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Sustainable Agriculture Literature Review - Boulder County

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potential into a food crop. The second category, which represents an intermediate risk, is<br />

the potential for altering or replacing the endogenous allergenicity (the insertion of new<br />

genetic material which can cause a change in the level of allergenic proteins normally<br />

found) of a GE crop, which would cause an increased concern for already allergic<br />

patients. The last category, which has received attention as of late, involves expression<br />

of new proteins that may become allergens in man but generally represents a relatively<br />

low risk to the consumer. 803<br />

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Figure 41: Methods for Genetically Altering Plants 804<br />

(Adapted from the National Academy of Sciences)<br />

When a gene is transferred from a source of known allergenic potential, the assessment<br />

of the allergenicity of the GM crop is relatively straightforward. Similarly, it is relatively<br />

easy to assess the effect of genetic engineering on endogenous allergens in crops with<br />

some evidence of allergenicity. There are several examples of this happening, such as<br />

the demonstration of the allergenicity of the Brazil nut when used to enhance the<br />

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