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Dictionary of Evidence-based Medicine.pdf

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H<br />

Hawthorne effect<br />

This is the term (named after a study <strong>of</strong> industrial efficiency at the<br />

Hawthorne plant in Chicago) used to describe the effect which is induced<br />

by the study itself because subjects react abnormally when they know they<br />

are being observed.<br />

Hazard function<br />

The hazard function, a term used in survival analysis, is a measure <strong>of</strong> the<br />

potential to failure as a function <strong>of</strong> age. Let T be the random variable<br />

representing time to failure or death. The hazard function A,(f ) can then be<br />

written as:<br />

The product k(t)dt is the probability <strong>of</strong> failure in the infinitesimally small<br />

interval t, t + dt given survival at time t. The hazard function can also be<br />

written as:<br />

where /(i) is the probability density function and S(t) = 1 -f(t) = P(T > t) is<br />

the survival function. f(t) is also called the unconditional failure rate, in<br />

contrast to the hazard function which is also referred to as the conditional<br />

failure rate. The reason for this can be seen by comparing the definition <strong>of</strong><br />

f(t) with the hazard function.

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