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Sustainable Agriculture Literature Review - Boulder County

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Insect resistance of the protein trait Bt decreases the efficiency of Bt crops and their<br />

projected benefits. Insecticidal crystal proteins, also considered toxins, from Bt are the<br />

basis of defense against targeted insects. Although there is now variation in the crystal<br />

proteins used in GE crops, some proteins, such as Cry1AB and Cry1Ac, are very similar<br />

and therefore insects that become resistant to one can be resistant to the other. The first<br />

generation of Bt crops only contained a single type of toxin throughout the growing<br />

season. Consequently, the continuous “exposure to Bt toxins represents one of the<br />

largest, most sudden selections for resistance experiences by insects.” 593 In laboratory<br />

tests, many strains of major pests have evolved with a resistance to Bt toxins. This insect<br />

resistance evolved because Bt crops continuously produce toxins, whereas Bt toxin sprays<br />

degrade quickly making evolutionary resistance slow and unlikely. The evolution of<br />

resistance to Bt sprays and crops outside of the laboratory is documented for only two<br />

lepidopteran pests. Evolutionary resistance is a major threat to the future success of Bt<br />

crops. 594 For more information, see section 7.3 Pesticide Resistance<br />

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