Davis NM, Feinberg I Psychiatry, UC Davis, Davis, CA, USA Introduction: Electroencephalogram (EEG) power in the 1-4 Hz frequency band during NREM sleep is high across childhood and then declines steeply across adolescence. This reduction in slow wave activity (SWA) is thought to reflect an adolescent brain maturation driven by synaptic pruning. We previously reported that the SWA decline between age 12 and 14 years was related to chronologic age rather than the rate of pubertal maturation. However, we recognized that the timing of the SWA decline might be linked to the timing of pubertal maturation. We can now address this issue with longitudinal data covering ages 9 to 18 years. Methods: Data are from 6 years of semiannual sleep EEG recordings from two cohorts: C9 (n=31), initially age 9, and C12 (n=38), initially age 12 years. SWA was measured as power in the 1-4 Hz band during first 5 hours of NREM sleep. Tanner stage scores of pubertal maturation were determined during a physician’s exam. Non linear mixed effect analysis was used to fit a Gompertz curve to the sigmoidal SWA decline and a logistic curve to the Tanner stage increase. Both analyses indicate the age at which the curve is changing most rapidly. Results: The age of most rapid SWA decline was related to the age of most rapid pubertal increase. The SWA decline occurred 0.72 years earlier (p
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JOURNAL OF SLEEP AND SLEEP DISORDER
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EDITORIAL In June of 1986, roughly
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A. Basic Science I. Pharmacology an
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SLEEP 2011 Abstract Supplement

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