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Introduction - Uppsala Monitoring Centre

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drugs. It represents the first government-published prescription book<br />

in the world. The Imperial Bureau of Medicine established the<br />

department of drug manufacturing.<br />

1116 ‘Bencao Yan Yi’ [Extension of materia medica] by Kou Zong-Shi.<br />

1111–1117 Cao Zongxiao and other medical officers of the Song dynasty wrote<br />

‘Shengji Zonglu’ [General catalogue of divine assistance] This book<br />

lists 20,000 prescriptions and describes the causes, symptoms and<br />

cures for different illnesses (http://www.shennong.com/eng/history/chronology.html.)<br />

www. Accessed 7 th April<br />

2013.<br />

1100s Variolation was developed, which involved the inoculation of children<br />

and adults with dried scab material from smallpox patients. Variolation<br />

was practiced in Turkey, Africa, China, and Europe.<br />

c1123 Foundation of St Bartholomew’s Hospital in London.<br />

1140 The ‘Antidotarium Salernitanum’ [Remedies from Salerno] is one of<br />

the more famous works of the first medical school at Salerno in<br />

Southern Italy–Schola Medica Salernitana, which was founded in<br />

c820 AD. It is a rich collection of recipes for the preparation of<br />

medicines, their application and action. It was not only the basis for all<br />

later pharmacopoeias, but also the first witness on the separation of<br />

medicine and pharmacy. The ‘Antidotarium Nicolai’ [Nicolaus’s book<br />

of antidotes] was written in two versions (for physicians and for<br />

pharmacists) by an unknown Salernitan 34 physician, Nicolaus<br />

Salernitanus, about 1140. Also at Salerno there was a monk from<br />

Carthage, Constantinus Africanus (1020–1087) who translated Arabic<br />

and ancient Greek works into Latin, including ‘Viaticum’. Roger of<br />

Salerno wrote ‘Practica Chirurgiae’ [Practice of surgery] in 1180 and<br />

described the use of quicksilver (argent vif) in ointment for chronic<br />

skin diseases (Jovic, 2004; Abramowitz, 1934).<br />

Regimen Sanitatis Salernitanum:<br />

‘The willow’s juice kills worms when poured into their ears; Its bark<br />

cooked in vinegar cures warts;’ (salicylic acid is still used for warts).<br />

‘The juice of the fruits and the flower are harmful to human<br />

reproduction.’<br />

It also mentions hellebore and henbane.<br />

Roger II, King of the Two Sicilies 35 , promulgated the first known law<br />

34 Saliternitan = native of Salerno, Italy<br />

35 Two Scilies = Sicily and the lower half of Italy

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