section 1 - World Intellectual Property Organization

37/2000
14 Sep/sep 2000 PCT Gazette - Section I - Gazette du PCT 13243
(81) AE AL AM AT AU AZ BA BB BG BR BY
CA CH CN CR CU CZ DE DK DM EE ES
FI GB GD GE GH GM HR HU ID IL IN
IS JP KE KG KR KZ LC LK LR LS LT LU
LV MA MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM
TR TT TZ UA UG US UZ VN YU ZA ZW;
AP (GH GM KE LS MW SD SL SZ TZ UG
ZW); EA (AM AZ BY KG KZ MD RU TJ
TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF
BJ CF CG CI CM GA GN GW ML MR NE
SN TD TG).
Published / Publiée :(c)
(51) 7 C07D 473/16, 473/18, A61K 31/52,
31/522
(11) WO 00/53603 (13) A1
(21) PCT/US00/06250
(22) 10 Mar/mar 2000 (10.03.2000)
(25) en (26) en
(30) 09/267,839 12 Mar/mar 1999
(12.03.1999)
US
(43) 14 Sep/sep 2000 (14.09.2000)
(54) 2–HYDROXY METHYLCYCLOPRO
PYLIDENEMETHYL PURINES AND
–PYRIMIDINES AS ANTIVIRAL
AGENTS
2–HYDROXY METHYLCYCLOPRO
PYLIDENEMETHYL PURINES ET
PYRIMIDINES COMME AGENTS AN-
TIVIRAUX
(71) THE REGENTS OF THE UNIVERSITY
OF MICHIGAN [US/US]; Wolverine Tower,
Room 2071, 3003 S. State Street,
Ann Arbor, MI 48109–1280 (US). WAYNE
STATE UNIVERSITY [US/US]; 656 W.
Kirby, 4249 F.A.B, Detroit, MI 48202 (US).
(72) ZEMLICKA, Jiri; 2025 Common, Warren,
MI 48092 (US). QIU, Yao–Ling; Apartment
#1304, 5200 Anthony Wayne Drive, Detroit,
MI 48202 (US). DRACH, John, C.; 1372
Barrister Road, Ann Arbor, MI 48105 (US).
PTAK, Roger, G.; Apartment #103, 741
Valley Circle Drive, Saline, MI 48176 (US).
(74) SMITH, DeAnn, F. et al. / etc.; Lahive &
Cockfield, LLP, 28 State Street, Boston, MA
02109 (US).
(81) CA JP; EP (AT BE CH CY DE DK ES FI
FR GB GR IE IT LU MC NL PT SE).
(51) 7 C07D 473/34, 487/04, 211/78, 207/34,
A61K 31/52, 31/519, A61P 43/00, 25/24,
25/22, 25/28, 25/16, 25/30, 25/08, 1/00,
7/10, 9/10, 9/12, 17/02, 29/00, 37/02
(11) WO 00/53604
(21) PCT/JP00/01468
(13) A1
(22) 10 Mar/mar 2000 (10.03.2000)
(25) ja (26) ja
(30) 11/65004 11 Mar/mar 1999
(11.03.1999)
JP
(30) 11/185628 30 Jun/juin 1999
(30.06.1999)
(30) 11/258353 13 Sep/sep 1999
(13.09.1999)
JP
JP
(43) 14 Sep/sep 2000 (14.09.2000)
(54) CARBAMOYL TETRAHYDROPYRI-
DINE DERIVATIVES
DERIVES DE CARBAMOYL TETRA-
HYDROPYRIDINE
(71) TAISHO PHARMACEUTICAL CO.,
LTD. [JP/JP]; 24–1, Takata 3–chome, Toshima–ku,
Tokyo 170–8633 (JP).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) NAKAZATO, Atsuro [JP/JP]; Taisho
Pharmaceutical Co., Ltd., 24–1, Takata
3–chome, Toshima–ku, Tokyo 170–8633
(JP). OKUBO, Taketoshi [JP/JP]; Taisho
Pharmaceutical Co., Ltd., 24–1, Takata
3–chome, Toshima–ku, Tokyo 170–8633
(JP). KUMAGAI, Toshihito [JP/JP]; Taisho
Pharmaceutical Co., Ltd., 24–1, Takata
3–chome, Toshima–ku, Tokyo 170–8633
(JP). TOMISAWA, Kazuyuki [JP/JP]; Taisho
Pharmaceutical Co., Ltd., 24–1, Takata
3–chome,
(JP).
Toshima–ku, Tokyo 170–8633
(74) KITAGAWA, Tomizo; Taisho Pharmaceutical
Co., Ltd., Patent Division, 24–1, Takata
3–chome,
(JP).
Toshima–ku, Tokyo 170–8633
(81) AU CA CN KR US; EP (AT BE CH CY DE
DK ES FI FR GB GR IE IT LU MC NL PT
SE).
(51) 7 C07D 487/04, A61K 31/519
(11) WO 00/53605 (13) A1
(21) PCT/US00/05903
(22) 8 Mar/mar 2000 (08.03.2000)
(25) en (26) en
(30) 60/123,902 11 Mar/mar 1999 US
(11.03.1999)
(43) 14 Sep/sep 2000 (14.09.2000)
(54) TYROSINE KINASE INHIBITORS
INHIBITEURS DE TYROSINE KINASE
(71) MERCK & CO., INC. [US/US]; 126 East
Lincoln Avenue, Rahway, NJ 07065–0907
(US).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) BILODEAU, Mark, T. [US/US];
126 East Lincoln Avenue, Rahway, NJ
07065–0907 (US). FRALEY, Mark, E.
[US/US]; 126 East Lincoln Avenue, Rahway,
NJ 07065–0907 (US). HUNGATE,
Randall, W. [US/US]; 126 East Lincoln
Avenue, Rahway, NJ 07065–0907 (US).
(74) MERCK & CO., INC.; 126 East Lincoln
Avenue, Rahway, NJ 07065–0907 (US).
(81) AE AL AM AT AU AZ BA BB BG BR BY
CA CH CN CR CU CZ DE DK DM DZ EE
ES FI GB GD GE GH GM HR HU ID IL IN
IS JP KE KG KR KZ LC LK LR LS LT LU
LV MA MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM
TR TT TZ UA UG US UZ VN YU ZA ZW;
AP (GH GM KE LS MW SD SL SZ TZ UG
ZW); EA (AM AZ BY KG KZ MD RU TJ
TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF
BJ CF CG CI CM GA GN GW ML MR NE
SN TD TG).
Published / Publiée :(c)
(51) 7 C07D 491/04, A61K 31/44, C07D 213/66,
A61P 9/00
(11) WO 00/53606 (13) A1
(21) PCT/IB00/00255
(22) 7 Mar/mar 2000 (07.03.2000)
(25) en (26) en
(30) 60/123,698 8 Mar/mar 1999
(08.03.1999)
(30) 60/125,881 24 Mar/mar 1999
(24.03.1999)
(43) 14 Sep/sep 2000 (14.09.2000)
US
US
(54) PYRIDOXAL ANALOGUES FOR VI-
TAMIN B–6 DISORDERS
ANALOGUES DE PYRIDOXAL DES-
TINES AUX TROUBLES PROVOQUES
PAR UNE CARENCE EN VITAMINE
B6
(71) MEDICURE INC. [CA/CA]; 62 Scurfield
Boulevard, Winnipeg, Manitoba R3Y 1M5
(CA).
(72) HAQUE, Wasimul; 4832 17th Avenue,
Edmonton, Alberta T6L 2Y7 (CA).
(74) DUBUC, Jean, H. et al. / etc.; Goudreau
Gage Dubuc, The Stock Exchange Tower,
800 Place Victoria, Suite 3400, P.O. Box 242,
Montreal, Quebec H4Z 1E9 (CA).
(81) AE AL AM AT AT (Utility model / modèle
d’utilité) AUAZBABBBGBRBYCACH
CN CR CU CZ CZ (Utility model / modèle
d’utilité) DE DE (Utility model / modèle
d’utilité) DK DK (Utility model / modèle
d’utilité) DM EE EE (Utility model / modèle
d’utilité) ES FI FI (Utility model / modèle
d’utilité) GBGDGEGHGMHRHUIDIL
IN IS JP KE KG KP KR KR (Utility model
/ modèle d’utilité) KZLCLKLRLSLTLU
LV MA MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SK (Utility
model / modèle d’utilité) SLTJTMTRTT
TZ UA UG UZ VN YU ZA ZW; AP (GH
GM KE LS MW SD SL SZ TZ UG ZW);
EA (AM AZ BY KG KZ MD RU TJ TM);
EP (AT BE CH CY DE DK ES FI FR GB
GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
(51) 7 C07D 491/22, A61K 31/435 // (C07D
491/22, 311:00, 221:00, 221:00, 209:00)
(11) WO 00/53607 (13) A1
(21) PCT/EP00/01570
(22) 8 Mar/mar 2000 (08.03.2000)
(25) en (26) en
(30) 99830124.6 9 Mar/mar 1999
(09.03.1999)
(43) 14 Sep/sep 2000 (14.09.2000)
EP
(54) CAMPTOTHECIN DERIVATIVES HA-
VING ANTITUMOR ACTIVITY
DERIVES DE CAMPTOTHECINE
AYANT UNE ACTION ANTITUMO-
RALE