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Introduction - Uppsala Monitoring Centre

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She then did bid me drop in her eyes<br />

A sovereign water sent her that day,<br />

But I had a liquor I more did prize,<br />

Made of Henbane and Mercury steep’d in Whey:<br />

I dropt it in and nointed her face,<br />

Which brought her into a most devillish case:<br />

For she rore and she ranted, and well she might;<br />

For after that time she ne’er had sight.<br />

Then did get her a dog and a bell,<br />

To lead her about from place to place:<br />

And now ‘tis, husband, I hope you are well;<br />

But before it was cuckold and rogue to my face;<br />

Then blest be that Henbane and Mercury strong,<br />

That made such a change in my wives tongue.<br />

You see ‘tis a medicine certain and sure,<br />

For the cure of a scold, but I’ll say no more.<br />

1672 The law of the 4 th December 1672 in Denmark-Norway assigned<br />

physicians control over both apothecaries and midwives and<br />

physicians who were obliged to provide free medical care to the<br />

poor. At that time there were only 5 physicians in the country<br />

(Hubbard, 2006).<br />

1673 ‘Presque tous les hommes meurent de leurs remèdes, et non pas de<br />

leurs maladies.’ [Nearly all men die of their medicines, not of their<br />

diseases]. ‘La Malade Imaginaire’ Molière (1622–1673). Molière also<br />

observed that ‘medicine is only for those who are fit enough to<br />

survive the treatment as well as the illness.’<br />

1676 Charas, Moyse, 1619–1698, ‘Pharmacopée Royale Galénique et<br />

Chymique’ [Royal Pharmacopoeia for apothecaries and Chemists] (A<br />

Paris, M.DC.LXXVI..)’ No mention of ADRs for opium, despite the<br />

fact that he experimented with opium on himself. He came to London<br />

as a Huguenot refugee in 1680, but later converted to Catholicism<br />

and returned to France<br />

Mercury: ‘… and because mercury passes for a medicament<br />

which is a great enemy of the nerves’ ... ’although sometimes it<br />

excites the salivation in delicate persons’… from whence it can make<br />

a great ravage in the stomach.’<br />

Henbane (semenis hyosciami albi) ‘I admit also that the roots of<br />

Henbane eaten in quantity upsets for a time the judgement and<br />

troubles the reason.’<br />

1678 ‘Experiments and Observations of the Effects of Several Sorts of

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