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Introduction - Uppsala Monitoring Centre

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(http://www.greekmedicine.net/whos_who/Aristotle.html).<br />

370 BC Hippocrates (c460–370 BC) advocated an underlying theory of<br />

disease based on the four humours (blood, yellow bile, black bile and<br />

phlegm) and the four elements (earth, fire, water, air) with their pairs<br />

of associated qualities (wet and dry, hot and cold). Imbalances of<br />

one element led to an increase in the production of its associated<br />

humour, causing disease (Cahill, 2005). Belief in the ‘humours’<br />

lasted into the early 20 th century, and the humours were responsible<br />

for the practices of bloodletting, emesis and purging, which<br />

tormented patients over the centuries.<br />

Hippocrates first reported adverse reactions to cow’s milk around<br />

370 BC. It is often quoted that Hippocrates said ‘Primum non<br />

nocere’. This is unsubstantiated and similarly Galen and Ambrose<br />

Paré have been cleared of responsibility (Smith, 2005). The actual<br />

phrase was coined by Thomas Inman in 1860. However, it is the<br />

opinion of many scholars that Hippocrates did, in fact, state a similar<br />

the phrase, but did so in his Epidemics, Book. I, Section. XI. One<br />

translation reads: ‘Declare the past, diagnose the present, foretell the<br />

future; practice these acts. As to diseases, make a habit of two<br />

things — to help, or at least to do no harm’. Although this is an<br />

exhortation or command it should be interpreted as a hope. Whether<br />

the translation is accurate and it really means ‘ make a habit…to do<br />

no harm’ is questionable. There must have always been a balanced<br />

judgement as to whether any action might cause harm or benefit.<br />

‘Cutting off of a doctor’s hands’ if he caused the patient to die only<br />

happened, one hopes, if the doctor was negligent. Now, of course,<br />

‘We must operate on sensible risk/benefit principles’ (Shelton, 2000).<br />

Hippocrates recommended chewing willow leaves for analgesia in<br />

childbirth. He was familiar with blood-letting.<br />

Hippocrates’ aphorisms:<br />

‘In acute diseases employ drugs very seldom and only at the<br />

beginning. Even then, never prescribe until you have made a<br />

thorough examination of the patient.’<br />

‘Drugs may be administered to pregnant women from the<br />

fourth to the seventh month of gestation.’ (Chadwick & Mann,<br />

1950)<br />

‘Leave your drugs in the chemist’s pot if you can heal the<br />

patient with food.’<br />

37. ‘Purgative medicines agree ill with persons in good health.’

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