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Dictionary of Evidence-based Medicine.pdf

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34 <strong>Dictionary</strong> <strong>of</strong> <strong>Evidence</strong>-<strong>based</strong> <strong>Medicine</strong><br />

Nearly all theories in psychology refer to constructs rather than to specific<br />

behaviours (Nunnally JC, Bernstein IH (1994) Psychometric theory. 3rd edn.<br />

McGraw-Hill, New York). Anxiety and intelligence are examples <strong>of</strong><br />

constructs. We cannot measure these directly but have to use surrogate<br />

measures such as the intelligence quotient (IQ) test, with all the associated<br />

problems <strong>of</strong> validity which such an approach brings about.<br />

Consumer surplus<br />

Consumer surplus refers to the difference between what a consumer actually<br />

pays for a good or service and the most that he or she would be willing<br />

to pay.<br />

Contestable market<br />

A contestable market is one in which there are no entry and exit barriers.<br />

Context effect<br />

It is being increasingly recognized that patients' responses to treatments<br />

may be affected by various factors such as how the investigator presents<br />

the interventions. These non-specific effects are referred to as context<br />

effects. To neutralize such effects, randomization, concealed assignment <strong>of</strong><br />

treatment and blinding are used in well-conducted trials. The term 'context<br />

effect' has also been suggested as a better way <strong>of</strong> describing the 'placebo<br />

effect', as the latter has derogatory connotations.<br />

Contingency table<br />

A contingency table is one in which subjects or objects from a group are<br />

assigned to mutually exclusive categories or cells. In other words, each<br />

individual is entered in one cell only. Each cell gives the total number (or<br />

counts) <strong>of</strong> subjects or objects belonging to a subgroup. An example <strong>of</strong> a<br />

contingency table is shown in Table 1.<br />

Table I Contingency table showing hypothetical data from a comparative trial <strong>of</strong> three<br />

drugs on mortality. Each arm <strong>of</strong> the study entered 100 patients<br />

Drug Deaths Survived Total<br />

Drug A<br />

Drug B<br />

Placebo<br />

Total<br />

5<br />

20<br />

40<br />

65<br />

95<br />

80<br />

60<br />

235<br />

100<br />

100<br />

100<br />

300

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