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Mathematics in Independent Component Analysis

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1.6. Applications to biomedical data analysis 49<br />

<strong>Component</strong> given by each method [a.u.]<br />

(a) JADE<br />

(b) NMF<br />

(c) NMF*<br />

(d) sNMF<br />

(e) sNMF*<br />

(f) SCA<br />

(g) s-EMG<br />

-2<br />

-4<br />

02468<br />

-2<br />

-4<br />

02468<br />

-2 02468<br />

-2 0246<br />

-2 02468<br />

-2<br />

-4<br />

02468<br />

0.5 1<br />

1.5<br />

-0.5 0<br />

50 100 150 200 250 300 350 400 450 500<br />

Time [ms]<br />

Figure 1.27: A recovered sources after unmix<strong>in</strong>g an sEMG data, (a-f) shows results obta<strong>in</strong>ed<br />

us<strong>in</strong>g the different methods and (g) the orig<strong>in</strong>al most-active sensor signal.<br />

Our approach was therefore to apply and validate sparse BSS methods based on various<br />

model assumptions to sEMG signals. When applied to artificial signals we found noticeable<br />

differences of algorithm performance depend<strong>in</strong>g on the source assumptions. In particular, sparse<br />

nonnegative matrix factorization outperforms the other methods with regards to <strong>in</strong>creas<strong>in</strong>g<br />

additive noise. However, <strong>in</strong> the case of real sEMG signals we showed that despite the fundamental<br />

differences <strong>in</strong> the various models, the methods yield rather similar results and can successfully<br />

separate the source signal, see figure 1.27. This was due to the fact that the different sparseness<br />

assumptions are only approximately fulfilled thus apparently forc<strong>in</strong>g the algorithms to reach<br />

similar results, but from different <strong>in</strong>itial conditions us<strong>in</strong>g different optimization criteria.<br />

The result<strong>in</strong>g sparse signal components can now be used for further analysis and for artifact<br />

removal. A similar analysis us<strong>in</strong>g spectral correlations have been employed <strong>in</strong> (Böhm et al.,<br />

2006, Stadlthanner et al., 2006b) to remove the water artifact from multidimensional proton<br />

NMR spectra of biomolecules dissolved <strong>in</strong> aqueous solutions.

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