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Introduction - Uppsala Monitoring Centre

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types of hellebore. There was a gap of 700 years from 873 to 1491 without any<br />

reports of toxicity.<br />

Those AEs reported prior to 1000 AD: death, thirst, mouth and throat burning,<br />

swelling of tongue and throat, shivering, trembling, vomiting, diarrhoea, burning in<br />

the stomach, convulsion, palpitation of the heart, somnolence, and itching.<br />

Late arrivals – after 1800: salivation, stupor, collapse, precordial oppression,<br />

heart failure, dizziness, watery eyes, dimness of vision, dilated pupils, difficulty in<br />

swallowing, headache and tinnitus. (those in italics first described by Hahnemann).<br />

It is difficult to find any reason why those reported after 1800 should not have<br />

been discovered earlier.<br />

Present day evidence emphasises salivation, burning in the mouth and throat as<br />

well as bradycardia. Again the different phraseology makes it difficult to know<br />

whether the ancients were describing the same thing as the modern writers. Reports<br />

by different authors tend to confirm that an event was caused by the drug, but<br />

several authors have been known to copy verbatim from previous authors so it is not<br />

absolute confirmation.<br />

Chapter 10. Henbane<br />

ndications: inflammation, gout, pain, eye diseases, to stop bleeding, palpitations,<br />

I<br />

excessive lacrimation, helping eyelids to grow, toothache, earache, insanity,<br />

epilepsy, and black bile (Lev & Amar, 2008).<br />

Table 5. Adverse reactions to Henbane<br />

* = Scopolamine bold type indicates a symptom mentioned in aphorism<br />

Dry<br />

mouth/throat<br />

1756 x x<br />

Thirst 1729, 1763 x x x

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