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Introduction - Uppsala Monitoring Centre

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gram (EPG) of faeces of an Oe. stephanostomum infection could be measured; it<br />

fell from 130 to 15 in 20 hours (Huffman, 2001).<br />

Most domestic or wild ungulates 6 that graze on rangelands with poisonous plants<br />

do not succumb to these plants. Animals can cope with poisonous plants, using both<br />

behavioural and physiological adaptations. Behavioural mechanisms converge on<br />

postingestive feedback and aversive conditioning, as animals learn which plants<br />

cause illness. Physiological mechanisms centre on detoxifying plant compounds in<br />

the gut by rumen microbes or in the liver through enzymatic reactions that allow<br />

toxins to be excreted. Domestic livestock are more often made ill or killed by toxic<br />

plants than are wild ungulates, probably because wild animals have more<br />

developed avoidance or detoxifying capabilities than do livestock (Pfister, 1999).<br />

Stone Age - Middle Palaeolithic (180,000 - 22,000)<br />

Evidence of the use of herbal remedies goes back some 60,000 years<br />

to the Shanidar burial site at the foothills of the Zagros Mountains in<br />

north-eastern Iraq, where the remains of a Neanderthal man were<br />

uncovered in 1960 by Ralph Solecki (Solecki, 1975). Here there were<br />

what appeared to be ordinary human bones 60-80,000 years old and<br />

plant remains surrounded the dead man. Study of the plants suggested<br />

that the plants may have been chosen for their specific medicinal<br />

properties. Yarrow, cornflower, bachelor’s button, St. Barnaby’s thistle,<br />

ragwort or groundsel, grape hyacinth, joint pine or woody horsetail and<br />

hollyhock were represented in the pollen samples, Achillea-type,<br />

Centaurea solstitialis, Senecio-type, Muscari-type, Ephedra altissima,<br />

and Althea-type, all of which have medicinal properties. There was also<br />

evidence of alcohol use, seeds belonging to the psfraisis plant, used in<br />

pits and fermented to produce a primitive alcoholic drink, were found in<br />

abundance next to the burial site (Lietava, 1992; Sommer, 1999).<br />

25,000–13,000 BC<br />

Medicinal plants were depicted at Lascaux, France, where the rock<br />

paintings in the caves have been radiocarbon dated to 13,000–<br />

25,000 BC. The Well Scene probably shows a shaman 7 in a trance<br />

state induced by psychedelic substances.<br />

Stone Age – Neolithic Age (7,000 BC)<br />

7000–5000 BC In the rock cave paintings in the Tassili-n-Ajjer Mountains in southern<br />

6 Ungulates = hoofed mammals<br />

7 Shaman = person having access to the world of good and evil spirits

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