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Dictionary of Evidence-based Medicine.pdf

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<strong>Dictionary</strong> <strong>of</strong> <strong>Evidence</strong>-<strong>based</strong> <strong>Medicine</strong> 127<br />

Primary care trusts (see under Primary care groups)<br />

Primary outcome measure<br />

In a clinical trial, a primary outcome measure is a prospectively defined<br />

outcome which the investigators consider to be <strong>of</strong> primary importance.<br />

Such an outcome can then be used to define the sample size <strong>of</strong> the trial and<br />

to define clinically meaningful changes on which to base judgements as to<br />

whether a treatment is effective or not. Such outcome measures can be<br />

supplemented with secondary outcome measures. The latter can be used<br />

to support the conclusions to be drawn from the primary outcomes or to<br />

generate new hypotheses. 'Primary and secondary outcome measures' are<br />

also used in meta-analyses.<br />

Primary-secondary care interface<br />

The interface between health care workers employed in hospitals on the<br />

one hand and general practice on the other.<br />

Prisoners' dilemma<br />

The prisoners' dilemma is a classic scenario in game theory used to<br />

illustrate how independent decision making can lead to inferior results for<br />

the parties involved. Similar scenarios are widely used to illustrate decision<br />

making by players in an oligopoly (a market dominated by a few firms<br />

which have to consider each other's possible retaliatory actions) (Gibbons<br />

R (1992) A primer in game theory. Harvester Wheatsheaf, Hertfordshire).<br />

Private goods (see under Public goods)<br />

Probabilistic functionalism<br />

Probabilistic functionalism is an approach suggested by Egon Brunswik<br />

for studying and modelling human judgement (Brunswik E (1955) Representative<br />

design and probabilistic theory in a functional psychology.<br />

Psychological Review. 62: 193-217). The approach is <strong>based</strong> on two propositions:<br />

(i) that the chief task <strong>of</strong> psychology is to understand how an<br />

individual functionally relates to his or her environment; (ii) that the<br />

relationships are stochastic or <strong>based</strong> on probabilistic relationships.

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