Research Report 2010 - MDC

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Facts and FiguresFakten und KennzahlenPersonnel / PersonalPersonnel (as of December 31, 2008) / Personalstand in Köpfen mit Stichtag 31.12.2008Total/ limited contract/ permanent/ in-house financing/ third-party financing/Gesamt befristet unbefristet grundfinanziert drittmittelfinanziertScientists (not including PhD students) / 215 182 33 122 93Wissenschaftler (ohne Doktoranden)PhD students / 211 211 0 79 132Doktoranden und studentische HilfskräfteTechnical Assistants (TAs) in the scientific sphere / 190 103 87 129 61Technische Angestellte im wissenschaftlichen BereichOther / Andere 213 52 161 197 16In training / In Ausbildung 51 51 0 51 0Total / Summe 880 599 281 578 302Other*/Andere*24%In training/In Ausbildung6%Technical Assistants/TAs22%26%Scientists (not including PhD students)/Wissenschaftler (ohne Doktoranden)24%PhD Students/DoktorandenType of Employment Contract / Art der Verträgelimited/befristet permanent/unbefristet250200limited/befristetpermanent/unbefristetScientists/Wissenschaftler 182 33PhD Students/Doktoranden. 211 0150Technical Assistants/TAs 103 87Other*/Andere* 52 161100In training/Ausbildung 51 050*Infrastructure, administration, and technology transfer*Infrastruktur, Verwaltung und Technologietransfer0Scientists/ PhD Students/ TechnicalWissenschaftler Doktoranden Assistants/TAsOther*/Andere*In training/Ausbildung266 Overview
Type of Financing/Art der Finanzierungin-house financing/grundfinanziertthird-party financing/drittmittelfinanziert250200in-house financing/grundfinanziertthird-party financing/drittmittelfinanziertScientists/Wissenschaftler 122 93PhD Students/Doktoranden 79 132Technical Assistants/TAs 129 61Other*/Andere* 197 16In training/Ausbildung 51 0150100500Scientists/ PhD TechnicalWissenschaftler Students/ Assistants/TAsDoktorandenOther*/Andere*In training/AusbildungFinancing / FinanzierungCosts of research programs in 2008 (in thousands of €) / Kosten der Forschungsprogramme 2008 in T€Programs & Categories / Programme & KategorienCosts / KostenCancer Research/Krebsforschung 13.806Cardiovascular and metabolic diseases/Herz- Kreislauf- und Stoffwechselerkrankungen 16.696Function and dysfunction of the nervous system/Funktion und Dysfunktion des Nervensystems 6.791Comparative Genomics/Vergleichende Genomforschung 259Independent Research/Programmungebundene Forschung 134Technology transfer/Technologietransfer 1.116Special work (training)/Sonderaufgaben 2.666Centre Management/ 4.427Scientific infrastructure and basic operation/ 5.745Total/Gesamt 51.640Scientific infrastructure and basic operation/Infrastruktur und BasisbetriebCentre Management/Verwaltung11%Special work (training)/Sonderaufgaben9%27%Cancer Research/KrebsforschungTechnology transfer/Technologietransfer 2%Independent Research/0,3%Programmungebundene Forschung0,5%Comparative Genomics/Vergleichende GenomforschungFunction and dysfunction of the nervous system/Funktion und Dysfunktion des Nervensystems5%13%32%Cardiovascular and metabolic diseases/Herz- Kreislauf- und StoffwechselerkrankungenOverview 267
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Research Report 2010MAX DELBRÜCK C
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ContentInhaltContentInhalt.........
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Surgical OncologyPeter M. Schlag...
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at the MDC. The role of the institu
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in discovering genes that contribut
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The ECRC offers research space and
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etween disciplines such as biology,
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approaches from bioinformatics/syst
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von Humboldt Foundation (AvH). The
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organization to a larger, multi-fac
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Cardiovascular and Metabolic Diseas
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electrical signals. More recent wor
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Basic Cardiovascular FunctionStruct
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Figure 2: SORLA and sortilin in neu
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Annette Hammes(Delbrück Fellow)Str
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Ingo L. MoranoStructure of the Grou
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Figure 3. Membrane resealing assay
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Michael GotthardtStructure of the G
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Structure of the GroupSalim Seyfrie
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Structure of the GroupFerdinand le
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Francesca M. SpagnoliStructure of t
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Structure of the GroupKai M. Schmid
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Genetics and Pathophysiology of Car
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Figure 2. Planariato experimentally
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Norbert HübnerStructure of the Gro
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Structure of the GroupGroup LeaderF
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Figure 2. Omega-3 fatty acids prote
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Structure of the GroupDominik N. M
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Rainer DietzStructure of the GroupG
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Figure 2. Cardiac-restricted ablati
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Ludwig ThierfelderStructure of the
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standing of the molecular and cellu
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Structure of the GroupThoralf Niend
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Michael BaderStructure of the Group
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Natriuretic peptide systemJens Butt
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Structure of the GroupZsuzsanna Izs
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Young-Ae LeeStructure of the GroupG
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Structure of the GroupMatthias Selb
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Matthew PoyStructure of the GroupGr
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Jana WolfStructure of the GroupGrou
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Structure of the GroupGroup LeaderD
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Cancer Research ProgramKrebsforschu
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are responsible for the emergence o
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tral component of the canonical Wnt
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lead to an aberrant constitutive ac
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How Notch- and TGFβ signaling casc
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tures of the chronic phase in human
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oped a new safeguard that is based
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Graduate StudentsSeda Cöl ArslanCa
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investigation, as is the cause of c
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Graduate StudentsÖzlem Akilli Özt
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onment, the (cancer) stem cell nich
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The pluripotent state of murine and
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In the morula of the early mouse em
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Graduate StudentsRami Hamscho*Qingb
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esis and granulopoiesis. We showed
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URE ∆/∆ mice regularly develope
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PD Dr. Wolfgang Walther (GroupLeade
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For the delivery of naked DNA into
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ACBDMyc and FoxO transcription fact
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Graduate StudentsKatrin BagolaHolge
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Heinemann, we could also identify t
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Above: Tip of chromosom3L showing t
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Graduate StudentsSarbani Bhattachar
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vesicle transport to the Golgi. Our
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acbFigure 1a: EHD2 is tubulatingpho
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KnowledgeProbabilitiesknownPossible
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Graduate and undergraduatestudentsU
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successive oncogenic mutations. We
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CXCR5 drives the development of ect
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Graduate and undergraduatestudentsW
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Graduate andUndergraduate StudentsM
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Angela MensenStefanie WittstockBjö
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deficient mice, both major effector
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ant of CD3 delta coding for a 45-me
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Robert KudernatschLi-Min LiuAna Mil
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Sebastian GüntherTechnical Assista
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Graduate StudentsJana RolffAnnika W
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with murine hepatocytes showed morp
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Function and Dysfunction of the Ner
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The Neuroscience Department also es
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the coming years, Björn Schröder
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mice. Further analysis of the funct
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Signaling Pathways and Mechanisms i
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Control Olig3 -/-ABFigure 2. Geneti
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Thomas J. JentschStructure of the G
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Figure 2. Cellular model for ionic
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Structure of the GroupGroup LeaderF
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paired-pulse facilitation, less dep
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Gary R. LewinStructure of the Group
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Model summarizing the three waves o
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Structure of the GroupInes Ibañez-
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Jochen C. MeierStructure of the Gro
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Björn Christian SchroederStructure
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Structure of the GroupJan Siemens(S
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Structure of the GroupGroup LeaderD
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Imaging of the Living BrainStructur
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Pathophysiological Mechanisms of Ne
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Figure 2. Iba1 positive microglia c
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Erich E. WankerStructure of the Gro
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Scientific-Technical StaffAnja Frit
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Structure of the GroupJan Bieschke(
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Berlin Institute of Medical Systems
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etes, metabolic diseases and neurod
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A number of MDC investigators have
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Technical AssistantsClaudia Langnic
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has become a standardized data flow
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Phylogeny of cellulase genes from P
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Experimental and Clinical Research
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his patients, and a basic research
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The ultrahigh field MR facility was
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Structure of the GroupSimone Spuler
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Ralph KettritzStructure of the Grou
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Structure of the GroupJeanette Schu
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Maik GollaschStructure of the Group
Page 243 and 244: Technology PlatformsComputational B
Page 245 and 246: projects/ard/] to detect repeats li
Page 247 and 248: Simulation of line-scan images of C
Page 249 and 250: Development of an MRM method for qu
Page 251 and 252: mobility or turnover of the underly
Page 253 and 254: Left: Inside view of a FACSAria2 (f
Page 255 and 256: Examples fort the use of EM methods
Page 257: Oviducts lined up in pre-implantati
Page 260 and 261: Academic Appointments 2008-2009Beru
Page 262 and 263: Buch which is part of the Excellenc
Page 264 and 265: “Bioinformatics in Quantitative B
Page 266 and 267: Delbrück FellowsDelbrück-Stipendi
Page 268 and 269: Yinth Andrea Bernal-Sierra, a PhD s
Page 270 and 271: Congresses and Scientific MeetingsK
Page 272 and 273: SeminarsSeminare2008Speaker Institu
Page 274 and 275: Speaker Institute TitleKiyoshi Mori
Page 276 and 277: 2009Speaker Institute TitleDavid G.
Page 278 and 279: Speaker Institute TitleJuri Rappsil
Page 280 and 281: The Helmholtz AssociationDie Helmho
Page 282 and 283: The Berlin-Buch CampusDer Campus Be
Page 284: the MDC, the existing collaboration
Page 287 and 288: Prof. Dr. Gary R. LewinMDC Berlin-B
Page 289 and 290: Prof. Dr. Renato ParoCenter of Bios
Page 291: Staff CouncilThe Staff Council is i
Page 295 and 296: Research Projects 2008-2009Forschun
Page 297 and 298: CIC-5 Regulation und Endocytose am
Page 299 and 300: MDCMAX-DELBRÜCK-CENTRUMFÜR MOLEKU
Page 301 and 302: Index 275Bröske, A. . . . . . . .
Page 303 and 304: Index 277Gross, V. . . . . . . . .
Page 305 and 306: Index 279Kur, E. . . . . . . . . .
Page 307 and 308: Index 281Piano, F. . . . . . . . .
Page 309 and 310: Index 283Smink, J. . . . . . . . .
Page 312 and 313: Campus MapCampusplanRobert-Rössle-
Page 314: How to find your way to the MDCDer
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Research Report 2010 - MDC

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