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MAGICAL MEDICINE: HOW TO MAKE AN ILLNESS ... - Invest in ME

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37<br />

Those studies, however, have been str<strong>in</strong>gently and repeatedly criticised <strong>in</strong> the medical literature as be<strong>in</strong>g<br />

methodologically flawed.<br />

The only issue for the Wessely School seems to be how to achieve the implementation of CBT/GET for the<br />

whole range of “medically unexpla<strong>in</strong>ed fatigue” – <strong>in</strong>to which the Wessely School have <strong>in</strong>correctly subsumed<br />

<strong>ME</strong> ‐‐ throughout the nation and beyond, <strong>in</strong>clud<strong>in</strong>g the United States and New Zealand.<br />

It is a matter of record that when serious errors and misrepresentations <strong>in</strong> Wessely’s published articles have<br />

been po<strong>in</strong>ted out to him and to Editors (which, when challenged, even Wessely himself cannot rationally<br />

condone), he blames his peer‐reviewers.<br />

One <strong>in</strong>stance of this occurred <strong>in</strong> 1997 <strong>in</strong> relation to his article <strong>in</strong> the Quarterly Journal of Medic<strong>in</strong>e (The<br />

prognosis of chronic fatigue and chronic fatigue syndrome: a systematic review. Joyce J, Hotopf M, Wessely<br />

S. Q J Med 1997:90:223‐233), the many flaws of which were exposed by research methodologist Dr Terry<br />

Hedrick <strong>in</strong> an analysis that was subsequently published (Q J Med 1997:90:723‐725). To quote Hedrick: “Not<br />

only did the article fail to summarize the psychiatric literature accurately, it omitted discussion of the many avenues<br />

now be<strong>in</strong>g explored on the organic underp<strong>in</strong>n<strong>in</strong>gs of (<strong>ME</strong>)CFS”. Follow<strong>in</strong>g Hedrick’s exposure to the Editor,<br />

Wessely blamed his peer‐reviewers for allow<strong>in</strong>g his mistakes to go unnoticed (personal communication).<br />

This is not an isolated example of Wessely blam<strong>in</strong>g his peer‐reviewers. There have been others, for example,<br />

when UK medical statistician Professor Mart<strong>in</strong> Bland, then at St George’s Hospital Medical School, London,<br />

po<strong>in</strong>ted out significant statistical errors <strong>in</strong> a paper by Wessely and Trudie Chalder, say<strong>in</strong>g that Wessely’s<br />

f<strong>in</strong>d<strong>in</strong>gs were “clearly impossible”, Wessely absolved himself from any blame, but Bland was robust:<br />

“Potentially <strong>in</strong>correct conclusions, based on faulty analysis, should not be allowed to rema<strong>in</strong> <strong>in</strong> the literature to be cited<br />

uncritically by others” (Fatigue and psychological distress. BMJ: 19 th February 2000:320:515‐516). Wessely was<br />

compelled to acknowledge on published record that his figures were <strong>in</strong>correct: “We have been attacked by<br />

greml<strong>in</strong>s. We f<strong>in</strong>d it hard to believe that the usually <strong>in</strong>fallible statistical reviewers at the BMJ could have overlooked<br />

this and wonder, totally ungallantly, if we can transfer the blame to the production side”.<br />

Published criticism of the Wessely School’s studies on “CFS/<strong>ME</strong>” is readily accessible for all to read,<br />

particularly for:<br />

• the use of a heterogeneous patient population (studies us<strong>in</strong>g mixed populations are not useful<br />

unless researchers disaggregate their f<strong>in</strong>d<strong>in</strong>gs)<br />

• selective manipulation of others’ work, claim<strong>in</strong>g it supports their own f<strong>in</strong>d<strong>in</strong>gs when such is not<br />

the case (for example, <strong>in</strong> the 1996 Jo<strong>in</strong>t Royal Colleges Report CR54, Wessely et al mention a paper<br />

by Bombardier and Buchwald [Arch Intern Med 1995:155:2105‐2110] and convey that it supports<br />

their own stance, whereas the paper actually states: “The fact that the same prognostic <strong>in</strong>dicators were<br />

not valid for the group with CFS challenges the assumption that previous outcome research on chronic<br />

fatigue is generalisable to patients with chronic fatigue syndrome”; Wessely et al also mention a paper by<br />

Sandman [Biol Psych 1993:33:618‐623] <strong>in</strong> apparent support of their own view that the results of<br />

neuropsychological test<strong>in</strong>g have been “<strong>in</strong>consistent”, but the paper itself concludes: “the performance<br />

of the CFIDS patients was sevenfold worse than either the control or depressed group. These results <strong>in</strong>dicate<br />

that the memory deficit <strong>in</strong> CFIDS was more severe than assumed by CDC criteria. A pattern emerged of<br />

bra<strong>in</strong> behaviour relationships support<strong>in</strong>g neurological compromise <strong>in</strong> CFS”<br />

• their focus on the s<strong>in</strong>gle symptom of “fatigue” whilst ignor<strong>in</strong>g other significant signs and<br />

symptoms associated with the cardiovascular, respiratory, neurological, endocr<strong>in</strong>e and<br />

immunological systems<br />

• generat<strong>in</strong>g conclusions before generat<strong>in</strong>g the data to support such conclusions, for example, <strong>in</strong> his<br />

paper on the status of vitam<strong>in</strong> B <strong>in</strong> CFS patients (JRSM 1999:92:183‐185), Wessely found a

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