Research Report 2010 - MDC

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Dr. Zsuzsanna IzsvákProf. Dr. Thomas JentschProf. Dr. Helmut KettenmannDr. Markus LandthalerDr. Stefan LechnerProf. Dr. Young-Ae LeeProf. Dr. Ferdinand le NobleProf. Dr. Achim LeutzProf. Dr. Gary R. Lewin (Vorsitzender)PD Dr. Martin LippProf. Dr. Friedrich C. LuftPD Dr. Jochen MeierProf. Dr. Ingo L. MoranoDr. Thomas MüllerProf. Dr. Thoralf NiendorfDr. Cristiane NolteDr. Matthew N. PoyProf. Dr. Nikolaus RajewskyProf. Dr. Fritz G. RathjenDr. Armin RehmDr. Frank RosenbauerProf. Dr. Claus ScheidereitProf. Dr. Peter SchlagDr. Ruth Schmidt-UllrichDr. Björn Christian SchroederDr. Anja SchützDr. Matthias SelbachDr. Jan-Erik SiemensProf. Dr. Thomas SommerDr. Francesca SpagnoliProf. Dr. Ludwig ThierfelderProf. Dr. Erich WankerProf. Dr. Thomas WillnowDr. Jana WolfDr. Ulrike ZieboldProf. Dr. Frauke ZippProf. Dr. Norbert HübnerDr. Inés Ibanez-TallonDr. Zsuzsanna IzsvákProf. Dr. Thomas JentschProf. Dr. Helmut KettenmannDr. Markus LandthalerDr. Stefan LechnerProf. Dr. Young-Ae LeeProf. Dr. Ferdinand le NobleProf. Dr. Achim LeutzProf. Dr. Gary R. Lewin (Vorsitzender)PD Dr. Martin LippProf. Dr. Friedrich C. LuftPD Dr. Jochen MeierProf. Dr. Ingo L. MoranoDr. Thomas MüllerProf. Dr. Thoralf NiendorfDr. Cristiane NolteDr. Matthew N. PoyProf. Dr. Nikolaus RajewskyProf. Dr. Fritz G. RathjenDr. Armin RehmDr. Frank RosenbauerProf. Dr. Claus ScheidereitProf. Dr. Peter SchlagDr. Ruth Schmidt-UllrichDr. Björn Christian SchroederDr. Anja SchützDr. Matthias SelbachDr. Jan-Erik SiemensProf. Dr. Thomas SommerDr. Francesca SpagnoliProf. Dr. Ludwig ThierfelderProf. Dr. Erich WankerProf. Dr. Thomas WillnowDr. Jana WolfDr. Ulrike ZieboldProf. Dr. Frauke Zipp264 Overview
Staff CouncilThe Staff Council is involved in decisions of the MDCBerlin-Buch that concern personnel and staff welfarematters.PersonalratDer Personalrat ist an Entscheidungen des MDC Berlin-Buch beteiligt, welche die personellen und sozialenBelange der Beschäftigten betreffen.Members of the Staff CouncilIngo Kahl (Chair)Carola Bernert (vice chair)Lutz Else (vice chair)Dagmar Gerhard (vice chair)Manuela AdloffGitta BlendingerDr. Oliver DaumkeRobby FechnerDaniela KeynerSiegne KnespelJan TimmBrigitta Wedekind (secr.)Mitglieder des PersonalratesIngo Kahl (Vorsitz)Carola Bernert (stellv. Vorsitz)Lutz Else (stellv. Vorsitz)Dagmar Gerhard (stellv. Vorsitz)Manuela AdloffGitta BlendingerDr. Oliver DaumkeRobby FechnerDaniela KeynerSiegne KnespelJan TimmBrigitta Wedekind (Sekr.)Women’s RepresentativeThe women’s representative is responsible for mattersand measures concerning equal opportunitiesfor women at the MDC. She advises not only in theplanning but also in the decisions of the Board andother organizational units, in particular with regardto personnel, welfare, and organizational decisions.Currently, Dr. Hannelore Haase serves as the MDCwomen’s representative.FrauenvertreterinDie Frauenvertreterin ist für Angelegenheiten und Maßnahmender Gleichstellung der Frauen am MDC zuständig.Sie wird sowohl bei der Planung als auch bei Entscheidungendes Vorstands und anderer Organisationseinheiten,insbesondere bei personellen, sozialen undorganisatorischen Entscheidungen beratend beteiligt.Derzeit nimmt Dr. Hannelore Haase die Funktion derFrauenvertreterin am MDC wahr.Overview 265
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Research Report 2010MAX DELBRÜCK C
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ContentInhaltContentInhalt.........
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Surgical OncologyPeter M. Schlag...
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at the MDC. The role of the institu
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in discovering genes that contribut
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The ECRC offers research space and
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etween disciplines such as biology,
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approaches from bioinformatics/syst
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von Humboldt Foundation (AvH). The
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organization to a larger, multi-fac
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Cardiovascular and Metabolic Diseas
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electrical signals. More recent wor
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Basic Cardiovascular FunctionStruct
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Figure 2: SORLA and sortilin in neu
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Annette Hammes(Delbrück Fellow)Str
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Ingo L. MoranoStructure of the Grou
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Figure 3. Membrane resealing assay
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Michael GotthardtStructure of the G
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Structure of the GroupSalim Seyfrie
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Structure of the GroupFerdinand le
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Francesca M. SpagnoliStructure of t
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Structure of the GroupKai M. Schmid
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Genetics and Pathophysiology of Car
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Figure 2. Planariato experimentally
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Norbert HübnerStructure of the Gro
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Structure of the GroupGroup LeaderF
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Figure 2. Omega-3 fatty acids prote
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Structure of the GroupDominik N. M
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Rainer DietzStructure of the GroupG
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Figure 2. Cardiac-restricted ablati
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Ludwig ThierfelderStructure of the
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standing of the molecular and cellu
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Structure of the GroupThoralf Niend
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Michael BaderStructure of the Group
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Natriuretic peptide systemJens Butt
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Structure of the GroupZsuzsanna Izs
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Young-Ae LeeStructure of the GroupG
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Structure of the GroupMatthias Selb
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Matthew PoyStructure of the GroupGr
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Jana WolfStructure of the GroupGrou
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Structure of the GroupGroup LeaderD
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Cancer Research ProgramKrebsforschu
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are responsible for the emergence o
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tral component of the canonical Wnt
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lead to an aberrant constitutive ac
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How Notch- and TGFβ signaling casc
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tures of the chronic phase in human
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oped a new safeguard that is based
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Graduate StudentsSeda Cöl ArslanCa
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investigation, as is the cause of c
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Graduate StudentsÖzlem Akilli Özt
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onment, the (cancer) stem cell nich
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The pluripotent state of murine and
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In the morula of the early mouse em
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Graduate StudentsRami Hamscho*Qingb
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esis and granulopoiesis. We showed
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URE ∆/∆ mice regularly develope
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PD Dr. Wolfgang Walther (GroupLeade
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For the delivery of naked DNA into
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ACBDMyc and FoxO transcription fact
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Graduate StudentsKatrin BagolaHolge
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Heinemann, we could also identify t
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Above: Tip of chromosom3L showing t
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Graduate StudentsSarbani Bhattachar
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vesicle transport to the Golgi. Our
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acbFigure 1a: EHD2 is tubulatingpho
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KnowledgeProbabilitiesknownPossible
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Graduate and undergraduatestudentsU
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successive oncogenic mutations. We
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CXCR5 drives the development of ect
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Graduate and undergraduatestudentsW
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Graduate andUndergraduate StudentsM
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Angela MensenStefanie WittstockBjö
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deficient mice, both major effector
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ant of CD3 delta coding for a 45-me
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Robert KudernatschLi-Min LiuAna Mil
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Sebastian GüntherTechnical Assista
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Graduate StudentsJana RolffAnnika W
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with murine hepatocytes showed morp
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Function and Dysfunction of the Ner
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The Neuroscience Department also es
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the coming years, Björn Schröder
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mice. Further analysis of the funct
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Signaling Pathways and Mechanisms i
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Control Olig3 -/-ABFigure 2. Geneti
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Thomas J. JentschStructure of the G
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Figure 2. Cellular model for ionic
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Structure of the GroupGroup LeaderF
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paired-pulse facilitation, less dep
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Gary R. LewinStructure of the Group
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Model summarizing the three waves o
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Structure of the GroupInes Ibañez-
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Jochen C. MeierStructure of the Gro
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Björn Christian SchroederStructure
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Structure of the GroupJan Siemens(S
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Structure of the GroupGroup LeaderD
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Imaging of the Living BrainStructur
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Pathophysiological Mechanisms of Ne
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Figure 2. Iba1 positive microglia c
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Erich E. WankerStructure of the Gro
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Scientific-Technical StaffAnja Frit
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Structure of the GroupJan Bieschke(
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Berlin Institute of Medical Systems
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etes, metabolic diseases and neurod
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A number of MDC investigators have
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Technical AssistantsClaudia Langnic
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has become a standardized data flow
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Phylogeny of cellulase genes from P
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Experimental and Clinical Research
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his patients, and a basic research
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The ultrahigh field MR facility was
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Structure of the GroupSimone Spuler
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Ralph KettritzStructure of the Grou
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Structure of the GroupJeanette Schu
Page 240 and 241: Maik GollaschStructure of the Group
Page 243 and 244: Technology PlatformsComputational B
Page 245 and 246: projects/ard/] to detect repeats li
Page 247 and 248: Simulation of line-scan images of C
Page 249 and 250: Development of an MRM method for qu
Page 251 and 252: mobility or turnover of the underly
Page 253 and 254: Left: Inside view of a FACSAria2 (f
Page 255 and 256: Examples fort the use of EM methods
Page 257: Oviducts lined up in pre-implantati
Page 260 and 261: Academic Appointments 2008-2009Beru
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Page 264 and 265: “Bioinformatics in Quantitative B
Page 266 and 267: Delbrück FellowsDelbrück-Stipendi
Page 268 and 269: Yinth Andrea Bernal-Sierra, a PhD s
Page 270 and 271: Congresses and Scientific MeetingsK
Page 272 and 273: SeminarsSeminare2008Speaker Institu
Page 274 and 275: Speaker Institute TitleKiyoshi Mori
Page 276 and 277: 2009Speaker Institute TitleDavid G.
Page 278 and 279: Speaker Institute TitleJuri Rappsil
Page 280 and 281: The Helmholtz AssociationDie Helmho
Page 282 and 283: The Berlin-Buch CampusDer Campus Be
Page 284: the MDC, the existing collaboration
Page 287 and 288: Prof. Dr. Gary R. LewinMDC Berlin-B
Page 289: Prof. Dr. Renato ParoCenter of Bios
Page 293 and 294: Type of Financing/Art der Finanzier
Page 295 and 296: Research Projects 2008-2009Forschun
Page 297 and 298: CIC-5 Regulation und Endocytose am
Page 299 and 300: MDCMAX-DELBRÜCK-CENTRUMFÜR MOLEKU
Page 301 and 302: Index 275Bröske, A. . . . . . . .
Page 303 and 304: Index 277Gross, V. . . . . . . . .
Page 305 and 306: Index 279Kur, E. . . . . . . . . .
Page 307 and 308: Index 281Piano, F. . . . . . . . .
Page 309 and 310: Index 283Smink, J. . . . . . . . .
Page 312 and 313: Campus MapCampusplanRobert-Rössle-
Page 314: How to find your way to the MDCDer
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Research Report 2010 - MDC

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